Publications by authors named "Richard Isbrucker"

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Clinical and regulatory development strategies for GBS vaccines intended for maternal immunisation in low- and middle-income countries.
Kirsty Le Doare, Virginia Benassi, Marco Cavaleri, Godwin Enwere, Birgitte Giersing, Richard Isbrucker

Vaccine· June 2025

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WHO Workshop Report: Regulatory Science to Inform Clinical Pathways for Shigella Vaccines Intended for Use in Children in Low- and Middle-Income Countries.
Robert W Kaminski, Patricia B Pavlinac, James A Platts-Mills, Elizabeth T Rogawski McQuade, William P Hausdorff, Richard A Isbrucker

Vaccines (Basel)· April 2025

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Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Summary of NC3Rs final report to WHO Expert Committee for Biological Standardisation.
Elliot Lilley, Richard Isbrucker, Anthony Holmes

Biologicals· February 2025

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Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Reports from a series of NC3Rs stakeholder workshops.
Elliot Lilley, Richard Isbrucker, Anthony Holmes

Biologicals· February 2025

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Clinical and regulatory development strategies for Shigella vaccines intended for children younger than 5 years in low-income and middle-income countries.
Birgitte K Giersing, Richard Isbrucker, David C Kaslow, Marco Cavaleri, Norman Baylor

Lancet Glob Health· November 2023

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Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Responses from a survey of National Control Laboratories and National Regulatory Authorities.
Elliot Lilley, Martijn Bruysters, Pradip Das, Simeon Gill, Richard Isbrucker

Biologicals· November 2023

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Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Responses from a survey of vaccines and biological therapeutics manufacturers.
Elliot Lilley, Emmanuelle Coppens, Pradip Das, Francis Galaway, Richard Isbrucker

Biologicals· February 2023

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Methodology for a correlate of protection for group B Streptococcus: Report from the Bill & Melinda Gates Foundation workshop held on 10 and 11 February 2021.
Peter B Gilbert, Richard Isbrucker, Nick Andrews, David Goldblatt, Paul T Heath

Vaccine· July 2022

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Pivotal Vaccine Efficacy Trials-Study Design Considerations from a Vaccine Trial Design Working Group.
Patricia B Pavlinac, Elizabeth T Rogawski McQuade, James A Platts-Mills, Karen L Kotloff, Carolyn Deal, Richard A Isbrucker

Vaccines (Basel)· March 2022

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Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals.
Elliot Lilley, Richard Isbrucker, Ian Ragan, Anthony Holmes

Biologicals· November 2021

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Results of an international transferability study of the BINACLE (binding and cleavage) assay for in vitro detection of tetanus toxicity.
Heike A Behrensdorf-Nicol, Ursula Bonifas, Richard Isbrucker, Hanspeter Ottiger, Robert Tierney

Biologicals· July 2014

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Report on the international workshop on alternatives to the murine histamine sensitization test (HIST) for acellular pertussis vaccines: state of the science and the path forward.
Richard Isbrucker, Juan Arciniega, Richard McFarland, Jean-Michel Chapsal, Dorothy Xing

Biologicals· March 2014

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Non-animal replacement methods for human vaccine potency testing: state of the science and future directions.
Richard McFarland, Daniela Verthelyi, Warren Casey, Juan Arciniega, Richard Isbrucker

Procedia Vaccinol· December 2011

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Leiodermatolide, a potent antimitotic macrolide from the marine sponge Leiodermatium sp.
Ian Paterson, Stephen M Dalby, Jill C Roberts, Guy J Naylor, Esther A Guzmán, Richard Isbrucker

Angew Chem Int Ed Engl· March 2011

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Study of aggregation, denaturation and reduction of interferon alpha-2 products by size-exclusion high-performance liquid chromatography with fluorescence detection and biological assays.
Abebaw Diress, Barry Lorbetskie, Louise Larocque, Xuguang Li, Matthew Alteen, Richard Isbrucker

J Chromatogr A· May 2010

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Modified binding assay for improved sensitivity and specificity in the detection of residual pertussis toxin in vaccine preparations.
Richard A Isbrucker, Alex Bliu, Fiona Prior

Vaccine· March 2010

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Early effects of lasonolide a on pancreatic cancer cells.
Richard A Isbrucker, Esther A Guzmán, Tara P Pitts, Amy E Wright

J Pharmacol Exp Ther· November 2009

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Plakolide A, a new gamma-lactone from the marine sponge Plakortis sp.
Sarath P Gunasekera, Richard A Isbrucker, Ross E Longley, Amy E Wright, Shirley A Pomponi

J Nat Prod· January 2004

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Tubulin polymerizing activity of dictyostatin-1, a polyketide of marine sponge origin.
Richard A Isbrucker, Jennifer Cummins, Shirley A Pomponi, Ross E Longley, Amy E Wright

Biochem Pharmacol· July 2003

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Semisynthetic analogues of the microtubule-stabilizing agent discodermolide: preparation and biological activity.
Sarath P Gunasekera, Ross E Longley, Richard A Isbrucker

J Nat Prod· December 2002

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Five new discodermolide analogues from the marine sponge Discodermia species.
Sarath P Gunasekera, Gopal K Paul, Ross E Longley, Richard A Isbrucker, Shirley A Pomponi

J Nat Prod· November 2002

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