Publications by authors named "Rex Pegram"

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Corrigendum to 'Comparison of In Vivo Derived and Scaled In Vitro Metabolic Rate Constants for Several Volatile Organic Compounds (VOCs)' [toxicology in vitro 68 (2020) start page-end page].
Elaina M Kenyon, Christopher Eklund, Rex A Pegram, John C Lipscomb

Toxicol In Vitro· September 2021

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Comparison of in vivo derived and scaled in vitro metabolic rate constants for several volatile organic compounds (VOCs).
Elaina M Kenyon, Christopher Eklund, Rex A Pegram, John C Lipscomb

Toxicol In Vitro· December 2020

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The Impact of Scaling Factor Variability on Risk-Relevant Pharmacokinetic Outcomes in Children: A Case Study Using Bromodichloromethane (BDCM).
Elaina M Kenyon, John C Lipscomb, Rex A Pegram, Barbara J George, Ronald N Hines

Toxicol Sci· February 2019

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The impact of variation in scaling factors on the estimation of internal dose metrics: a case study using bromodichloromethane (BDCM).
Elaina M Kenyon, Christopher Eklund, John C Lipscomb, Rex A Pegram

Toxicol Mech Methods· October 2016

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Development and application of a human PBPK model for bromodichloromethane to investigate the impacts of multi-route exposure.
Elaina M Kenyon, Christopher Eklund, Teresa Leavens, Rex A Pegram

J Appl Toxicol· September 2016

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Development of a human physiologically based pharmacokinetic (PBPK) model for dermal permeability for lindane.
Megan E Sawyer, Marina V Evans, Charles A Wilson, Lauren J Beesley, Lider S Leon, Rex A Pegram

Toxicol Lett· March 2016

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Estimating Potential Increased Bladder Cancer Risk Due to Increased Bromide Concentrations in Sources of Disinfected Drinking Waters.
Stig Regli, Jimmy Chen, Michael Messner, Michael S Elovitz, Frank J Letkiewicz, Rex A Pegram

Environ Sci Technol· November 2015

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Improving in vitro to in vivo extrapolation by incorporating toxicokinetic measurements: a case study of lindane-induced neurotoxicity.
Edward L Croom, Timothy J Shafer, Marina V Evans, William R Mundy, Chris R Eklund, Rex A Pegram

Toxicol Appl Pharmacol· February 2015

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Comparison of trihalomethanes in tap water and blood: a case study in the United States.
Zorimar Rivera-Núñez, J Michael Wright, Benjamin C Blount, Lalith K Silva, Elizabeth Jones, Rex A Pegram

Environ Health Perspect· May 2012

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Development of an inhalation physiologically based pharmacokinetic (PBPK) model for 2,2, 4-trimethylpentane (TMP) in male Long-Evans rats using gas uptake experiments.
Hisham A El-Masri, Sean Dowd, Rex A Pegram, Randy Harrison, Sisouphanh J Yavanhxay

Inhal Toxicol· December 2009

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Integrated disinfection by-products research: salmonella mutagenicity of water concentrates disinfected by chlorination and ozonation/postchlorination.
Larry D Claxton, Rex Pegram, Kathleen M Schenck, Jane Ellen Simmons, Sarah H Warren

J Toxicol Environ Health A· July 2008

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Cyanotoxins Workgroup report.
Rex A Pegram, Tonya Nichols, Stacey Etheridge, Andrew Humpage, Susan LeBlanc

Adv Exp Med Biol· June 2008

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Disposition of bromodichloromethane in humans following oral and dermal exposure.
Teresa L Leavens, Benjamin C Blount, David M DeMarini, Michael C Madden, John L Valentine, Rex A Pegram

Toxicol Sci· October 2007

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Bromodichloromethane inhibits human placental trophoblast differentiation.
Jiangang Chen, Twanda L Thirkill, Peter N Lohstroh, Susan R Bielmeier, Michael G Narotsky, Rex A Pegram

Toxicol Sci· March 2004

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In vitro biotransformation and genotoxicity of the drinking water disinfection byproduct bromodichloromethane: DNA binding mediated by glutathione transferase theta 1-1.
Matthew K Ross, Rex A Pegram

Toxicol Appl Pharmacol· March 2004

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Analysis of in vivo and in vitro DNA strand breaks from trihalomethane exposure.
David R Geter, Lina W Chang, Nancy M Hanley, Matthew K Ross, Rex A Pegram

J Carcinog· February 2004

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Effect of bromodichloromethane on chorionic gonadotrophin secretion by human placental trophoblast cultures.
Jiangang Chen, Gordon C Douglas, Twanda L Thirkill, Peter N Lohstroh, Susan R Bielmeier, Rex A Pegram

Toxicol Sci· November 2003

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Induction of DNA strand breaks by trihalomethanes in primary human lung epithelial cells.
Stefano Landi, Alessio Naccarati, Matthew K Ross, Nancy M Hanley, Lisa Dailey, Rex A Pegram

Mutat Res· July 2003

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[35S]-labeling of the Salmonella typhimurium glutathione pool to assess glutathione-mediated DNA binding by 1,2-dibromoethane.
Matthew K Ross, Rex A Pegram

Chem Biol Interact· July 2003

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Glutathione transferase theta 1-1-dependent metabolism of the water disinfection byproduct bromodichloromethane.
Matthew K Ross, Rex A Pegram

Chem Res Toxicol· February 2003

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Evidence for the involvement of CYP1A2 in the metabolism of bromodichloromethane in rat liver.
John W Allis, Brian P Anderson, Guangyu Zhao, Tracey M Ross, Rex A Pegram

Toxicology· July 2002

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Assessing exposure in epidemiologic studies to disinfection by-products in drinking water: report from an international workshop.
Tye E Arbuckle, Steve E Hrudey, Stuart W Krasner, Jay R Nuckols, Susan D Richardson, Rex A Pegram

Environ Health Perspect· February 2002

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