Publications by authors named "Robert Bostwick"

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High-throughput screening for identification of influenza a inhibitors using a cell-based immunofluorescence assay.
Yohanka Martinez-Gzegozewska, Lynn Rasmussen, N Miranda Nebane, Sara McKellip, Dee Radzieta, Robert Bostwick

Antiviral Res· August 2025

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Discovery of a Chiral 2,4-Substituted Pyrrolo[2,3-]pyrimidine as a Potent, Selective, and Orally Bioavailable LRRK2 Inhibitor.
Omar Moukha-Chafiq, Tuyana Malankhanova, Jacob Valiyaveettil, Vandana Gupta, Hollis Kezar, Robert Bostwick

J Med Chem· May 2025

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4-Substituted-2-Thiazole Amides as Viral Replication Inhibitors of Alphaviruses.
Atefeh Garzan, S Kaleem Ahmed, Nicole N Haese, Gauthami Sulgey, Samuel Medica, Robert Bostwick

J Med Chem· December 2024

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A high-throughput response to the SARS-CoV-2 pandemic.
Lynn Rasmussen, Shalisa Sanders, Melinda Sosa, Sara McKellip, N Miranda Nebane, J Robert Bostwick

SLAS Discov· July 2024

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Targeting EMT using low-dose Teniposide by downregulating ZEB2-driven activation of RNA polymerase I in breast cancer.
Brandon J Metge, Heba Allah M Alsheikh, Sarah C Kammerud, Dongquan Chen, Devika Das, J Robert Bostwick

Cell Death Dis· May 2024

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High-Throughput cell-based immunofluorescence assays against influenza.
Yohanka Martinez-Gzegozewska, Lynn Rasmussen, Sara McKellip, Anna Manuvakhova, N Miranda Nebane, Robert Bostwick

SLAS Discov· January 2024

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Development of small-molecule Tau-SH3 interaction inhibitors that prevent amyloid-β toxicity and network hyperexcitability.
Jonathan R Roth, Travis Rush, Samantha J Thompson, Adam R Aldaher, Trae B Dunn, J Robert Bostwick

Neurotherapeutics· January 2024

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Novel Compound Inhibitors of HIV-1 Vpu.
Carolyn A Robinson, Terri D Lyddon, Hwi Min Gil, David T Evans, Yury V Kuzmichev, Robert Bostwick

Viruses· April 2022

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Fighting SARS-CoV-2 with green seaweed sp. extract: extraction protocol predetermines crude ulvan extract anti-SARS-CoV-2 inhibition properties in Vero-E6 cells assay.
Shai Shefer, Arthur Robin, Alexander Chemodanov, Mario Lebendiker, Robert Bostwick

PeerJ· November 2021

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Identification of Quinolinones as Antivirals against Venezuelan Equine Encephalitis Virus.
Nicole N Haese, Nicholas A May, Sharon Taft-Benz, Omar Moukha-Chafiq, Nikhil Madadi, Robert J Bostwick

Antimicrob Agents Chemother· August 2021

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A small molecule that induces translational readthrough of CFTR nonsense mutations by eRF1 depletion.
Jyoti Sharma, Ming Du, Eric Wong, Venkateshwar Mutyam, Yao Li, Robert J Bostwick

Nat Commun· July 2021

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The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules.
Kirill Gorshkov, Catherine Z Chen, Robert Bostwick, Lynn Rasmussen, Bruce Nguyen Tran

ACS Infect Dis· June 2021

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Pyrimidone inhibitors targeting Chikungunya Virus nsP3 macrodomain by fragment-based drug design.
Sixue Zhang, Atefeh Garzan, Nicole Haese, Robert Bostwick, Yohanka Martinez-Gzegozewska

PLoS One· May 2021

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Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors.
S Kaleem Ahmed, Nicole N Haese, Jaden T Cowan, Vibha Pathak, Omar Moukha-Chafiq, Robert Bostwick

J Med Chem· April 2021

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Development and application of high-throughput screens for the discovery of compounds that disrupt ErbB4 signaling: Candidate cancer therapeutics.
Richard L Cullum, Lauren M Lucas, Jared I Senfeld, John T Piazza, Logan T Neel, Robert Bostwick

PLoS One· February 2021

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Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2.
Catherine Z Chen, Paul Shinn, Zina Itkin, Richard T Eastman, Robert Bostwick

Front Pharmacol· January 2021

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Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2.
Catherine Z Chen, Paul Shinn, Zina Itkin, Richard T Eastman, Robert Bostwick

bioRxiv· August 2020

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The SARS-CoV-2 cytopathic effect is blocked with autophagy modulators.
Kirill Gorshkov, Catherine Z Chen, Robert Bostwick, Lynn Rasmussen, Miao Xu

bioRxiv· May 2020

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Studies on Dibenzylamines as Inhibitors of Venezuelan Equine Encephalitis Virus.
Theresa H Nguyen, Nicole N Haese, Nikhil Madadi, Sanjay Sarkar, Kiley Bonin, Robert Bostwick

ACS Infect Dis· December 2019

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Discovery of novel inhibitors of ribosome biogenesis by innovative high throughput screening strategies.
Catherine E Scull, Yinfeng Zhang, Nichole Tower, Lynn Rasmussen, Indira Padmalayam, Robert Bostwick

Biochem J· August 2019

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High-throughput screening and Bayesian machine learning for copper-dependent inhibitors of Staphylococcus aureus.
Alex G Dalecki, Kimberley M Zorn, Alex M Clark, Sean Ekins, Whitney T Narmore, Robert Bostwick

Metallomics· March 2019

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Identification of Specific and Nonspecific Inhibitors of Bacillus anthracis Type III Pantothenate Kinase (PanK).
Justin A Shapiro, John J Varga, Derek Parsonage, William Walton, Matthew R Redinbo, Robert Bostwick

ChemMedChem· January 2019

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Accelerating Drug Development: Antiviral Therapies for Emerging Viruses as a Model.
Maaike Everts, Tomas Cihlar, J Robert Bostwick, Richard J Whitley

Annu Rev Pharmacol Toxicol· January 2017

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A sensitive virus yield assay for evaluation of Antivirals against Zika Virus.
Scott Goebel, Beth Snyder, Timothy Sellati, Mohammad Saeed, Roger Ptak, Robert Bostwick

J Virol Methods· December 2016

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Discovery of Clinically Approved Agents That Promote Suppression of Cystic Fibrosis Transmembrane Conductance Regulator Nonsense Mutations.
Venkateshwar Mutyam, Ming Du, Xiaojiao Xue, Kim M Keeling, E Lucile White, J Robert Bostwick

Am J Respir Crit Care Med· November 2016

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