Publications by authors named "Richard D Braatz"

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Fictitious phase separation in Li layered oxides driven by electro-autocatalysis.
Jungjin Park, Hongbo Zhao, Stephen Dongmin Kang, Kipil Lim, Chia-Chin Chen, Young-Sang Yu, Richard D Braatz, David A Shapiro, Jihyun Hong, Michael F Toney

Nat Mater· July 2021

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Closed-loop optimization of fast-charging protocols for batteries with machine learning.
Peter M Attia, Aditya Grover, Norman Jin, Kristen A Severson, Todor M Markov, Yang-Hung Liao, Michael H Chen, Bryan Cheong, Nicholas Perkins, Zi Yang

Nature· February 2020

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Mechanistic Modeling of Continuous Lyophilization for Biopharmaceutical Manufacturing.
Prakitr Srisuma, Gang Chen, Richard D Braatz

Adv Sci (Weinh)· December 2025

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End-to-end digital twin software for continuous mRNA manufacturing.
Mohammed Aatif Shahab, Nathan Merica Stover, Hasan Al-Mahayni, Prakitr Srisuma, Jie Wang, Richard D Braatz

Int J Pharm· December 2025

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Mechanistic modeling of lipid nanoparticle formation for the delivery of nucleic acid therapeutics.
Pavan K Inguva, Saikat Mukherjee, Pierre J Walker, Vico Tenberg, Cedric Devos, Richard D Braatz

Biotechnol Adv· November 2025

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Model-Based Optimization of Fed-Batch In Vitro Transcription.
Nathan Merica Stover, Soroush Ahmadi, Jacob Rosenfeld, Francesco Destro, Allan S Myerson, Richard D Braatz

Chembiochem· November 2025

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Selective Enrichment of Full Capsids of Adeno-Associated Virus.
Vivekananda Bal, Jacqueline M Wolfrum, Paul W Barone, Stacy L Springs, Anthony J Sinskey, Richard D Braatz

ACS Nano· October 2025

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Hyperspectral Imaging Techniques for Lyophilization: Advances in Data-Driven Modeling Strategies and Applications.
Huiwen Yu, Prakitr Srisuma, Cedric Devos, Jie Wang, Allan S Myerson, Richard D Braatz

Adv Sci (Weinh)· September 2025

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Manufacturing mRNA-Loaded Lipid Nanoparticles with Precise Size and Morphology Control.
Cedric Devos, Aniket Udepurkar, Peter Sagmeister, Ariana S Hodlewsky, Julie Chen, Richard D Braatz

ACS Nano· September 2025

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Perfusion-Based Production of rAAV via an Intensified Transient Transfection Process.
Tam N T Nguyen, Damdae Park, Christopher T Canova, Jose Sangerman, Prasanna Srinivasan, Richard D Braatz

Biotechnol Bioeng· June 2025

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Structure and Morphology of Lipid Nanoparticles for Nucleic Acid Drug Delivery: A Review.
Aniket Udepurkar, Cedric Devos, Peter Sagmeister, Francesco Destro, Pavan Inguva, Richard D Braatz

ACS Nano· June 2025

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An Integrated Experimental and Modeling Approach for Crystallization of Complex Biotherapeutics.
Vivekananda Bal, Moo Sun Hong, Jacqueline M Wolfrum, Paul W Barone, Stacy L Springs, Richard D Braatz

Cryst Growth Des· June 2025

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HEK-omics: The promise of omics to optimize HEK293 for recombinant adeno-associated virus (rAAV) gene therapy manufacturing.
Sai Guna Ranjan Gurazada, Hannah M Kennedy, Richard D Braatz, Steven J Mehrman, Shawn W Polson

Biotechnol Adv· April 2025

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Developing ultra-high concentration formulations of human immune globulins for subcutaneous injectables.
Jayprakash Yadav, Shihab Uddin, Francesco Civati, Wenchuan Ma, Andreas Liebminger, Richard D Braatz

J Pharm Sci· March 2025

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Enhanced O-glycosylation site prediction using explainable machine learning technique with spatial local environment.
Seokyoung Hong, Krishna Gopal Chattaraj, Jing Guo, Bernhardt L Trout, Richard D Braatz

Bioinformatics· February 2025

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Multidose transient transfection of human embryonic kidney 293 cells modulates recombinant adeno-associated virus2/5 Rep protein expression and influences the enrichment fraction of filled capsids.
Prasanna Srinivasan, Christopher T Canova, Sha Sha, Tam N T Nguyen, John Joseph, Richard D Braatz

Biotechnol Bioeng· December 2024

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The state of technological advancement to address challenges in the manufacture of rAAV gene therapies.
Francesco Destro, Weida Wu, Prasanna Srinivasan, John Joseph, Vivekananda Bal, Richard D Braatz

Biotechnol Adv· November 2024

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Real-time estimation of bound water concentration during lyophilization with temperature-based state observers.
Prakitr Srisuma, George Barbastathis, Richard D Braatz

Int J Pharm· November 2024

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Efficient Simulation of Viral Transduction and Propagation for Biomanufacturing.
Francesco Destro, Richard D Braatz

ACS Synth Biol· October 2024

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Mechanistic modeling of in vitro transcription incorporating effects of magnesium pyrophosphate crystallization.
Nathan Merica Stover, Krystian Ganko, Richard D Braatz

Biotechnol Bioeng· September 2024

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Non-invasive estimation of the powder size distribution from a single speckle image.
Qihang Zhang, Ajinkya Pandit, Zhiguang Liu, Zhen Guo, Shashank Muddu, Richard D Braatz

Light Sci Appl· August 2024

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Correction: Analysis of Poly(ethylene terephthalate) degradation kinetics of evolved IsPETase variants using a surface crowding mode.
En Ze Linda Zhong-Johnson, Ziyue Dong, Christopher T Canova, Francesco Destro, Marina Cañellas, Richard D Braatz

J Biol Chem· April 2024

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Analysis of Poly(ethylene terephthalate) degradation kinetics of evolved IsPETase variants using a surface crowding model.
En Ze Linda Zhong-Johnson, Ziyue Dong, Christopher T Canova, Francesco Destro, Marina Cañellas, Richard D Braatz

J Biol Chem· March 2024

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Learning heterogeneous reaction kinetics from X-ray videos pixel by pixel.
Hongbo Zhao, Haitao Dean Deng, Alexander E Cohen, Jongwoo Lim, Yiyang Li, Richard D Braatz

Nature· September 2023

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Mechanistic modeling explains the production dynamics of recombinant adeno-associated virus with the baculovirus expression vector system.
Francesco Destro, John Joseph, Prasanna Srinivasan, Joshua M Kanter, Caleb Neufeld, Richard D Braatz

Mol Ther Methods Clin Dev· September 2023

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Mechanistic modeling of viral particle production.
Christopher T Canova, Pavan K Inguva, Richard D Braatz

Biotechnol Bioeng· March 2023

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Extracting particle size distribution from laser speckle with a physics-enhanced autocorrelation-based estimator (PEACE).
Qihang Zhang, Janaka C Gamekkanda, Ajinkya Pandit, Wenlong Tang, Charles Papageorgiou, Richard D Braatz

Nat Commun· March 2023

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