Publications by authors named "Rima D Alharthy"

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Dual targeting of neuroblastoma and cholinesterase by morpholino/pyrrolidino-sulfonyl-indole thiosemicarbazones: Synthesis, characterization, enzyme inhibition, cytotoxicity, docking and dynamics studies.
Zahra Batool, Gülbahar Özge Alim Toraman, Furkan Çakır, Gülaçtı Topçu, Parham Taslimi, Rima D Alharthy

Bioorg Chem· December 2025

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A series of 4-thiomorpholinophenyl-thiosemicarbazones as cholinesterase inhibitors with anti-neuroblastoma effects.
Hina Aftab, Furkan Çakır, Gurbet Çelik Turgut, Nastaran Sadeghian, Rima D Alharthy

Bioorg Chem· December 2025

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Synthesis of 6-ethoxyphenyl 4-fluorobenzenesulfonate-tagged thiosemicarbazones as carbonic anhydrase inhibitors: In-vitro and in silico approach.
Iqra Munir, Hina Aftab, Abdul Asim Farooq, Halil Şenol, Parham Taslimi, Rima D Alharthy

Bioorg Med Chem· November 2025

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Design, Synthesis, In Vitro, and In Silico Studies of 5-(Diethylamino)-2-Formylphenyl Naphthalene-2-Sulfonate Based Thiosemicarbazones as Potent Anti-Alzheimer Agents.
Urva Farooq, Muhammad Islam, Zahra Batool, Suraj N Mali, Rahul D Jawarkar, Rima D Alharthy

Arch Pharm (Weinheim)· July 2025

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Synthesis, biological evaluation, and in silico studies of phenyl naphthalene-2-sulfonate derived thiosemicarbazones as potential carbonic anhydrase inhibitors.
Javeria Eshal, Hafiza Zara Tariq, Jing Li, Hina Aftab, Halil Şenol, Rima D Alharthy

Bioorg Chem· February 2025

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Synthesis, and study of novel 1,3-diphenylurea derived Schiff bases as competitive α-glucosidase inhibitors.
Anam Rubbab Pasha, Saeed Ullah, Ajmal Khan, Sobia Ahsan Halim, Javid Hussain, Rima D Alharthy

RSC Adv· September 2024

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Synthesis of the chromone-thiosemicarbazone scaffold as promising α-glucosidase inhibitors: An in vitro and in silico approach toward antidiabetic drug design.
Rima D Alharthy, Sana Khalid, Shamool Fatima, Saeed Ullah, Ajmal Khan

Arch Pharm (Weinheim)· August 2024

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Synthesis, biological evaluation, and molecular modelling of substituted thiazolyl thiourea derivatives: A new class of prolyl oligopeptidase inhibitors.
Saira Naseem, Angelo Oneto, Saeed Ullah, Shamool Fatima, Suraj N Mali, Rima D Alharthy

Int J Biol Macromol· August 2024

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Binding selectivity analysis of AURKs inhibitors through molecular dynamics simulation studies.
Rima D Alharthy, Ghulam Fatima, Numan Yousaf, Muhammad Shaheen Iqbal, Sadia Sattar

PLoS One· December 2023

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Synthesis, biological evaluation, and molecular docking study of chromen-linked hydrazine carbothioamides as potent α-glucosidase inhibitors.
Rabia Basri, Saeed Ullah, Sobia Ahsan Halim, Rima D Alharthy, Umair Rauf

Drug Dev Res· August 2023

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Synthesis of novel 3-hydroxy-2-naphthoic hydrazones as selective chemosensors for cyanide ions.
Rima D Alharthy, Ifra Urooj, Mussarat Tasleem, Muhammad Khalid, Muhammad Adnan Asghar

RSC Adv· May 2023

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Pyrazole derivatives of pyridine and naphthyridine as proapoptotic agents in cervical and breast cancer cells.
Rima D Alharthy, Faisal Rashid, Abida Ashraf, Zahid Shafiq, Steven Ford

Sci Rep· April 2023

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Identification of human phosphoglycerate mutase 1 (PGAM1) inhibitors using hybrid virtual screening approaches.
Numan Yousaf, Rima D Alharthy, Maryam, Iqra Kamal, Muhammad Saleem

PeerJ· April 2023

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Design, Synthesis, and Density Functional Theory Studies of Indole Hydrazones as Colorimetric "Naked Eye" Sensors for F Ions.
Rima D Alharthy, Nadeem Ahmed, Saman Mubarak, Muhammad Yaqub, Muhammad Khalid

ACS Omega· April 2023

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Synthesis, Biological Evaluation, and Molecular Dynamics of Carbothioamides Derivatives as Carbonic Anhydrase II and 15-Lipoxygenase Inhibitors.
Pervaiz Ali Channar, Rima D Alharthy, Syeda Abida Ejaz, Aamer Saeed, Jamshed Iqbal

Molecules· December 2022

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Laboratory Experiments on the In Situ Upgrading of Heavy Crude Oil Using Catalytic Aquathermolysis by Acidic Ionic Liquid.
Rima D Alharthy, Raghda A El-Nagar, Alaa Ghanem

Materials (Basel)· August 2022

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Nucleotide pyrophosphatase/phosphodiesterases (NPPs) including NPP1 and NPP2/ ATX as important drug targets: A patent review (2015-2020).
Sehrish Bano, Mariya Al-Rashida, Rima D Alharthy, Imtiaz Ali Khan, Jamshed Iqbal

Expert Opin Ther Pat· July 2022

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1,3,5-Thiadiazinane thione derivatives as significant urease inhibitors.
Nuzhat Arshad, Mehreen Lateef, Jamshed Hashim, Aisha Anwar, Rima D Alharthy

Pak J Pharm Sci· May 2022

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Development and exploration of novel substituted thiosemicarbazones as inhibitors of aldose reductase via in vitro analysis and computational study.
Aqeel Imran, Muhammad Tariq Shehzad, Syed Jawad Ali Shah, Taha Al Adhami, Mark Laws, Rima D Alharthy

Sci Rep· April 2022

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Folate Conjugated Polyethylene Glycol Probe for Tumor-Targeted Drug Delivery of 5-Fluorouracil.
Shabnam Sarwar, Muhammad Abdul Qadir, Rima D Alharthy, Mahmood Ahmed, Saghir Ahmad

Molecules· March 2022

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Synthesis and Characterization of Imidazolium-Based Ionic Liquids and Evaluating Their Performance as Asphaltene Dispersants.
Alaa Ghanem, Rima D Alharthy, Saad M Desouky, Raghda A El-Nagar

Materials (Basel)· February 2022

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Synthesis, characterization and biological evaluation of indomethacin derived thioureas as purinergic (P2Y, P2Y, P2Y, and P2Y) receptor antagonists.
Sehrish Bano, Ghulam Shabir, Aamer Saeed, Anwar Ul-Hamid, Rima D Alharthy

Bioorg Chem· November 2021

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Fabrication and Characterization of Polypyrrole/Multi-Walled Carbon Nanotubes Thin Films Using Thermal Evaporation.
Alaa Attar, Rima D Alharthy, Mohammed Zwawi, Mohammed Algarni, Faisal Albatati

Polymers (Basel)· November 2021

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A Novel Trace-Level Ammonia Gas Sensing Based on Flexible PAni-CoFeO Nanocomposite Film at Room Temperature.
Rima D Alharthy, Ahmed Saleh

Polymers (Basel)· September 2021

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Toxic and heavy metals contamination assessment in soil and water to evaluate human health risk.
Waqar Ahmad, Rima D Alharthy, Muhammad Zubair, Mahmood Ahmed, Abdul Hameed

Sci Rep· August 2021

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