Publications by authors named "Rick Finch"

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Profiling the Preclinical Pharmacokinetics and Biodistribution of a Platinum(IV)-Based Oxaliplatin Prodrug OxaliTEX and Their Significance to Antitumor Response.
Guangan He, Gregory D Thiabaud, Kathryn A Shelton, Luke J Segura, Jonathan F Arambula, Rick A Finch

Mol Pharm· December 2025

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Anti-tumor activity of camptothecin analog conjugate of an RSPO4-based peptibody targeting LGR4/5/6 in preclinical models of colorectal cancer.
Yukimatsu Toh, Ling Wu, Jianghua Tu, Zhengdong Liang, Adela M Aldana, Rick A Finch

Br J Cancer· November 2025

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Engineered exosomes with Kras specific siRNA in pancreatic cancer: a phase I study with immunological correlates.
Valerie S Kalluri, Brandon G Smaglo, Krishnan K Mahadevan, Michelle L Kirtley, Kathleen M McAndrews, Rick Finch

Nat Commun· September 2025

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KRAS -Specific Targeting with Engineered Exosomes Reprograms the Immune Microenvironment to Enable Efficacy of Immune Checkpoint Therapy in PDAC Patients.
Valerie S LeBleu, Brandon G Smaglo, Krishnan K Mahadevan, Michelle L Kirtley, Kathleen M McAndrews, Rick Finch

medRxiv· March 2025

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Anti-tumor activity of camptothecin analog conjugate of a RSPO4-based peptibody targeting LGR4/5/6 in preclinical models of colorectal cancer.
Yukimatsu Toh, Ling Wu, Jianghua Tu, Zhengdong Liang, Adela M Aldana, Rick A Finch

bioRxiv· January 2025

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Oxaliplatin Pt(IV) prodrugs conjugated to gadolinium-texaphyrin as potential antitumor agents.
Grégory Thiabaud, Guangan He, Sajal Sen, Kathryn A Shelton, Wallace B Baze, Rick Finch

Proc Natl Acad Sci U S A· March 2020

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Preclinical Evaluation of the Short-Term Toxicity of 4-(N)-Docosahexaenoyl 2´, 2´- Difluorodeoxycytidine (DHA-dFdC).
Solange Valdes, Youssef W Naguib, Rick A Finch, Wallace B Baze, Christopher A Jolly

Pharm Res· June 2017

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Antitumor sulfonylhydrazines: design, structure-activity relationships, resistance mechanisms, and strategies for improving therapeutic utility.
Krishnamurthy Shyam, Philip G Penketh, Raymond P Baumann, Rick A Finch, Rui Zhu

J Med Chem· May 2015

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Triplex-forming oligonucleotides targeting c-MYC potentiate the anti-tumor activity of gemcitabine in a mouse model of human cancer.
Stephen B Boulware, Laura A Christensen, Howard Thames, Lezlee Coghlan, Karen M Vasquez, Rick A Finch

Mol Carcinog· September 2014

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5-Fluorocytosine derivatives as inhibitors of deoxycytidine kinase.
James E Tarver, Theodore C Jessop, Marianne Carlsen, David J Augeri, Qinghong Fu, Rick Finch

Bioorg Med Chem Lett· December 2009

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Lead optimization and structure-based design of potent and bioavailable deoxycytidine kinase inhibitors.
Theodore C Jessop, James E Tarver, Marianne Carlsen, Amy Xu, Jason P Healy, Rick Finch

Bioorg Med Chem Lett· December 2009

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Targeting oncogenes to improve breast cancer chemotherapy.
Laura A Christensen, Rick A Finch, Adam J Booker, Karen M Vasquez

Cancer Res· April 2006

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Age-related differences in vincristine toxicity and biodistribution in wild-type and transporter-deficient mice.
Toshinari Muramatsu, Dennis R Johnson, Rick A Finch, Linda K Johnson, Janine J Leffert

Oncol Res· January 2005

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Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Brian P Zambrowicz, Alejandro Abuin, Ramiro Ramirez-Solis, Lizabeth J Richter, James Piggott, Rick A Finch

Proc Natl Acad Sci U S A· November 2003

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Comparative study of the importance of multidrug resistance-associated protein 1 and P-glycoprotein to drug sensitivity in immortalized mouse embryonic fibroblasts.
Z Ping Lin, Dennis R Johnson, Rick A Finch, Martin G Belinsky, Gary D Kruh

Mol Cancer Ther· October 2002

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mdmx is a negative regulator of p53 activity in vivo.
Rick A Finch, Dorit B Donoviel, David Potter, Min Shi, Amy Fan

Cancer Res· June 2002

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Human XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortions.
Karen M Vasquez, Jesper Christensen, Lei Li, Rick A Finch, Peter M Glazer

Proc Natl Acad Sci U S A· April 2002

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