Publications by authors named "Richard D Hutton"

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Mapping the Topography of a Protein Energy Landscape.
Richard D Hutton, James Wilkinson, Mauro Faccin, Elin M Sivertsson, Alessandro Pelizzola

J Am Chem Soc· November 2015

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Complex Formation between Two Biosynthetic Enzymes Modifies the Allosteric Regulatory Properties of Both: AN EXAMPLE OF MOLECULAR SYMBIOSIS.
Nicola J Blackmore, Ali Reza Nazmi, Richard D Hutton, Melissa N Webby, Edward N Baker

J Biol Chem· July 2015

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Single-molecule characterization of Fen1 and Fen1/PCNA complexes acting on flap substrates.
Timothy D Craggs, Richard D Hutton, Alfonso Brenlla, Malcolm F White, J Carlos Penedo

Nucleic Acids Res· February 2014

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Three sites and you are out: ternary synergistic allostery controls aromatic amino acid biosynthesis in Mycobacterium tuberculosis.
Nicola J Blackmore, Sebastian Reichau, Wanting Jiao, Richard D Hutton, Edward N Baker

J Mol Biol· May 2013

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Dynamic cross-talk among remote binding sites: the molecular basis for unusual synergistic allostery.
Wanting Jiao, Richard D Hutton, Penelope J Cross, Geoffrey B Jameson, Emily J Parker

J Mol Biol· January 2012

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An extended β7α7 substrate-binding loop is essential for efficient catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase.
Timothy M Allison, Richard D Hutton, Wanting Jiao, Benjamin J Gloyne, Evan B Nimmo

Biochemistry· November 2011

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Targeting the role of a key conserved motif for substrate selection and catalysis by 3-deoxy-D-manno-octulosonate 8-phosphate synthase.
Timothy M Allison, Richard D Hutton, Fiona C Cochrane, Jeffrey A Yeoman, Geoffrey B Jameson

Biochemistry· May 2011

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Potent inhibitors of a shikimate pathway enzyme from Mycobacterium tuberculosis: combining mechanism- and modeling-based design.
Sebastian Reichau, Wanting Jiao, Scott R Walker, Richard D Hutton, Edward N Baker

J Biol Chem· May 2011

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Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis.
Celia J Webby, Wanting Jiao, Richard D Hutton, Nicola J Blackmore, Heather M Baker

J Biol Chem· October 2010

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Specificity and mutational analysis of the metal-dependent 3-deoxy-D-manno-octulosonate 8-phosphate synthase from Acidithiobacillus ferrooxidans.
Timothy M Allison, Jeffrey A Yeoman, Richard D Hutton, Fiona C Cochrane, Geoffrey B Jameson

Biochim Biophys Acta· July 2010

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PCNA and XPF cooperate to distort DNA substrates.
Richard D Hutton, Timothy D Craggs, Malcolm F White, J Carlos Penedo

Nucleic Acids Res· March 2010

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PCNA stimulates catalysis by structure-specific nucleases using two distinct mechanisms: substrate targeting and catalytic step.
Richard D Hutton, Jennifer A Roberts, J Carlos Penedo, Malcolm F White

Nucleic Acids Res· December 2008

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A physical map of the mouse genome.
Simon G Gregory, Mandeep Sekhon, Jacqueline Schein, Shaying Zhao, Kazutoyo Osoegawa, Richard D Hutton

Nature· August 2002

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