Publications by authors named "Richard Eglen"

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Human iPS Cell-Derived Patient Tissues and 3D Cell Culture Part 1: Target Identification and Lead Optimization.
Richard M Eglen, Terry Reisine

SLAS Technol· February 2019

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Human iPS Cell-Derived Patient Tissues and 3D Cell Culture Part 2: Spheroids, Organoids, and Disease Modeling.
Richard M Eglen, Terry Reisine

SLAS Technol· February 2019

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Convergence of Three-Dimensional Cell Culture and Human iPS Cells: Improving Clinical Relevance in Drug Discovery.
Richard M Eglen

SLAS Technol· February 2019

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Three-Dimensional Cell Culture: A Rapidly Emerging Approach to Cellular Science and Drug Discovery.
Richard M Eglen, Jean-Louis Klein

SLAS Discov· June 2017

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Three-Dimensional Cell Cultures in Drug Discovery and Development.
Ye Fang, Richard M Eglen

SLAS Discov· June 2017

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Three-Dimensional Cell Culture Assays: Are They More Predictive of In Vivo Efficacy than 2D Monolayer Cell-Based Assays?
Sitta Sittampalam, Richard Eglen, Stephen Ferguson, Jason Thomas Maynes, Kenneth Olden

Assay Drug Dev Technol· June 2015

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Drug Discovery Goes Three-Dimensional: Goodbye to Flat High-Throughput Screening?
Richard M Eglen, David H Randle

Assay Drug Dev Technol· June 2015

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Overview of muscarinic receptor subtypes.
Richard M Eglen

Handb Exp Pharmacol· April 2012

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Screening for compounds that modulate epigenetic regulation of the transcriptome: an overview.
Richard M Eglen, Terry Reisine

J Biomol Screen· December 2011

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Drug discovery and the human kinome: recent trends.
Richard Eglen, Terry Reisine

Pharmacol Ther· May 2011

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Primary cells and stem cells in drug discovery: emerging tools for high-throughput screening.
Richard Eglen, Terry Reisine

Assay Drug Dev Technol· April 2011

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In vitro isolated tissue functional muscarinic receptor assays.
M Teresa Pulido-Rios, Tod Steinfeld, Scott Armstrong, Nikki Watson, Agnes Choppin, Richard Eglen

Curr Protoc Pharmacol· March 2010

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Human kinome drug discovery and the emerging importance of atypical allosteric inhibitors.
Richard M Eglen, Terry Reisine

Expert Opin Drug Discov· March 2010

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New insights into GPCR function: implications for HTS.
Richard M Eglen, Terry Reisine

Methods Mol Biol· July 2009

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The current status of drug discovery against the human kinome.
Richard M Eglen, Terry Reisine

Assay Drug Dev Technol· February 2009

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Photoproteins: important new tools in drug discovery.
Richard M Eglen, Terry Reisine

Assay Drug Dev Technol· October 2008

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The use of immortalized cell lines in GPCR screening: the good, bad and ugly.
Richard M Eglen, Annette Gilchrist, Terry Reisine

Comb Chem High Throughput Screen· August 2008

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An overview of drug screening using primary and embryonic stem cells.
Richard M Eglen, Annette Gilchrist, Terry Reisine

Comb Chem High Throughput Screen· August 2008

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Current trends in high-throughput screening.
John Sterling, Dejan Bojanic, Richard M Eglen, Stephan Heyse, Berta Strulovici

Assay Drug Dev Technol· August 2008

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The use of AlphaScreen technology in HTS: current status.
Richard M Eglen, Terry Reisine, Philippe Roby, Nathalie Rouleau, Chantal Illy

Curr Chem Genomics· February 2008

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Muscarinic acetylcholine receptors: mutant mice provide new insights for drug development.
Jürgen Wess, Richard M Eglen, Dinesh Gautam

Nat Rev Drug Discov· September 2007

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Emerging concepts of guanine nucleotide-binding protein-coupled receptor (GPCR) function and implications for high throughput screening.
Richard M Eglen, Roger Bosse, Terry Reisine

Assay Drug Dev Technol· June 2007

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Using ligand-induced conformational change to screen for compounds targeting G-protein-coupled receptors.
Brian F O'Dowd, Mohammad Alijaniaram, Xiaodong Ji, Tuan Nguyen, Richard M Eglen

J Biomol Screen· March 2007

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Beta galactosidase complementation: a cell-based luminescent assay platform for drug discovery.
Keith R Olson, Richard M Eglen

Assay Drug Dev Technol· February 2007

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An interview with Richard M. Eglen, Ph.D.
Richard M Eglen

Assay Drug Dev Technol· October 2006

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