Publications by authors named "Riley Brien"

Claim this Profile
J
Joint analysis of mutations from autism spectrum disorder, schizophrenia, congenital heart disease, and other developmental disorders improves detection power and implicates shared molecular pathways and CNS processes.
Marc Kealhofer, Ruth Brown, Brien P Riley, Tan-Hoang Nguyen

NAR Genom Bioinform· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Psychiatric disorders converge on common pathways but diverge in cellular context, spatial distribution, and directionality of genetic effects.
Worrawat Engchuan, Omar Shanta, Kuldeep Kumar, Jeffrey R MacDonald, Bhooma Thiruvahindrapuram, Brien Riley

medRxiv· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A cross-disorder analysis of CNVs finds novel loci and dose-dependent relationships of genes to psychiatric traits.
Omar Shanta, Marieke Klein, Molly Sacks, Jeffrey R MacDonald, Adam Maihofer, Brien Riley

medRxiv· July 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel multi-omics mendelian randomization method for gene set enrichment and its application to psychiatric disorders.
Huseyin Gedik, Roseann Peterson, Christos Chatzinakos, Mikhail G Dozmorov, Vladimir Vladimirov, Brien P Riley

medRxiv· April 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Improving the discovery of rare variants associated with alcohol problems by leveraging machine learning phenotype prediction and functional information.
Mohammad Ahangari, Amanda Elswick Gentry, Mohammed F Hassan, Tan Hoang Nguyen, Kenneth S Kendler, Brien P Riley

bioRxiv· September 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Relationship between polygenic risk scores and symptom dimensions of schizophrenia and schizotypy in multiplex families with schizophrenia.
Mohammad Ahangari, Daniel Bustamante, Robert Kirkpatrick, Tan-Hoang Nguyen, Brian C Verrelli, Brien P Riley

Br J Psychiatry· July 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Identifying potential risk genes and pathways for neuropsychiatric and substance use disorders using intermediate molecular mediator information.
Huseyin Gedik, Tan Hoang Nguyen, Roseann E Peterson, Christos Chatzinakos, Vladimir I Vladimirov, Brien P Riley

Front Genet· June 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Case-only exome variation analysis of severe alcohol dependence using a multivariate hierarchical gene clustering approach.
Amanda Elswick Gentry, Jeffry C Alexander, Mohammad Ahangari, Roseann E Peterson, Michael F Miles, Brien P Riley

PLoS One· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Integrative Post-Genome-Wide Association Study Analyses Relevant to Psychiatric Disorders: Imputing Transcriptome and Proteome Signals.
Huseyin Gedik, Roseann E Peterson, Brien P Riley, Vladimir I Vladimirov, Silviu-Alin Bacanu

Complex Psychiatry· April 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Large-scale integration of DNA methylation and gene expression array platforms identifies both and relationships.
Eva E Lancaster, Vladimir I Vladimirov, Brien P Riley, Joseph W Landry, Roxann Roberson-Nay

Epigenetics· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Examining the source of increased bipolar disorder and major depressive disorder common risk variation burden in multiplex schizophrenia families.
Mohammad Ahangari, Robert Kirkpatrick, Tan-Hoang Nguyen, Nathan Gillespie, Kenneth S Kendler, Brien P Riley

Schizophrenia (Heidelb)· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Investigating the role of common and rare variants in multiplex multiple sclerosis families reveals an increased burden of common risk variation.
Elif Everest, Mohammad Ahangari, Ugur Uygunoglu, Melih Tutuncu, Alper Bulbul, Brien P Riley

Sci Rep· October 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Genome-wide analysis of schizophrenia and multiple sclerosis identifies shared genomic loci with mixed direction of effects.
Mohammad Ahangari, Elif Everest, Tan-Hoang Nguyen, Brian C Verrelli, Bradley T Webb, Brien P Riley

Brain Behav Immun· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Evaluating the role of common risk variation in the recurrence risk of schizophrenia in multiplex schizophrenia families.
Mohammad Ahangari, Amanda E Gentry, , Tan-Hoang Nguyen, Robert Kirkpatrick, Brien P Riley

Transl Psychiatry· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A serotonergic biobehavioral signature differentiates cocaine use disorder participants administered mirtazapine.
Liangsuo Ma, Kathryn A Cunningham, Noelle C Anastasio, James M Bjork, Brian A Taylor, Brien P Riley

Transl Psychiatry· May 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Vassily Trubetskoy, Antonio F Pardiñas, Ting Qi, Georgia Panagiotaropoulou, Swapnil Awasthi, Niamh Louise O'Brien, Brien P Riley

Nature· April 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders.
Gabriëlla A M Blokland, Jakob Grove, Chia-Yen Chen, Chris Cotsapas, Stuart Tobet, Brien P Riley

Biol Psychiatry· January 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
DECO: a framework for jointly analyzing de novo and rare case/control variants, and biological pathways.
Tan-Hoang Nguyen, Xin He, Ruth C Brown, Bradley T Webb, Kenneth S Kendler, Brien P Riley

Brief Bioinform· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Recruiting for diversity: a pilot test of recruitment strategies for a national alcohol survey with mail-in genetic data collection.
Karen G Chartier, Priscilla Martinez, Cory Cummings, Brien P Riley, Katherine J Karriker-Jaffe

J Community Genet· July 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Increasing the resolution and precision of psychiatric genome-wide association studies by re-imputing summary statistics using a large, diverse reference panel.
Chris Chatzinakos, Donghyung Lee, Na Cai, Vladimir I Vladimirov, Bradley T Webb, Brien P Riley

Am J Med Genet B Neuropsychiatr Genet· January 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
TWAS pathway method greatly enhances the number of leads for uncovering the molecular underpinnings of psychiatric disorders.
Chris Chatzinakos, Foivos Georgiadis, Donghyung Lee, Na Cai, Vladimir I Vladimirov, Brien P Riley

Am J Med Genet B Neuropsychiatr Genet· December 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Assessing the Role of Long Noncoding RNA in Nucleus Accumbens in Subjects With Alcohol Dependence.
John Drake, Gowon O McMichael, Eric Sean Vornholt, Kellen Cresswell, Vernell Williamson, Brien P Riley

Alcohol Clin Exp Res· December 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A large-scale genome-wide association study meta-analysis of cannabis use disorder.
Emma C Johnson, Ditte Demontis, Thorgeir E Thorgeirsson, Raymond K Walters, Renato Polimanti, Brien P Riley

Lancet Psychiatry· December 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
mTADA is a framework for identifying risk genes from de novo mutations in multiple traits.
Tan-Hoang Nguyen, Amanda Dobbyn, Ruth C Brown, Brien P Riley, Joseph D Buxbaum

Nat Commun· June 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Retraction Note: 11,670 whole-genome sequences representative of the Han Chinese population from the CONVERGE project.
Na Cai, Tim B Bigdeli, Warren W Kretzschmar, Yihan Li, Jieqin Liang, Brien Riley

Sci Data· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis