Publications by authors named "Robert Bast"

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DIRAS3-derived cyclic peptides disrupt KRAS-RAF interaction and KRAS nanoclustering, suppressing KRAS-driven pancreatic and ovarian tumors.
Joshua P Gray, Gamze Bildik, Ha-Neul Kim, Margie N Sutton, Jing Wang, Robert C Bast

iScience· November 2025

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Quantitative proteomics identifies conserved proteins and altered regulation of mucin-16 in low grade serous ovarian cancers.
Christopher M Tarney, Paulette Mhawech-Fauceglia, Jonathan D Ogata, Julie Oliver, Tamara Abulez, Robert C Bast

Clin Proteomics· October 2025

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DIRAS3 Inhibits Ovarian Cancer Cell Growth by Blocking the Fibronectin-Mediated Integrin β1/FAK/AKT Signaling Pathway.
Jing Guo, Janice M Santiago-O'Farrill, Vivian Orellana, Rumeysa Ozyurt, Hailing Yang, Robert C Bast

Cells· August 2025

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GlycoKnow Ovarian: a Glycoprotein-based, Serum Diagnostic to Distinguish Ovarian Cancers from Benign Pelvic Masses.
Daniel Serie, Kaitlynn Moser, Maurice Wong, Khushbu Desai, Chad Pickering, Robert C Bast

medRxiv· June 2025

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CA-125 as a Biomarker in Renal Medullary Carcinoma: Integrated Molecular Profiling, Functional Characterization, and Prospective Clinical Validation.
Sandra L Grimm, Menuka Karki, Kyle A Blum, Jean-Philippe Bertocchio, Rong He, Robert C Bast

Clin Cancer Res· March 2025

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Crizotinib Enhances PARP Inhibitor Efficacy in Ovarian Cancer Cells and Xenograft Models by Inducing Autophagy.
Janice M Santiago-O'Farrill, Alicia Blessing Bollu, Hailing Yang, Vivian Orellana, Marc Pina, Robert C Bast

Mol Cancer Res· September 2024

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A metabolite-based liquid biopsy for detection of ovarian cancer.
Johannes F Fahrmann, Seyyed Mahmood Ghasemi, Chae Y Han, Ranran Wu, Jennifer B Dennison, Robert C Bast

Biomark Res· August 2024

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A novel SIK2 inhibitor SIC-19 exhibits synthetic lethality with PARP inhibitors in ovarian cancer.
Fang Wang, Xuejiao Yu, Jun Qian, Yumin Cao, Shunli Dong, Robert C Bast

Drug Resist Updat· May 2024

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IL-2-free tumor-infiltrating lymphocyte therapy with PD-1 blockade demonstrates potent efficacy in advanced gynecologic cancer.
Jing Guo, Chunyan Wang, Ning Luo, Yuliang Wu, Wei Huang, Robert C Bast

BMC Med· May 2024

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Normal Risk Ovarian Screening Study: 21-Year Update.
Chae Young Han, Karen H Lu, Gwen Corrigan, Alexandra Perez, Sharlene D Kohring, Robert C Bast

J Clin Oncol· April 2024

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DIRAS3 induces autophagy and enhances sensitivity to anti-autophagic therapy in KRAS-driven pancreatic and ovarian carcinomas.
Gamze Bildik, Joshua P Gray, Weiqun Mao, Hailing Yang, Rumeysa Ozyurt, Robert C Bast

Autophagy· March 2024

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Autoantibodies, antigen-autoantibody complexes and antigens complement CA125 for early detection of ovarian cancer.
Chae Young Han, Jacob S Bedia, Wei-Lei Yang, Sarah J Hawley, Lindsay Bergan, Robert C Bast

Br J Cancer· March 2024

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Membrane anchoring of the DIRAS3 N-terminal extension permits tumor suppressor function.
Xiaowen Liang, Sung Yun Jung, Lon Wolf Fong, Gamze Bildik, Joshua P Gray, Robert C Bast

iScience· November 2023

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Amyloid-like p53 as prognostic biomarker in serous ovarian cancer-a study of the OVCAD consortium.
Nicole Heinzl, Elisabeth Maritschnegg, Katarzyna Koziel, Christine Schilhart-Wallisch, Georg Heinze, Robert C Bast

Oncogene· August 2023

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A Blood-Based Metabolite Panel for Distinguishing Ovarian Cancer from Benign Pelvic Masses.
Ehsan Irajizad, Chae Y Han, Joseph Celestino, Ranran Wu, Eunice Murage, Robert C Bast

Clin Cancer Res· November 2022

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Classification of High-Grade Serous Ovarian Cancer Using Tumor Morphologic Characteristics.
Katelyn F Handley, Travis T Sims, Nicholas W Bateman, Deanna Glassman, Katherine I Foster, Robert C Bast

JAMA Netw Open· October 2022

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Structure-Based Design of Stapled Peptides That Bind GABARAP and Inhibit Autophagy.
Hawley Brown, Mia Chung, Alina Üffing, Nefeli Batistatou, Tiffany Tsang, Robert C Bast

J Am Chem Soc· August 2022

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SIK2 promotes ovarian cancer cell motility and metastasis by phosphorylating MYLK.
Xiu Shi, Xuejiao Yu, Juan Wang, Shimin Bian, Qiutong Li, Robert C Bast

Mol Oncol· July 2022

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Directed Evolution of PD-L1-Targeted Affibodies by mRNA Display.
Brian J Grindel, Brian J Engel, Justin N Ong, Anupallavi Srinivasamani, Xiaowen Liang, Robert C Bast

ACS Chem Biol· June 2022

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SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancers.
Zhen Lu, Weiqun Mao, Hailing Yang, Janice M Santiago-O'Farrill, Philip J Rask, Robert C Bast

J Clin Invest· June 2022

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Author Correction: Tuning microtubule dynamics to enhance cancer therapy by modulating FER-mediated CRMP2 phosphorylation.
Yiyan Zheng, Ritika Sethi, Lingegowda S Mangala, Charlotte Taylor, Juliet Goldsmith, Robert C Bast

Nat Commun· June 2022

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Development of a Multiprotein Classifier for the Detection of Early Stage Ovarian Cancer.
Kristin L M Boylan, Ashley Petersen, Timothy K Starr, Xuan Pu, Melissa A Geller, Robert C Bast

Cancers (Basel)· June 2022

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One-Pot, One-Step Synthesis of Drug-Loaded Magnetic Multimicelle Aggregates.
Chang Soo Kim, Dmitry Nevozhay, Rebeca Romero Aburto, Ashok Pehere, Lan Pang, Robert C Bast

Bioconjug Chem· May 2022

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Analysis of serum HE4 levels in various histologic subtypes of epithelial ovarian cancer and other malignant tumors.
Alexandra Blackman, Jessica Mitchell, Rachael Rowswell-Turner, Rakesh Singh, Kyu Kwang Kim, Robert C Bast

Tumour Biol· January 2022

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Next steps in the early detection of ovarian cancer.
Robert C Bast, Chae Young Han, Zhen Lu, Karen H Lu

Commun Med (Lond)· October 2021

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