Publications by authors named "Rick Van Leeuwen"

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Sex Differences in Prognosis of Patients With Genetic Dilated Cardiomyopathy.
Sophie L V M Stroeks, Marco Merlo, Nerea Mora-Ayestaran, Max Jason, Upasana Tayal, Rick E W van Leeuwen

Circ Heart Fail· November 2025

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CCR2 monocyte-derived macrophages drive cardiac hypertrophy in early HFpEF.
Jana Raman, Steven Simmonds, Ellen Caluwé, Rick van Leeuwen, Caroline Walschap

Am J Physiol Heart Circ Physiol· July 2025

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Genetic Landscape of Patients With Dilated Cardiomyopathy and a Systemic Immune-Mediated Disease.
Sophie L V M Stroeks, Michiel T H M Henkens, Fernando Dominguez, Marco Merlo, Debby M E I Hellebrekers, Rick van Leeuwen

JACC Heart Fail· January 2025

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Cytotoxic T Cells Drive Outcome in Inflammatory Dilated Cardiomyopathy.
Maurits A Sikking, Daniel Harding, Michiel T H M Henkens, Sophie L V M Stroeks, Max F G H M Venner, Rick E W van Leeuwen

Circ Res· December 2024

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Improving diagnosis and risk stratification across the ejection fraction spectrum: the Maastricht Cardiomyopathy registry.
Michiel T H M Henkens, Jerremy Weerts, Job A J Verdonschot, Anne G Raafs, Sophia Stroeks, Rick E W van Leeuwen

ESC Heart Fail· April 2022

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Functional Screening Identifies MicroRNAs as Multi-Cellular Regulators of Heart Failure.
Robin Verjans, Wouter J A Derks, Kerstin Korn, Birte Sönnichsen, Rick E W van Leeuwen

Sci Rep· April 2019

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AntagomiR-103 and -107 Treatment Affects Cardiac Function and Metabolism.
Monika Rech, Annika R Kuhn, Joost Lumens, Paolo Carai, Rick van Leeuwen

Mol Ther Nucleic Acids· March 2019

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SPARC preserves endothelial glycocalyx integrity, and protects against adverse cardiac inflammation and injury during viral myocarditis.
Marieke Rienks, Paolo Carai, Jurgen van Teeffelen, Bart Eskens, Wouter Verhesen, Rick van Leeuwen

Matrix Biol· December 2018

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Osteoglycin prevents the development of age-related diastolic dysfunction during pressure overload by reducing cardiac fibrosis and inflammation.
Sophie Deckx, Ward Heggermont, Paolo Carai, Marieke Rienks, Tom Dresselaers, Rick van Leeuwen

Matrix Biol· March 2018

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MicroRNA-221/222 Family Counteracts Myocardial Fibrosis in Pressure Overload-Induced Heart Failure.
Robin Verjans, Tim Peters, Francisco Javier Beaumont, Rick van Leeuwen, Tessa van Herwaarden

Hypertension· February 2018

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Inhibition of MicroRNA-146a and Overexpression of Its Target Dihydrolipoyl Succinyltransferase Protect Against Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction.
Ward A Heggermont, Anna-Pia Papageorgiou, Annelies Quaegebeur, Sophie Deckx, Paolo Carai, Rick van Leeuwen

Circulation· August 2017

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A novel 72-kDa leukocyte-derived osteoglycin enhances the activation of toll-like receptor 4 and exacerbates cardiac inflammation during viral myocarditis.
Marieke Rienks, Anna Papageorgiou, Kristiaan Wouters, Wouter Verhesen, Rick van Leeuwen

Cell Mol Life Sci· April 2017

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The microRNA-221/-222 cluster balances the antiviral and inflammatory response in viral myocarditis.
Maarten F Corsten, Ward Heggermont, Anna-Pia Papageorgiou, Sophie Deckx, Aloys Tijsma, Rick van Leeuwen

Eur Heart J· November 2015

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Osteoglycin prevents cardiac dilatation and dysfunction after myocardial infarction through infarct collagen strengthening.
Lucas N L Van Aelst, Sandra Voss, Paolo Carai, Rick Van Leeuwen, Davy Vanhoutte

Circ Res· January 2015

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Macrophage microRNA-155 promotes cardiac hypertrophy and failure.
Stephane Heymans, Maarten F Corsten, Wouter Verhesen, Paolo Carai, Rick E W van Leeuwen

Circulation· September 2013

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MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis.
Maarten F Corsten, Anna Papageorgiou, Wouter Verhesen, Paolo Carai, Morten Lindow, Rick van Leeuwen

Circ Res· August 2012

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MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure.
Geert C van Almen, Wouter Verhesen, Rick E W van Leeuwen, Mathijs van de Vrie, Casper Eurlings

Aging Cell· October 2011

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Regulation of cardiac gene expression by KLF15, a repressor of myocardin activity.
Joost J Leenders, Wino J Wijnen, Monika Hiller, Ingeborg van der Made, Viola Lentink, Rick E W van Leeuwen

J Biol Chem· August 2010

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Syndecan-1 amplifies angiotensin II-induced cardiac fibrosis.
Mark W M Schellings, Davy Vanhoutte, Geert C van Almen, Melissa Swinnen, Joost J G Leenders, Rick E W van Leeuwen

Hypertension· February 2010

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miR-133 and miR-30 regulate connective tissue growth factor: implications for a role of microRNAs in myocardial matrix remodeling.
Rudy F Duisters, Anke J Tijsen, Blanche Schroen, Joost J Leenders, Viola Lentink, Rick E van Leeuwen

Circ Res· January 2009

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Absence of SPARC results in increased cardiac rupture and dysfunction after acute myocardial infarction.
Mark W M Schellings, Davy Vanhoutte, Melissa Swinnen, Jack P Cleutjens, Jacques Debets, Rick E W van Leeuwen

J Exp Med· January 2009

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Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy.
Blanche Schroen, Joost J Leenders, Arie van Erk, Anne T Bertrand, Mirjam van Loon, Rick E van Leeuwen

J Exp Med· May 2007

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Imatinib attenuates end-organ damage in hypertensive homozygous TGR(mRen2)27 rats.
Mark W M Schellings, Marcus Baumann, Rick E W van Leeuwen, Rudy F J J Duisters, Suzanne H P Janssen

Hypertension· March 2006

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Thrombospondin-2 is essential for myocardial matrix integrity: increased expression identifies failure-prone cardiac hypertrophy.
Blanche Schroen, Stephane Heymans, Umesh Sharma, W Matthijs Blankesteijn, Saraswati Pokharel, Rick E W van Leeuwen

Circ Res· September 2004

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Differential effect of simvastatin on activation of Rac(1) vs. activation of the heat shock protein 27-mediated pathway upon oxidative stress, in human smooth muscle cells.
Pascale Nègre-Aminou, Rick E W van Leeuwen, G Christa F van Thiel, Paul van den IJssel, Wilfried W de Jong

Biochem Pharmacol· November 2002

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