Publications by authors named "Ricky Johnstone"

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Discovery and characterisation of VPRBP/DCAF1 kinase inhibitor analogues as microtubular destabilising agents with potent anti-myeloma activity.
Olivia Susanto, Emily Gruber, Cheng Mun Wun, Rheana L Franich, Xiao Ma, Ricky W Johnstone

Mol Cancer Ther· November 2025

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Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia.
Alexander C Lewis, Emily Gruber, Rheana Franich, Jessica Armstrong, Madison J Kelly, Ricky W Johnstone

Cell· November 2025

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A CDK11-dependent RNA polymerase II pause-checkpoint precedes CDK9-mediated transition to transcriptional elongation.
Jennifer R Devlin, Ben Martin, Nenad Bartonicek, Keziah Ting, Zheng Fan, Ricky W Johnstone

Mol Cell· September 2025

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Stem-like memory and precursors of exhausted T cells share a common progenitor defined by ID3 expression.
Catarina Gago da Graça, Amania A Sheikh, Dane M Newman, Lifen Wen, Sining Li, Ricky W Johnstone

Sci Immunol· January 2025

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RNA kinetics influence the response to transcriptional perturbation in leukaemia cell lines.
Izabela Todorovski, Mary-Jane Tsang, Breon Feran, Zheng Fan, Sreeja Gadipally, Ricky W Johnstone

NAR Cancer· December 2024

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Principles of CRISPR-Cas13 mismatch intolerance enable selective silencing of point-mutated oncogenic RNA with single-base precision.
Carolyn Shembrey, Ray Yang, Joshua Casan, Wenxin Hu, Honglin Chen, Ricky W Johnstone

Sci Adv· December 2024

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Mapping the IMiD-dependent cereblon interactome using BioID-proximity labelling.
Matteo Costacurta, Jarrod J Sandow, Belinda Maher, Olivia Susanto, Stephin J Vervoort, Ricky W Johnstone

FEBS J· November 2024

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PRMT1 acts as a suppressor of MHC-I and anti-tumor immunity.
Tirta M Djajawi, Lizzy Pijpers, Akash Srivaths, David Chisanga, Kok Fei Chan, Ricky W Johnstone

Cell Rep· March 2024

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Imran G House, Emily B Derrick, Kevin Sek, Amanda X Y Chen, Jasmine Li, Ricky W Johnstone

Cell Rep· February 2024

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A novel MYB::PAIP1 oncogenic fusion in pediatric blastic plasmacytoid dendritic cell neoplasm (BPDCN) is dependent on BCL2 expression and is sensitive to venetoclax.
Hansen J Kosasih, Gerry Healey, Margs S Brennan, Stefan Bjelosevic, Teresa Sadras, Ricky W Johnstone

Hemasphere· February 2024

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AR eGFP reporter mouse enables elucidation of AR expression dynamics during anti-tumor immune responses.
Kirsten L Todd, Junyun Lai, Kevin Sek, Yu-Kuan Huang, Dane M Newman, Ricky W Johnstone

Nat Commun· November 2023

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Rationally designed chimeric PI3K-BET bromodomain inhibitors elicit curative responses in MYC-driven lymphoma.
Danielle H Oh, Xiao Ma, Simon J Hogg, Jackson He, Conor Kearney, Ricky W Johnstone

Proc Natl Acad Sci U S A· September 2023

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CRISPR-Cas9 screening identifies an IRF1-SOCS1-mediated negative feedback loop that limits CXCL9 expression and antitumor immunity.
Imran G House, Emily B Derrick, Kevin Sek, Amanda X Y Chen, Jasmine Li, Ricky W Johnstone

Cell Rep· August 2023

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Stepwise progression of β-selection during T cell development involves histone deacetylation.
Anchi S Chann, Mirren Charnley, Lucas M Newton, Andrea Newbold, Florian Wiede, Ricky W Johnstone

Life Sci Alliance· January 2023

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Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis.
Isabella Y Kong, Stephanie Trezise, Amanda Light, Izabela Todorovski, Gisela Mir Arnau, Ricky W Johnstone

Cell Death Differ· December 2022

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Inhibition of mutant IDH1 promotes cycling of acute myeloid leukemia stem cells.
Emily Gruber, Joan So, Alexander C Lewis, Rheana Franich, Rachel Cole, Ricky W Johnstone

Cell Rep· August 2022

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Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemia.
Joan So, Alexander C Lewis, Lorey K Smith, Kym Stanley, Rheana Franich, Ricky W Johnstone

EMBO Mol Med· July 2022

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Distinct modulation of IFNγ-induced transcription by BET bromodomain and catalytic P300/CBP inhibition in breast cancer.
Simon J Hogg, Olga Motorna, Conor J Kearney, Emily B Derrick, Imran G House, Ricky W Johnstone

Clin Epigenetics· July 2022

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Epigenetic Activation of Plasmacytoid DCs Drives IFNAR-Dependent Therapeutic Differentiation of AML.
Jessica M Salmon, Izabela Todorovski, Kym L Stanley, Claudia Bruedigam, Conor J Kearney, Ricky W Johnstone

Cancer Discov· June 2022

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The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression.
Lin Xiao, Mawar Karsa, Emma Ronca, Angelika Bongers, Angelika Kosciolek, Ricky W Johnstone

Front Oncol· May 2022

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SFPQ-ABL1 and BCR-ABL1 use different signaling networks to drive B-cell acute lymphoblastic leukemia.
Lauren M Brown, Soroor Hediyeh-Zadeh, Teresa Sadras, Hannah Huckstep, Jarrod J Sandow, Ricky Johnstone

Blood Adv· April 2022

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Targeting transcription cycles in cancer.
Stephin J Vervoort, Jennifer R Devlin, Nicholas Kwiatkowski, Mingxing Teng, Nathanael S Gray, Ricky W Johnstone

Nat Rev Cancer· January 2022

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BET Inhibition Enhances TNF-Mediated Antitumor Immunity.
Lisa C Wellinger, Simon J Hogg, Dane M Newman, Thomas Friess, Daniela Geiss, Ricky W Johnstone

Cancer Immunol Res· January 2022

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A Histone Deacetylase Inhibitor, Panobinostat, Enhances Chimeric Antigen Receptor T-cell Antitumor Effect Against Pancreatic Cancer.
Aesha I Ali, Minyu Wang, Bianca von Scheidt, Pilar M Dominguez, Aaron J Harrison, Ricky W Johnstone

Clin Cancer Res· November 2021

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Regulatory T Cells Shape the Differential Impact of Radiation Dose-Fractionation Schedules on Host Innate and Adaptive Antitumor Immune Defenses.
Joseph Sia, Jim Hagekyriakou, Ioana Chindris, Hassan Albarakati, Trevor Leong, Ricky W Johnstone

Int J Radiat Oncol Biol Phys· October 2021

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