Publications by authors named "Richard M Shepard"

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Novel quinoline derivatives as inhibitors of bacterial DNA gyrase and topoisomerase IV.
Mark J Mitton-Fry, Steven J Brickner, Judith C Hamel, Lori Brennan, Jeffrey M Casavant, Richard M Shepard

Bioorg Med Chem Lett· May 2013

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Discovery, synthesis and SAR of azinyl- and azolylbenzamides antagonists of the P2X₇ receptor.
Chakrapani Subramanyam, Allen J Duplantier, Mark A Dombroski, Shang-Poa Chang, Christopher A Gabel, Richard M Shepard

Bioorg Med Chem Lett· September 2011

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A rational chemical intervention strategy to circumvent bioactivation liabilities associated with a nonpeptidyl thrombopoietin receptor agonist containing a 2-amino-4-arylthiazole motif.
Amit S Kalgutkar, James Driscoll, Sabrina X Zhao, Gregory S Walker, Richard M Shepard

Chem Res Toxicol· December 2007

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Pyrimidine benzamide-based thrombopoietin receptor agonists.
Lawrence A Reiter, Chakrapani Subramanyam, Emilio J Mangual, Christopher S Jones, Marc I Smeets, Richard M Shepard

Bioorg Med Chem Lett· October 2007

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Piperazinyl CCR1 antagonists--optimization of human liver microsome stability.
Matthew F Brown, Kevin B Bahnck, Laura C Blumberg, William H Brissette, Sara A Burrell, Richard M Shepard

Bioorg Med Chem Lett· June 2007

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The human specific CCR1 antagonist CP-481,715 inhibits cell infiltration and inflammatory responses in human CCR1 transgenic mice.
Ronald P Gladue, Susan H Cole, Marsha L Roach, Laurie A Tylaska, Robin T Nelson, Richard M Shepard

J Immunol· March 2006

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Novel CCR1 antagonists with improved metabolic stability.
Matthew F Brown, Mike Avery, William H Brissette, J H Chang, Kevin Colizza, Richard M Shepard

Bioorg Med Chem Lett· May 2004

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CP-481,715, a potent and selective CCR1 antagonist with potential therapeutic implications for inflammatory diseases.
Ronald P Gladue, Laurie A Tylaska, William H Brissette, Paul D Lira, John C Kath, Richard M Shepard

J Biol Chem· October 2003

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