Publications by authors named "Richard Meldau"

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Accuracy of VIDAS® TB-IGRA in TB patients and individuals with different thresholds of exposure.
Delia Goletti, Niaz Banaei, Rahul Batra, Anne Emmanuelle Berger, Azra Blazevic, Richard Meldau

Int J Infect Dis· December 2025

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Reply to Adzemovic et al.
Philippa Randall, Junior Mutsvangwa, Marriott Nliwasa, Lindsay Wilson, Brandon Reyneke, Richard Meldau

Open Forum Infect Dis· May 2025

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Autologous Human Dendritic Cells from XDR-TB Patients Polarize a Th1 Response Which Is Bactericidal to .
Rolanda Londt, Lynn Semple, Aliasgar Esmail, Anil Pooran, Richard Meldau

Microorganisms· February 2025

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Utility of Cerebrospinal Fluid Unstimulated Interferon-Gamma (IRISA-TB) as a Same-Day Test for Tuberculous Meningitis in a Tuberculosis-Endemic, Resource-Poor Setting.
Philippa Randall, Junior Mutsvangwa, Marriott Nliwasa, Lindsay Wilson, Beauty Makamure, Richard Meldau

Open Forum Infect Dis· September 2024

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SARS-CoV-2 Viral Replication Persists in the Human Lung for Several Weeks after Symptom Onset.
Michele Tomasicchio, Shameem Jaumdally, Lindsay Wilson, Andrea Kotze, Lynn Semple, Richard Meldau

Am J Respir Crit Care Med· April 2024

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Comparison of two diagnostic intervention packages for community-based active case finding for tuberculosis: an open-label randomized controlled trial.
Aliasgar Esmail, Philippa Randall, Suzette Oelofse, Michele Tomasicchio, Anil Pooran, Richard Meldau

Nat Med· April 2023

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Economic evaluation of microbiological and host biomarker-based tests for the diagnosis of pleural tuberculosis in a high burden setting.
Anil Pooran, Philippa Randall, Richard Meldau, Rebeng Maine, Aliasgar Esmail

J Thorac Dis· September 2022

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Differential RD-1-specific IFN-γ host responses to diverse Mycobacterium tuberculosis strains in HIV-uninfected persons may be explained by genotypic variation in the ESX-1 region.
Michele Tomasicchio, Jason Limberis, Ruben van der Merwe, Rachael Jacobson, Richard Meldau

Int J Infect Dis· July 2020

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Comparison of Xpert MTB/RIF (G4) and Xpert Ultra, including trace readouts, for the diagnosis of pulmonary tuberculosis in a TB and HIV endemic setting.
Aliasgar Esmail, Michele Tomasicchio, Richard Meldau, Edson Makambwa, Keertan Dheda

Int J Infect Dis· June 2020

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A Human Lung Challenge Model to Evaluate the Safety and Immunogenicity of PPD and Live Bacillus Calmette-Guérin.
Malika Davids, Anil Pooran, Clemens Hermann, Lynelle Mottay, Fawziyah Thompson, Richard Meldau

Am J Respir Crit Care Med· May 2020

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Same-Day Tools, Including Xpert Ultra and IRISA-TB, for Rapid Diagnosis of Pleural Tuberculosis: a Prospective Observational Study.
Richard Meldau, Philippa Randall, Anil Pooran, Jason Limberis, Edson Makambwa

J Clin Microbiol· September 2019

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The Injectable Contraceptive Medroxyprogesterone Acetate Attenuates Mycobacterium tuberculosis-Specific Host Immunity Through the Glucocorticoid Receptor.
Michele Tomasicchio, Malika Davids, Anil Pooran, Grant Theron, Liezel Smith, Richard Meldau

J Infect Dis· April 2019

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An autologous dendritic cell vaccine polarizes a Th-1 response which is tumoricidal to patient-derived breast cancer cells.
Michele Tomasicchio, Lynn Semple, Aliasgar Esmail, Richard Meldau, Philippa Randall

Cancer Immunol Immunother· January 2019

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Early morning urine collection to improve urinary lateral flow LAM assay sensitivity in hospitalised patients with HIV-TB co-infection.
Phindile Gina, Philippa J Randall, Tapuwa E Muchinga, Anil Pooran, Richard Meldau

BMC Infect Dis· May 2017

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The diagnostic accuracy of pericardial and urinary lipoarabinomannan (LAM) assays in patients with suspected tuberculous pericarditis.
Shaheen Pandie, Jonathan G Peter, Zita S Kerbelker, Richard Meldau, Grant Theron

Sci Rep· September 2016

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Xpert MTB/RIF Results in Patients With Previous Tuberculosis: Can We Distinguish True From False Positive Results?
Grant Theron, Rouxjeane Venter, Greg Calligaro, Liezel Smith, Jason Limberis, Richard Meldau

Clin Infect Dis· April 2016

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In Vivo Molecular Dissection of the Effects of HIV-1 in Active Tuberculosis.
Lucy C K Bell, Gabriele Pollara, Mellissa Pascoe, Gillian S Tomlinson, Rannakoe J Lehloenya, Richard Meldau

PLoS Pathog· March 2016

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Impact of correcting the lymphocyte count to improve the sensitivity of TB antigen-specific peripheral blood-based quantitative T cell assays (T-SPOT.(®)TB and QFT-GIT).
Richard N van Zyl-Smit, Rannakoe J Lehloenya, Richard Meldau, Keertan Dheda

J Thorac Dis· March 2016

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Burden of tuberculosis in intensive care units in Cape Town, South Africa, and assessment of the accuracy and effect on patient outcomes of the Xpert MTB/RIF test on tracheal aspirate samples for diagnosis of pulmonary tuberculosis: a prospective burden of disease study with a nested randomised controlled trial.
Gregory L Calligaro, Grant Theron, Hoosain Khalfey, Jonathan Peter, Richard Meldau

Lancet Respir Med· August 2015

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Determinants of PCR performance (Xpert MTB/RIF), including bacterial load and inhibition, for TB diagnosis using specimens from different body compartments.
Grant Theron, Jonny Peter, Greg Calligaro, Richard Meldau, Colleen Hanrahan

Sci Rep· July 2014

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Diagnostic accuracy of quantitative PCR (Xpert MTB/RIF) for tuberculous pericarditis compared to adenosine deaminase and unstimulated interferon-γ in a high burden setting: a prospective study.
Shaheen Pandie, Jonathan G Peter, Zita S Kerbelker, Richard Meldau, Grant Theron

BMC Med· June 2014

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Cigarette smoke impairs cytokine responses and BCG containment in alveolar macrophages.
Richard N van Zyl-Smit, Anke Binder, Richard Meldau, Patricia L Semple, Alicia Evans

Thorax· April 2014

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Comparison of same day diagnostic tools including Gene Xpert and unstimulated IFN-γ for the evaluation of pleural tuberculosis: a prospective cohort study.
Richard Meldau, Jonny Peter, Grant Theron, Greg Calligaro, Brian Allwood

BMC Pulm Med· April 2014

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Accuracy and impact of Xpert MTB/RIF for the diagnosis of smear-negative or sputum-scarce tuberculosis using bronchoalveolar lavage fluid.
Grant Theron, Jonny Peter, Richard Meldau, Hoosain Khalfey, Phindile Gina

Thorax· November 2013

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Correlation of mycobacterium tuberculosis specific and non-specific quantitative Th1 T-cell responses with bacillary load in a high burden setting.
Grant Theron, Jonny Peter, Laura Lenders, Richard van Zyl-Smit, Richard Meldau

PLoS One· December 2012

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