Publications by authors named "Richard B Markham"

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MIP3α-Rel intranasal DNA vaccination induces reactive T-cell infiltration into the lungs of mice and macaques.
James T Gordy, Jean J Zheng, Amanda R Maxwell, Rowan E Bates, Alannah D Taylor, Richard B Markham

Vaccine· August 2025

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J3ExoA: A Novel Anti-HIV Immunotoxin Fusion of Anti-Gp120 J3VHH and PE38 Fragment of Exotoxin A.
Seth H Pincus, Kun Luo, Tami Peters, James T Gordy, Frances M Cole, Richard B Markham

Pharmaceuticals (Basel)· August 2025

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MIP-3α-antigen fusion DNA vaccine enhances sex differences in tuberculosis model and alters dendritic cell activity early post vaccination.
James T Gordy, Rowan E Bates, Elizabeth Glass, Jacob Meza, Yangchen Li, Richard B Markham

Sci Rep· July 2025

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Novel Vaccines Targeting the Highly Conserved SARS-CoV-2 ORF3a Ectodomain Elicit Immunogenicity in Mouse Models.
Jacob Meza, Elizabeth Glass, Avinaash K Sandhu, Yangchen Li, Styliani Karanika, Richard B Markham

Vaccines (Basel)· February 2025

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Brief Communication: Combination of an MIP3α-Antigen Fusion Therapeutic DNA Vaccine With Treatments of IFNα and 5-Aza-2'Deoxycytidine Enhances Activated Effector CD8+ T Cells Expressing CD11c in the B16F10 Melanoma Model.
Kaitlyn Fessler, Jiaqi Zhang, Avinaash K Sandhu, Yinan Hui, Aakanksha R Kapoor, Richard B Markham

J Immunother· January 2025

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MIP-3α-antigen fusion DNA vaccine enhances sex differences in tuberculosis model and alters dendritic cell activity early post vaccination.
James T Gordy, Rowan E Bates, Elizabeth Glass, Jacob Meza, Yangchen Li, Richard B Markham

Res Sq· January 2025

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MIP3α-Rel intranasal DNA vaccination induces reactive T-cell infiltration into the lungs in mice and macaques.
James T Gordy, Jean J Zheng, Amanda R Maxwell, Alannah D Taylor, Styliani Karanika, Richard B Markham

bioRxiv· September 2024

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Therapeutic DNA Vaccine Targeting Persisters Shortens Curative Tuberculosis Treatment.
Styliani Karanika, Tianyin Wang, Addis Yilma, Jennie Ruelas Castillo, James T Gordy, Richard B Markham

bioRxiv· September 2024

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Combination of a MIP3α-antigen fusion therapeutic DNA vaccine with treatments of IFNα and 5-Aza-2'Deoxycytidine enhances activated effector CD8+ T cells expressing CD11c in the B16F10 melanoma model.
Kaitlyn Fessler, Jiaqi Zhang, Avinaash K Sandhu, Yinan Hui, Aakanksha R Kapoor, Richard B Markham

Res Sq· August 2024

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A SARS-CoV-2 RBD vaccine fused to the chemokine MIP-3α elicits sustained murine antibody responses over 12 months and enhanced lung T-cell responses.
James Tristan Gordy, Yinan Hui, Courtney Schill, Tianyin Wang, Fengyixin Chen, Richard B Markham

Front Immunol· February 2024

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IFNα and 5-Aza-2'-deoxycytidine combined with a dendritic-cell targeting DNA vaccine alter tumor immune cell infiltration in the B16F10 melanoma model.
James T Gordy, Avinaash K Sandhu, Kaitlyn Fessler, Kun Luo, Aakanksha R Kapoor, Richard B Markham

Front Immunol· February 2023

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An intranasal stringent response vaccine targeting dendritic cells as a novel adjunctive therapy against tuberculosis.
Styliani Karanika, James T Gordy, Pranita Neupane, Theodoros Karantanos, Jennie Ruelas Castillo, Richard B Markham

Front Immunol· October 2022

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Antibiotic Treatment Shapes the Antigenic Environment During Chronic TB Infection, Offering Novel Targets for Therapeutic Vaccination.
Yu-Min Chuang, Noton K Dutta, James T Gordy, Victoria L Campodónico, Michael L Pinn, Richard B Markham

Front Immunol· March 2021

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A chemokine-fusion vaccine targeting immature dendritic cells elicits elevated antibody responses to malaria sporozoites in infant macaques.
Kun Luo, James T Gordy, Fidel Zavala, Richard B Markham

Sci Rep· January 2021

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Treatment with an immature dendritic cell-targeting vaccine supplemented with IFN-α and an inhibitor of DNA methylation markedly enhances survival in a murine melanoma model.
James T Gordy, Kun Luo, Aakanksha Kapoor, Emily S Kim, Samuel K Ayeh, Richard B Markham

Cancer Immunol Immunother· April 2020

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Anti-IL-10-mediated Enhancement of Antitumor Efficacy of a Dendritic Cell-targeting MIP3α-gp100 Vaccine in the B16F10 Mouse Melanoma Model Is Dependent on Type I Interferons.
James T Gordy, Kun Luo, Brian Francica, Charles Drake, Richard B Markham

J Immunother· May 2018

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Inhibition of Vpx-Mediated SAMHD1 and Vpr-Mediated Host Helicase Transcription Factor Degradation by Selective Disruption of Viral CRL4 (DCAF1) E3 Ubiquitin Ligase Assembly.
Hong Wang, Haoran Guo, Jiaming Su, Yajuan Rui, Wenwen Zheng, Richard B Markham

J Virol· May 2017

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Extended protection capabilities of an immature dendritic-cell targeting malaria sporozoite vaccine.
Kun Luo, Fidel Zavala, James Gordy, Hong Zhang, Richard B Markham

Vaccine· April 2017

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Fusion of the dendritic cell-targeting chemokine MIP3α to melanoma antigen Gp100 in a therapeutic DNA vaccine significantly enhances immunogenicity and survival in a mouse melanoma model.
James T Gordy, Kun Luo, Hong Zhang, Arya Biragyn, Richard B Markham

J Immunother Cancer· December 2016

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Monoclonal and Single Domain Antibodies Targeting β-Integrin Subunits Block Sexual Transmission of HIV-1 in In Vitro and In Vivo Model Systems.
Janet Tai Guedon, Kun Luo, Hong Zhang, Richard B Markham

J Acquir Immune Defic Syndr· July 2015

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Fusion of antigen to a dendritic cell targeting chemokine combined with adjuvant yields a malaria DNA vaccine with enhanced protective capabilities.
Kun Luo, Hong Zhang, Fidel Zavala, Arya Biragyn, Diego A Espinosa, Richard B Markham

PLoS One· January 2015

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Antiviral activity of a single-domain antibody immunotoxin binding to glycoprotein D of herpes simplex virus 2.
Eileen M Geoghegan, Hong Zhang, Prashant J Desai, Arya Biragyn, Richard B Markham

Antimicrob Agents Chemother· January 2015

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A first-in-class NAE inhibitor, MLN4924, blocks lentiviral infection in myeloid cells by disrupting neddylation-dependent Vpx-mediated SAMHD1 degradation.
Wei Wei, Haoran Guo, Xianjun Liu, Hong Zhang, Lei Qian, Richard B Markham

J Virol· January 2014

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Multiple-infection and recombination in HIV-1 within a longitudinal cohort of women.
Alan R Templeton, Melissa G Kramer, Joseph Jarvis, Jeanne Kowalski, Stephen Gange, Richard B Markham

Retrovirology· June 2009

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Relationship of injection drug use, antiretroviral therapy resistance, and genetic diversity in the HIV-1 pol gene.
Jeanne Kowalski, Stephen J Gange, Michael F Schneider, Hua-Ling Tsai, Alan Templeton, Richard B Markham

J Acquir Immune Defic Syndr· April 2009

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