Publications by authors named "Richard Trilles"

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A cationic amphiphilic drug synergizes with strobilurin fungicides to control fungal-borne plant diseases.
Bradley Laflamme, Christopher Blackman, Mackenzie Loranger, Richard Trilles, Kalina Doytchinova-Weil

Cell Chem Biol· June 2025

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Synthesis of Neocannabinoids Using Controlled Friedel-Crafts Reactions.
Alexandra M Millimaci, Richard V Trilles, James H McNeely, Lauren E Brown, Aaron B Beeler

J Org Chem· September 2023

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Fungal-Selective Resorcylate Aminopyrazole Hsp90 Inhibitors: Optimization of Whole-Cell Anticryptococcal Activity and Insights into the Structural Origins of Cryptococcal Selectivity.
Paul T Marcyk, Emmanuelle V LeBlanc, Douglas A Kuntz, Alice Xue, Francisco Ortiz, Richard Trilles

J Med Chem· January 2021

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An oxindole efflux inhibitor potentiates azoles and impairs virulence in the fungal pathogen Candida auris.
Kali R Iyer, Kaddy Camara, Martin Daniel-Ivad, Richard Trilles, Sheila M Pimentel-Elardo

Nat Commun· December 2020

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Discovery of Macrocyclic Inhibitors of Apurinic/Apyrimidinic Endonuclease 1.
Richard Trilles, Dmitri Beglov, Qiujia Chen, Hongzhen He, Randall Wireman

J Med Chem· February 2019

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Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus.
Luke Whitesell, Nicole Robbins, David S Huang, Catherine A McLellan, Tanvi Shekhar-Guturja, Richard Trilles

Nat Commun· January 2019

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High-throughput Screening in Larval Zebrafish Identifies Novel Potent Sedative-hypnotics.
Xiaoxuan Yang, Youssef Jounaidi, Jennifer B Dai, Francisco Marte-Oquendo, Elizabeth S Halpin, Richard Trilles

Anesthesiology· September 2018

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Dihydropyrimidine-Thiones and Clioquinol Synergize To Target β-Amyloid Cellular Pathologies through a Metal-Dependent Mechanism.
Daniel F Tardiff, Lauren E Brown, Xiaohui Yan, Richard Trilles, Nathan T Jui

ACS Chem Neurosci· September 2017

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Discovery of new piperidine amide triazolobenzodiazepinones as intestinal-selective CCK1 receptor agonists.
Kimberly O Cameron, Elena E Beretta, Yue Chen, Margaret Chu-Moyer, Dilinie Fernando, Richard V Trilles

Bioorg Med Chem Lett· April 2012

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Discovery of new antimalarial chemotypes through chemical methodology and library development.
Lauren E Brown, Ken Chih-Chien Cheng, Wan-Guo Wei, Pingwei Yuan, Peng Dai, Richard Trilles

Proc Natl Acad Sci U S A· April 2011

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N-benzylimidazole carboxamides as potent, orally active stearoylCoA desaturase-1 inhibitors.
Karen A Atkinson, Elena E Beretta, Janice A Brown, Mayda Castrodad, Yue Chen, Richard Trilles

Bioorg Med Chem Lett· March 2011

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Focused library approach for identification of new N-acylphenylalanines as VCAM/VLA-4 antagonists.
Li Chen, Richard Trilles, Dorota Miklowski, Tai-Nan Huang, David Fry

Bioorg Med Chem Lett· June 2002

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N-acyl-L-phenylalanine derivatives as potent VLA-4 antagonists that mimic a cyclic peptide conformation.
Li Chen, Jefferson Tilley, Richard V Trilles, Weiya Yun, David Fry

Bioorg Med Chem Lett· January 2002

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