Publications by authors named "Robel Getachew"

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Flavopiridol Inhibits TGF--Stimulated Biglycan Synthesis by Blocking Linker Region Phosphorylation and Nuclear Translocation of Smad2.
Muhamad A Rostam, Aravindra Shajimoon, Danielle Kamato, Partha Mitra, Terrence J Piva, Robel Getachew

J Pharmacol Exp Ther· April 2018

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Multiple Growth Factors, But Not VEGF, Stimulate Glycosaminoglycan Hyperelongation in Retinal Choroidal Endothelial Cells.
Othman Al Gwairi, Narin Osman, Robel Getachew, Wenhua Zheng, X-L Liang

Int J Biol Sci· November 2017

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An Investigation of Sodium Fusidate and Recombinant Cytochrome P450 Enzymes Inhibition In-Vitro.
John Mishriky, Jacqueline Balassone, Zenah Bashour, Simranjit Kaur, Vini Raman, Robel Getachew

Drug Metab Lett· October 2017

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Evaluation of the potential synergism of imatinib-related poly kinase inhibitors using growth factor stimulated proteoglycan synthesis as a model response.
Rebekah Bernard, Robel Getachew, Danielle Kamato, Lyna Thach, Narin Osman

J Pharm Pharmacol· March 2016

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Protease activated receptor-1 mediated dual kinase receptor transactivation stimulates the expression of glycosaminoglycan synthesizing genes.
Danielle Kamato, Lyna Thach, Robel Getachew, Micah Burch, Morley D Hollenberg

Cell Signal· January 2016

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Transforming growth factor β-mediated site-specific Smad linker region phosphorylation in vascular endothelial cells.
Danielle Kamato, Muhamad Ashraf Rostam, Terence J Piva, Hossein Babaahmadi Rezaei, Robel Getachew

J Pharm Pharmacol· December 2014

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Platelet-derived growth factor-stimulated versican synthesis but not glycosaminoglycan elongation in vascular smooth muscle is mediated via Akt phosphorylation.
Narin Osman, Robel Getachew, Lyna Thach, Haitao Wang, Xiaoying Su

Cell Signal· May 2014

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Atherogenic, fibrotic and glucose utilising actions of glucokinase activators on vascular endothelium and smooth muscle.
Sefaa Al-aryahi, Danielle Kamato, Robel Getachew, Wenhua Zheng, Simon J Potocnik

Cardiovasc Diabetol· April 2014

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Siah2-deficient mice show impaired skin wound repair.
James N Musyoka, Mira C P Liu, Dodie S Pouniotis, Christina S F Wong, David D Bowtell, Robel Getachew

Wound Repair Regen· December 2013

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Smad2-dependent glycosaminoglycan elongation in aortic valve interstitial cells enhances binding of LDL to proteoglycans.
Narin Osman, K Jane Grande-Allen, Mandy L Ballinger, Robel Getachew, Silvana Marasco

Cardiovasc Pathol· September 2013

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(S)-[6]-Gingerol inhibits TGF-β-stimulated biglycan synthesis but not glycosaminoglycan hyperelongation in human vascular smooth muscle cells.
Danielle Kamato, Hossein Babaahmadi Rezaei, Robel Getachew, Lyna Thach, Daniel Guidone

J Pharm Pharmacol· July 2013

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Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells.
Peter J Little, Muhamad Ashraf Rostam, Terrence J Piva, Robel Getachew, Danielle Kamato

J Pharm Pharmacol· July 2013

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Thrombin-mediated proteoglycan synthesis utilizes both protein-tyrosine kinase and serine/threonine kinase receptor transactivation in vascular smooth muscle cells.
Micah L Burch, Robel Getachew, Narin Osman, Mark A Febbraio, Peter J Little

J Biol Chem· March 2013

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Genistein inhibits PDGF-stimulated proteoglycan synthesis in vascular smooth muscle without blocking PDGFβ receptor phosphorylation.
Peter J Little, Robel Getachew, Hossein Babaahmadi Rezaei, Estella Sanchez-Guerrero, Levon M Khachigian

Arch Biochem Biophys· September 2012

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G protein coupled receptor transactivation: extending the paradigm to include serine/threonine kinase receptors.
Micah L Burch, Narin Osman, Robel Getachew, Sefaa Al-Aryahi, Philip Poronnik

Int J Biochem Cell Biol· May 2012

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TGF-β stimulates biglycan core protein synthesis but not glycosaminoglycan chain elongation via Akt phosphorylation in vascular smooth muscle.
Narin Osman, Robel Getachew, Micah Burch, Graeme Lancaster, Rikang Wang

Growth Factors· October 2011

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Endothelin-1 stimulation of proteoglycan synthesis in vascular smooth muscle is mediated by endothelin receptor transactivation of the transforming growth factor-[beta] type I receptor.
Peter J Little, Micah L Burch, Robel Getachew, Sefaa Al-aryahi, Narin Osman

J Cardiovasc Pharmacol· October 2010

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PDGF beta-receptor kinase activity and ERK1/2 mediate glycosaminoglycan elongation on biglycan and increases binding to LDL.
Robel Getachew, Mandy L Ballinger, Micah L Burch, Julianne J Reid, Levon M Khachigian

Endocrinology· September 2010

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Thrombin stimulation of proteoglycan synthesis in vascular smooth muscle is mediated by protease-activated receptor-1 transactivation of the transforming growth factor beta type I receptor.
Micah L Burch, Mandy L Ballinger, Sundy N Y Yang, Robel Getachew, Catherine Itman

J Biol Chem· August 2010

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TGF-beta stimulates biglycan synthesis via p38 and ERK phosphorylation of the linker region of Smad2.
Micah L Burch, Sundy N Y Yang, Mandy L Ballinger, Robel Getachew, Narin Osman

Cell Mol Life Sci· June 2010

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Characterisation of Ki11502 as a potent inhibitor of PDGF beta receptor-mediated proteoglycan synthesis in vascular smooth muscle cells.
Robel Getachew, Mandy L Ballinger, Micah L Burch, Peter J Little, Narin Osman

Eur J Pharmacol· January 2010

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Growth factor-mediated hyper-elongation of glycosaminoglycan chains on biglycan requires transcription and translation.
Sundy N Y Yang, Micah L Burch, Robel Getachew, Mandy L Ballinger, Narin Osman

Arch Physiol Biochem· July 2009

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p38 MAP kinase mediated proteoglycan synthesis as a target for the prevention of atherosclerosis.
Narin Osman, Mandy L Ballinger, Harsha M Dadlani, Robel Getachew, Micah L Burch

Cardiovasc Hematol Disord Drug Targets· December 2008

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Smad and p38 MAP kinase-mediated signaling of proteoglycan synthesis in vascular smooth muscle.
Harsha Dadlani, Mandy L Ballinger, Narin Osman, Robel Getachew, Peter J Little

J Biol Chem· March 2008

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