Publications by authors named "Robert Bream"

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Learning from the EMA experience: common CMC deficiencies in marketing authorisation applications over the past decade.
Dolores Hernán Pérez de la Ossa, Friederike Haas, Robert N Bream, Evangelos Kotzagiorgis, Klara Tiitso

Drug Discov Today· September 2025

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Regulatory Experiences with Root Causes and Risk Factors for Nitrosamine Impurities in Pharmaceuticals.
Stephen Horne, Matthew D Vera, Laxma R Nagavelli, Vilayat A Sayeed, Laurel Heckman, Robert N Bream

J Pharm Sci· May 2023

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Correction: International Regulatory Collaboration on the Analysis of Nitrosamines in Metformin-Containing Medicines.
David A Keire, Robert Bream, Uwe Wollein, Schmaler-Ripcke, Annette Burchardt

AAPS J· July 2022

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International Regulatory Collaboration on the Analysis of Nitrosamines in Metformin-Containing Medicines.
David A Keire, Robert Bream, Uwe Wollein, Jeannette Schmaler-Ripcke, Annette Burchardt

AAPS J· April 2022

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The EU Response to the Presence of Nitrosamine Impurities in Medicines.
Robin Ruepp, Roland Frötschl, Robert Bream, Maria Filancia, Thomas Girard

Front Med (Lausanne)· November 2021

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Design and Application of a DNA-Encoded Macrocyclic Peptide Library.
Zhengrong Zhu, Alex Shaginian, LaShadric C Grady, Thomas O'Keeffe, Xiangguo E Shi, Robert N Bream

ACS Chem Biol· January 2018

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Radical-mediated reduction of the dithiocarbamate group under tin-free conditions.
Claire McMaster, Robert N Bream, Richard S Grainger

Org Biomol Chem· June 2012

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Asymmetric allylic alkylation of cyclic vinylogous esters and thioesters by Pd-catalyzed decarboxylation of enol carbonate and beta-ketoester substrates.
Barry M Trost, Robert N Bream, Jiayi Xu

Angew Chem Int Ed Engl· May 2006

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Synthesis of the beta 2 agonist (R)-salmeterol using a sequence of supported reagents and scavenging agents.
Robert N Bream, Steven V Ley, Panayiotis A Procopiou

Org Lett· October 2002

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