Publications by authors named "Tan-Hoang Nguyen"

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Joint analysis of mutations from autism spectrum disorder, schizophrenia, congenital heart disease, and other developmental disorders improves detection power and implicates shared molecular pathways and CNS processes.
Marc Kealhofer, Ruth Brown, Brien P Riley, Tan-Hoang Nguyen

NAR Genom Bioinform· December 2025

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MIRAGE: A Bayesian statistical method for gene-level rare-variant analysis incorporating functional annotations.
Shengtong Han, Xiaotong Sun, Laura Sloofman, F Kyle Satterstrom, Xizhi Xu, Tan-Hoang Nguyen

Am J Hum Genet· December 2025

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Genome-wide association study of major anxiety disorders in 122,341 European-ancestry cases identifies 58 loci and highlights GABAergic signaling.
Nora I Strom, Brad Verhulst, Silviu-Alin Bacanu, Rosa Cheesman, Kirstin L Purves, Tan-Hoang Nguyen

medRxiv· July 2024

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Improving the discovery of rare variants associated with alcohol problems by leveraging machine learning phenotype prediction and functional information.
Mohammad Ahangari, Amanda Elswick Gentry, Mohammed F Hassan, Tan Hoang Nguyen, Kenneth S Kendler

bioRxiv· September 2023

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Relationship between polygenic risk scores and symptom dimensions of schizophrenia and schizotypy in multiplex families with schizophrenia.
Mohammad Ahangari, Daniel Bustamante, Robert Kirkpatrick, Tan-Hoang Nguyen, Brian C Verrelli

Br J Psychiatry· July 2023

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Identifying potential risk genes and pathways for neuropsychiatric and substance use disorders using intermediate molecular mediator information.
Huseyin Gedik, Tan Hoang Nguyen, Roseann E Peterson, Christos Chatzinakos, Vladimir I Vladimirov

Front Genet· June 2023

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Schizophrenia risk conferred by rare protein-truncating variants is conserved across diverse human populations.
Dongjing Liu, Dara Meyer, Brian Fennessy, Claudia Feng, Esther Cheng, Tan-Hoang Nguyen

Nat Genet· March 2023

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Examining the source of increased bipolar disorder and major depressive disorder common risk variation burden in multiplex schizophrenia families.
Mohammad Ahangari, Robert Kirkpatrick, Tan-Hoang Nguyen, Nathan Gillespie, Kenneth S Kendler

Schizophrenia (Heidelb)· November 2022

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Genome-wide analysis of schizophrenia and multiple sclerosis identifies shared genomic loci with mixed direction of effects.
Mohammad Ahangari, Elif Everest, Tan-Hoang Nguyen, Brian C Verrelli, Bradley T Webb

Brain Behav Immun· August 2022

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Evaluating the role of common risk variation in the recurrence risk of schizophrenia in multiplex schizophrenia families.
Mohammad Ahangari, Amanda E Gentry, , Tan-Hoang Nguyen, Robert Kirkpatrick

Transl Psychiatry· July 2022

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DECO: a framework for jointly analyzing de novo and rare case/control variants, and biological pathways.
Tan-Hoang Nguyen, Xin He, Ruth C Brown, Bradley T Webb, Kenneth S Kendler

Brief Bioinform· September 2021

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mTADA is a framework for identifying risk genes from de novo mutations in multiple traits.
Tan-Hoang Nguyen, Amanda Dobbyn, Ruth C Brown, Brien P Riley, Joseph D Buxbaum

Nat Commun· June 2020

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