Publications by authors named "Richard Appleton"

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Review of the new APLS guideline (2022): Management of the convulsing child.
Melody Bacon, Richard Appleton, Harish Bangalore, Celia Brand, Juliet Browning

Arch Dis Child Educ Pract Ed· February 2023

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Optimal Management of Status Epilepticus in Children in the Emergency Setting: A Review of Recent Advances.
Shrouk Messahel, Louise Bracken, Richard Appleton

Open Access Emerg Med· September 2022

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Lamotrigine versus levetiracetam or zonisamide for focal epilepsy and valproate versus levetiracetam for generalised and unclassified epilepsy: two SANAD II non-inferiority RCTs.
Anthony G Marson, Girvan Burnside, Richard Appleton, Dave Smith, John Paul Leach

Health Technol Assess· December 2021

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The SANAD II study of the effectiveness and cost-effectiveness of levetiracetam, zonisamide, or lamotrigine for newly diagnosed focal epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial.
Anthony Marson, Girvan Burnside, Richard Appleton, Dave Smith, John Paul Leach

Lancet· April 2021

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The SANAD II study of the effectiveness and cost-effectiveness of valproate versus levetiracetam for newly diagnosed generalised and unclassifiable epilepsy: an open-label, non-inferiority, multicentre, phase 4, randomised controlled trial.
Anthony Marson, Girvan Burnside, Richard Appleton, Dave Smith, John Paul Leach

Lancet· April 2021

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Seven-step framework to enhance practitioner explanations and parental understandings of research without prior consent in paediatric emergency and critical care trials.
Louise Roper, Mark D Lyttle, Carrol Gamble, Amy Humphreys, Shrouk Messahel, Richard Appleton

Emerg Med J· March 2021

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Planning for success: overcoming challenges to recruitment and conduct of an open-label emergency department-led paediatric trial.
Louise Roper, Mark D Lyttle, Carrol Gamble, Amy Humphreys, Shrouk Messahel, Richard Appleton

Emerg Med J· March 2021

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Levetiracetam as an alternative to phenytoin for second-line emergency treatment of children with convulsive status epilepticus: the EcLiPSE RCT.
Richard E Appleton, Naomi Ea Rainford, Carrol Gamble, Shrouk Messahel, Amy Humphreys

Health Technol Assess· November 2020

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Study protocol for a pragmatic randomised controlled trial comparing the effectiveness and cost-effectiveness of levetiracetam and zonisamide versus standard treatments for epilepsy: a comparison of standard and new antiepileptic drugs (SANAD-II).
Silviya Balabanova, Claire Taylor, Graeme Sills, Girvan Burnside, Catrin Plumpton, Richard Appleton

BMJ Open· August 2020

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Second-line anticonvulsants for paediatric convulsive status epilepticus.
Richard E Appleton

Lancet· April 2020

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Tuberous Sclerosis Complex (TSC): Expert Recommendations for Provision of Coordinated Care.
Nicholas M P Annear, Richard E Appleton, Zahabiyah Bassi, Rupesh Bhatt, Patrick F Bolton

Front Neurol· November 2019

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Cerebral palsy: not always what it seems.
Richard E Appleton, Rajat Gupta

Arch Dis Child· August 2019

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Levetiracetam versus phenytoin for second-line treatment of paediatric convulsive status epilepticus (EcLiPSE): a multicentre, open-label, randomised trial.
Mark D Lyttle, Naomi E A Rainford, Carrol Gamble, Shrouk Messahel, Amy Humphreys, Richard E Appleton

Lancet· May 2019

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How can transition to adult care be best orchestrated for adolescents with epilepsy?
Peter R Camfield, Danielle Andrade, Carole S Camfield, Jaime Carrizosa-Moog, Richard Appleton

Epilepsy Behav· April 2019

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Enhancing practitioners' confidence in recruitment and consent in the EcLiPSE trial: a mixed-method evaluation of site training - a Paediatric Emergency Research in the United Kingdom and Ireland (PERUKI) study.
Kerry Woolfall, Louise Roper, Amy Humphreys, Mark D Lyttle, Shrouk Messahel, Richard Appleton

Trials· March 2019

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Children's views on research without prior consent in emergency situations: a UK qualitative study.
Louise Roper, Frances C Sherratt, Bridget Young, Paul McNamara, Angus Dawson, Richard Appleton

BMJ Open· June 2018

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Randomized, dose-ranging safety trial of cannabidiol in Dravet syndrome.
Orrin Devinsky, Anup D Patel, Elizabeth A Thiele, Matthew H Wong, Richard Appleton

Neurology· April 2018

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Panayiotopoulos syndrome and benign partial epilepsy with centro-temporal spikes: A comparative incidence study.
Elaine Weir, John Gibbs, Richard Appleton

Seizure· April 2018

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Seizures and Encephalitis in Myelin Oligodendrocyte Glycoprotein IgG Disease vs Aquaporin 4 IgG Disease.
Shahd H M Hamid, Dan Whittam, Mariyam Saviour, Amal Alorainy, Kerry Mutch, Richard Appleton

JAMA Neurol· January 2018

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Clinical and molecular characterization of -related severe early-onset epilepsy.
Amy McTague, Umesh Nair, Sony Malhotra, Esther Meyer, Natalie Trump, Richard Appleton

Neurology· January 2018

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Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children.
Amy McTague, Timothy Martland, Richard Appleton

Cochrane Database Syst Rev· January 2018

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Seizures, safety and submersion: sense and sensibility.
Richard E Appleton

Arch Dis Child· October 2017

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Consensus-based guidelines for Video EEG monitoring in the pre-surgical evaluation of children with epilepsy in the UK.
Ronit M Pressler, Stefano Seri, Nick Kane, Tim Martland, Sushma Goyal, Richard Appleton

Seizure· August 2017

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Resource implications of preparing individual participant data from a clinical trial to share with external researchers.
Catrin Tudur Smith, Sarah Nevitt, Duncan Appelbe, Richard Appleton, Pete Dixon

Trials· July 2017

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Emergency treatment with levetiracetam or phenytoin in status epilepticus in children-the EcLiPSE study: study protocol for a randomised controlled trial.
Mark D Lyttle, Carrol Gamble, Shrouk Messahel, Helen Hickey, Anand Iyer, Richard E Appleton

Trials· June 2017

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