Publications by authors named "Richard Alm"

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Highly potent quinoxalinediones inhibit α-hemolysin and ameliorate Staphylococcus aureus lung infections.
Aditya Shekhar, Raffaella Di Lucrezia, Karoline Jerye, Vadim S Korotkov, Kirsten Harmrolfs, Richard Alm

Cell Host Microbe· April 2025

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Addressing urgent priorities in antibiotic development: insights from WHO 2023 antibacterial clinical pipeline analyses.
Daniela Melchiorri, Tamarie Rocke, Richard A Alm, Alexandra M Cameron, Valeria Gigante

Lancet Microbe· March 2025

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Multi-year analysis of the global preclinical antibacterial pipeline: trends and gaps.
Valeria Gigante, Richard A Alm, Daniela Melchiorri, Tamarie Rocke, Cesar A Arias

Antimicrob Agents Chemother· August 2024

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Antigenic landscapes on pore-forming toxins reveal insights into specificity and cross-neutralization.
Shweta Kailasan, Ravi Kant, Madeleine Noonan-Shueh, Tulasikumari Kanipakala, Grant Liao, Richard A Alm

MAbs· June 2022

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Reply to Kaye and Belley, "Third-Generation Cephalosporin-Resistant Are Critical Priority Pathogens, Too!".
Mark S Butler, Valeria Gigante, Hatim Sati, Sarah Paulin, Laila Al-Sulaiman, Richard A Alm

Antimicrob Agents Chemother· April 2022

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Analysis of the Clinical Pipeline of Treatments for Drug-Resistant Bacterial Infections: Despite Progress, More Action Is Needed.
Mark S Butler, Valeria Gigante, Hatim Sati, Sarah Paulin, Laila Al-Sulaiman, Richard A Alm

Antimicrob Agents Chemother· March 2022

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The CARB-X Portfolio of Nontraditional Antibacterial Products.
Erin M Duffy, Ed T Buurman, Su L Chiang, Nadia R Cohen, Maria Uria-Nickelsen, Richard A Alm

ACS Infect Dis· August 2021

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A one health framework to estimate the cost of antimicrobial resistance.
Chantal M Morel, Richard A Alm, Christine Årdal, Alessandra Bandera, Giacomo M Bruno

Antimicrob Resist Infect Control· November 2020

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A novel pre-clinical antibacterial pipeline database.
Sarah Paulin, Richard A Alm, Peter Beyer

PLoS One· September 2020

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Narrow-Spectrum Antibacterial Agents-Benefits and Challenges.
Richard A Alm, Sushmita D Lahiri

Antibiotics (Basel)· July 2020

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Innovation in Antimicrobial Resistance: The CARB-X Perspective.
Richard A Alm, Karen Gallant

ACS Infect Dis· June 2020

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Ceftaroline efficacy against high-MIC clinical Staphylococcus aureus isolates in an in vitro hollow-fibre infection model.
Renu Singh, Mashal Almutairi, Richard A Alm, Sushmita D Lahiri, Maryann San Martin

J Antimicrob Chemother· October 2017

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Identification of non-PBP2a resistance mechanisms in Staphylococcus aureus after serial passage with ceftaroline: involvement of other PBPs.
Sushmita D Lahiri, Richard A Alm

J Antimicrob Chemother· November 2016

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Structural and sequence analysis of class A β-lactamases with respect to avibactam inhibition: impact of Ω-loop variations.
Sushmita D Lahiri, Patricia A Bradford, Wright W Nichols, Richard A Alm

J Antimicrob Chemother· October 2016

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Multi-center and multi-method evaluation of in vitro activities of ceftaroline against S. aureus.
Laura M Koeth, Petra Apfalter, Karsten Becker, Giovanni Gesu, Luis Martínez-Martínez, Richard A Alm

Diagn Microbiol Infect Dis· August 2016

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Identification of Novel VEB β-Lactamase Enzymes and Their Impact on Avibactam Inhibition.
Sushmita D Lahiri, Richard A Alm

Antimicrob Agents Chemother· May 2016

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Multidrug-Resistant Neisseria gonorrhoeae Isolates from Nanjing, China, Are Sensitive to Killing by a Novel DNA Gyrase Inhibitor, ETX0914 (AZD0914).
Xiao-Hong Su, Bao-Xi Wang, Wen-Jing Le, Yu-Rong Liu, Chuan Wan, Richard A Alm

Antimicrob Agents Chemother· January 2016

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Potential of Staphylococcus aureus isolates carrying different PBP2a alleles to develop resistance to ceftaroline.
Sushmita D Lahiri, Richard A Alm

J Antimicrob Chemother· January 2016

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In Vitro Activity of Ceftaroline against Staphylococcus aureus Isolated in 2012 from Asia-Pacific Countries as Part of the AWARE Surveillance Program.
Douglas J Biedenbach, Richard A Alm, Sushmita D Lahiri, Edina Reiszner, Daryl J Hoban

Antimicrob Agents Chemother· January 2016

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In Vitro Activity of Ceftaroline against Staphylococcus aureus Isolates Collected in 2012 from Latin American Countries as Part of the AWARE Surveillance Program.
Douglas J Biedenbach, Daryl J Hoban, Edina Reiszner, Sushmita D Lahiri, Richard A Alm

Antimicrob Agents Chemother· December 2015

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Molecular characterization of MRSA isolates bracketing the current EUCAST ceftaroline-susceptible breakpoint for Staphylococcus aureus: the role of PBP2a in the activity of ceftaroline.
Sushmita D Lahiri, Robert E McLaughlin, James D Whiteaker, Jane E Ambler, Richard A Alm

J Antimicrob Chemother· September 2015

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Insights into the mechanism of inhibition of novel bacterial topoisomerase inhibitors from characterization of resistant mutants of Staphylococcus aureus.
Sushmita D Lahiri, Amy Kutschke, Kathy McCormack, Richard A Alm

Antimicrob Agents Chemother· September 2015

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Ceftaroline Activity against mecC-Containing Staphylococcus aureus.
Sushmita D Lahiri, Richard A Alm

J Clin Microbiol· September 2015

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Corrigendum: Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases.
Gregory S Basarab, Gunther H Kern, John McNulty, John P Mueller, Kenneth Lawrence, Richard A Alm

Sci Rep· September 2015

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Responding to the challenge of untreatable gonorrhea: ETX0914, a first-in-class agent with a distinct mechanism-of-action against bacterial Type II topoisomerases.
Gregory S Basarab, Gunther H Kern, John McNulty, John P Mueller, Kenneth Lawrence, Richard A Alm

Sci Rep· July 2015

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