Publications by authors named "Reinaldo Jones"

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Evobrutinib pathway to its major metabolite M463-2 and insights from a biotransformation and DDI perspective.
Holger Scheible, Hanno Schieferstein, Ralf Schmidt, Klaus Pusecker, Ulrike Gradhand, Reinaldo Jones

Xenobiotica· December 2023

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Discovery of quinazoline HPK1 inhibitors with high cellular potency.
Momar Toure, Theresa Johnson, Bin Li, Ralf Schmidt, Hong Ma, Reinaldo Jones, Christopher Jones

Bioorg Med Chem· September 2023

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Identification of Clinical Candidate M2698, a Dual p70S6K and Akt Inhibitor, for Treatment of PAM Pathway-Altered Cancers.
Lizbeth DeSelm, Bayard Huck, Ruoxi Lan, Constantin Neagu, Justin Potnick, Reinaldo Jones

J Med Chem· October 2021

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Discovery of potent and selective reversible Bruton's tyrosine kinase inhibitors.
Hui Qiu, Zahid Ali, Andrew Bender, Richard Caldwell, Yi-Ying Chen, Christopher Jones, Reinaldo Jones

Bioorg Med Chem· June 2021

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Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton's Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases.
Richard D Caldwell, Hui Qiu, Ben C Askew, Andrew T Bender, Nadia Brugger, Christopher Jones, Reinaldo C Jones

J Med Chem· September 2019

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Discovery of Affinity-Based Probes for Btk Occupancy Assays.
Hui Qiu, Richard Caldwell, Lesley Liu-Bujalski, Andreas Goutopoulos, Reinaldo Jones

ChemMedChem· January 2019

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Optimization of the efflux ratio and permeability of covalent irreversible BTK inhibitors.
Hui Qiu, Lesley Liu-Bujalski, Richard D Caldwell, Ariele Viacava Follis, Anna Gardberg, Christopher C V Jones, Reinaldo Jones

Bioorg Med Chem Lett· November 2018

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Discovery of a novel series of pyridine and pyrimidine carboxamides as potent and selective covalent inhibitors of Btk.
Richard Caldwell, Lesley Liu-Bujalski, Hui Qiu, Igor Mochalkin, Reinaldo Jones

Bioorg Med Chem Lett· November 2018

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Discovery of potent, highly selective covalent irreversible BTK inhibitors from a fragment hit.
Hui Qiu, Lesley Liu-Bujalski, Richard D Caldwell, Ariele Viacava Follis, Anna Gardberg, Reinaldo Jones

Bioorg Med Chem Lett· September 2018

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Synthesis and Cardiac Imaging of (18)F-Ligands Selective for β1-Adrenoreceptors.
Heike S Radeke, Ajay Purohit, Thomas D Harris, Kelley Hanson, Reinaldo Jones

ACS Med Chem Lett· September 2011

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Amino Acid derived enamides: synthesis and aminopeptidase activity.
Richard R Cesati, Greg Dwyer, Reinaldo C Jones, Megan P Hayes, Padmaja Yalamanchili

Org Lett· December 2007

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