Publications by authors named "Renee Litman"

Claim this Profile
S
Structure-based drug design of RN486, a potent and selective Bruton's tyrosine kinase (BTK) inhibitor, for the treatment of rheumatoid arthritis.
Yan Lou, Xiaochun Han, Andreas Kuglstatter, Rama K Kondru, Zachary K Sweeney, Renee Litman

J Med Chem· January 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Finding the perfect spot for fluorine: improving potency up to 40-fold during a rational fluorine scan of a Bruton's Tyrosine Kinase (BTK) inhibitor scaffold.
Yan Lou, Zachary K Sweeney, Andreas Kuglstatter, Dana Davis, David M Goldstein, Renee Litman

Bioorg Med Chem Lett· January 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of 6-(2,4-difluorophenoxy)-2-[3-hydroxy-1-(2-hydroxyethyl)propylamino]-8-methyl-8H-pyrido[2,3-d]pyrimidin-7-one (pamapimod) and 6-(2,4-difluorophenoxy)-8-methyl-2-(tetrahydro-2H-pyran-4-ylamino)pyrido[2,3-d]pyrimidin-7(8H)-one (R1487) as orally bioavailable and highly selective inhibitors of p38α mitogen-activated protein kinase.
David M Goldstein, Michael Soth, Tobias Gabriel, Nolan Dewdney, Andreas Kuglstatter, Renee Litman

J Med Chem· April 2011

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The relationship between physicochemical properties, in vitro activity and pharmacokinetic profiles of analogues of diamine-containing efflux pump inhibitors.
William J Watkins, Yakira Landaverry, Roger Léger, Renée Litman, Thomas E Renau

Bioorg Med Chem Lett· December 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis