Publications by authors named "Ria Sircar"

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Patched 1 regulates Smoothened by controlling sterol binding to its extracellular cysteine-rich domain.
Maia Kinnebrew, Rachel E Woolley, T Bertie Ansell, Eamon F X Byrne, Sara Frigui, Ria Sircar

Sci Adv· June 2022

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Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes.
Maia Kinnebrew, Giovanni Luchetti, Ria Sircar, Sara Frigui, Lucrezia Vittoria Viti

Elife· October 2021

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Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates.
Jonas Abdel-Khalik, Thomas Hearn, Alison L Dickson, Peter J Crick, Eylan Yutuc, Ria Sircar

J Steroid Biochem Mol Biol· February 2021

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G protein-coupled receptors control the sensitivity of cells to the morphogen Sonic Hedgehog.
Ganesh V Pusapati, Jennifer H Kong, Bhaven B Patel, Mina Gouti, Andreas Sagner, Ria Sircar

Sci Signal· February 2018

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Production, characterization, and assessment of a stable analog of the response regulator CheY-phosphate from Thermotoga maritima.
Matthew S Beyersdorf, Ria Sircar, Daniel B Lookadoo, Cory J Bottone, Michael J Lynch

Protein Sci· August 2017

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Co-Folding of a FliF-FliG Split Domain Forms the Basis of the MS:C Ring Interface within the Bacterial Flagellar Motor.
Michael J Lynch, Robert Levenson, Eun A Kim, Ria Sircar, David F Blair

Structure· February 2017

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Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling.
Giovanni Luchetti, Ria Sircar, Jennifer H Kong, Sigrid Nachtergaele, Andreas Sagner

Elife· October 2016

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Structural basis of Smoothened regulation by its extracellular domains.
Eamon F X Byrne, Ria Sircar, Paul S Miller, George Hedger, Giovanni Luchetti

Nature· July 2016

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Assembly states of FliM and FliG within the flagellar switch complex.
Ria Sircar, Peter P Borbat, Michael J Lynch, Jaya Bhatnagar, Matthew S Beyersdorf

J Mol Biol· February 2015

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Structure and activity of the flagellar rotor protein FliY: a member of the CheC phosphatase family.
Ria Sircar, Anna R Greenswag, Alexandrine M Bilwes, Gabriela Gonzalez-Bonet, Brian R Crane

J Biol Chem· May 2013

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Architecture of the soluble receptor Aer2 indicates an in-line mechanism for PAS and HAMP domain signaling.
Michael V Airola, Doowon Huh, Nattakan Sukomon, Joanne Widom, Ria Sircar

J Mol Biol· March 2013

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Self-association of the histidine kinase CheA as studied by pulsed dipolar ESR spectroscopy.
Jaya Bhatnagar, Ria Sircar, Peter P Borbat, Jack H Freed, Brian R Crane

Biophys J· May 2012

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