Publications by authors named "Richard Treisman"

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MRTF-dependent cytoskeletal dynamics drive efficient cell cycle progression.
Julie C Nielsen, Maria Benito-Jardon, Noel Christo Petrela, Jessica Diring, Sofie Bellamy, Richard Treisman

J Cell Sci· December 2025

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PDZ-directed substrate recruitment is the primary determinant of specific 4E-BP1 dephosphorylation by PP1-Neurabin.
Roman O Fedoryshchak, Karim El-Bouri, Dhira Joshi, Stephane Mouilleron, Richard Treisman

Elife· June 2025

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PP1/PNUTS phosphatase binds the restrictor complex and stimulates RNA Pol II transcription termination.
Benjamin Erickson, Roman Fedoryshchak, Nova Fong, Ryan Sheridan, Keira Y Larson, Richard Treisman

Cell Rep· May 2025

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IL-2 delivery to CD8 T cells during infection requires MRTF/SRF-dependent gene expression and cytoskeletal dynamics.
Diane Maurice, Patrick Costello, Jessica Diring, Francesco Gualdrini, Bruno Frederico, Richard Treisman

Nat Commun· September 2024

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Mutation in PHACTR1 associated with multifocal epilepsy with infantile spasms and hypsarrhythmia.
Andrey V Marakhonov, Magdalena Přechová, Fedor A Konovalov, Alexandra Yu Filatova, Maria A Zamkova, Richard Treisman

Clin Genet· May 2021

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Molecular basis for substrate specificity of the Phactr1/PP1 phosphatase holoenzyme.
Roman O Fedoryshchak, Magdalena Přechová, Abbey M Butler, Rebecca Lee, Nicola O'Reilly, Richard Treisman

Elife· September 2020

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RPEL-family rhoGAPs link Rac/Cdc42 GTP loading to G-actin availability.
Jessica Diring, Stephane Mouilleron, Neil Q McDonald, Richard Treisman

Nat Cell Biol· July 2019

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ERK Signaling Controls Innate-like CD8 T Cell Differentiation via the ELK4 (SAP-1) and ELK1 Transcription Factors.
Diane Maurice, Patrick Costello, Mathew Sargent, Richard Treisman

J Immunol· September 2018

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Mutual dependence of the MRTF-SRF and YAP-TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics.
Charles T Foster, Francesco Gualdrini, Richard Treisman

Genes Dev· December 2017

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A Novel Approach to Data Collection for Difficult Structures: Data Management for Large Numbers of Crystals with the BLEND Software.
Anastasia Mylona, Stephen Carr, Pierre Aller, Isabel Moraes, Richard Treisman

Crystals (Basel)· August 2017

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ERK-Induced Activation of TCF Family of SRF Cofactors Initiates a Chromatin Modification Cascade Associated with Transcription.
Cyril Esnault, Francesco Gualdrini, Stuart Horswell, Gavin Kelly, Aengus Stewart, Richard Treisman

Mol Cell· March 2017

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Local delivery of novel MRTF/SRF inhibitors prevents scar tissue formation in a preclinical model of fibrosis.
Cynthia Yu-Wai-Man, Bradley Spencer-Dene, Richard M H Lee, Kim Hutchings, Erika M Lisabeth, Richard Treisman

Sci Rep· March 2017

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SRF Co-factors Control the Balance between Cell Proliferation and Contractility.
Francesco Gualdrini, Cyril Esnault, Stuart Horswell, Aengus Stewart, Nik Matthews, Richard Treisman

Mol Cell· December 2016

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Opposing effects of Elk-1 multisite phosphorylation shape its response to ERK activation.
Anastasia Mylona, Francois-Xavier Theillet, Charles Foster, Tammy M Cheng, Francesc Miralles, Richard Treisman

Science· October 2016

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Phosphorylation acts positively and negatively to regulate MRTF-A subcellular localisation and activity.
Richard Panayiotou, Francesc Miralles, Rafal Pawlowski, Jessica Diring, Helen R Flynn, Richard Treisman

Elife· June 2016

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Repression of SRF target genes is critical for Myc-dependent apoptosis of epithelial cells.
Katrin E Wiese, Heidi M Haikala, Björn von Eyss, Elmar Wolf, Cyril Esnault, Richard Treisman

EMBO J· June 2015

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MRTF-SRF signaling is required for seeding of HSC/Ps in bone marrow during development.
Patrick Costello, Mathew Sargent, Diane Maurice, Cyril Esnault, Katie Foster, Richard Treisman

Blood· February 2015

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RNA export factor Ddx19 is required for nuclear import of the SRF coactivator MKL1.
Eeva Kaisa Rajakylä, Tiina Viita, Salla Kyheröinen, Guillaume Huet, Richard Treisman

Nat Commun· January 2015

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The role of the MRTF-A/SRF pathway in ocular fibrosis.
Cynthia Yu-Wai-Man, Richard Treisman, Maryse Bailly, Peng Tee Khaw

Invest Ophthalmol Vis Sci· July 2014

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Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts.
Cyril Esnault, Aengus Stewart, Francesco Gualdrini, Phil East, Stuart Horswell, Richard Treisman

Genes Dev· May 2014

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Shedding light on nuclear actin dynamics and function.
Richard Treisman

Trends Biochem Sci· August 2013

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Building better institutions.
Paul Nurse, Richard Treisman, Jim Smith

Science· July 2013

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Blood-borne circadian signal stimulates daily oscillations in actin dynamics and SRF activity.
Alan Gerber, Cyril Esnault, Gregory Aubert, Richard Treisman, François Pralong

Cell· January 2013

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G-actin regulates the shuttling and PP1 binding of the RPEL protein Phactr1 to control actomyosin assembly.
Maria Wiezlak, Jessica Diring, Jasmine Abella, Stephane Mouilleron, Michael Way, Richard Treisman

J Cell Sci· December 2012

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Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity.
Stephane Mouilleron, Maria Wiezlak, Nicola O'Reilly, Richard Treisman, Neil Q McDonald

Structure· November 2012

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