Publications by authors named "Robert Comley"

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Measuring Dopamine Transporter Availability and Synaptic Density in Parkinson's Disease: A Dual-Tracer Positron Emission Tomography Imaging Study.
Faranak Ebrahimian Sadabad, Tommaso Volpi, Praveen Honhar, Sule Tinaz, Mark Dias, Robert Comley

Mov Disord· December 2025

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An in vivo PET/CT investigation of mitochondrial complex 1, sigma 1, and synaptic vesicle 2 A in patients with amyotrophic lateral sclerosis.
Edoardo R de Natale, Joji P Verghese, Alana Terry, Heather Wilson, Pegah Khosropanah, Robert A Comley

Neurobiol Dis· November 2025

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Machine learning-enhanced screening funnel for clinical trials in Alzheimer's disease.
Scott Gladstein, Liuqing Yang, Dustin Wooten, Xin Huang, Robert Comley

Alzheimers Dement (N Y)· April 2025

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Clinical correlates of dopamine transporter availability in cross-sectional and longitudinal studies with [F]FE-PE2I PET: independent validation with new insights.
Praveen Honhar, Faranak Ebrahimian Sadabad, Sule Tinaz, Jean-Dominique Gallezot, Mark Dias, Robert Comley

Brain Commun· October 2024

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Author Correction: Synaptic loss and its association with symptom severity in Parkinson's disease.
Sophie E Holmes, Praveen Honhar, Sule Tinaz, Mika Naganawa, Ansel T Hilmer, Robert Comley

NPJ Parkinsons Dis· March 2024

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Synaptic loss and its association with symptom severity in Parkinson's disease.
Sophie E Holmes, Praveen Honhar, Sule Tinaz, Mika Naganawa, Ansel T Hilmer, Robert Comley

NPJ Parkinsons Dis· February 2024

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Evaluation of a semi-automated approach for FDG PET image analysis for routine clinical application in patients with multiple myeloma.
Tyler J Wellman, Sarah R Mudd, Kelly N Godby, Dustin W Wooten, Jeremy A Ross, Robert A Comley

Transl Oncol· November 2023

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A Visual Interpretation Algorithm for Assessing Brain Tauopathy with F-MK-6240 PET.
John P Seibyl, Jonathan M DuBois, Annie Racine, Jessica Collins, Qi Guo, Robert Comley

J Nucl Med· March 2023

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[F]BTK-1: A Novel Positron Emission Tomography Tracer for Imaging Bruton's Tyrosine Kinase.
Marc B Skaddan, Dustin W Wooten, Kyle C Wilcox, Martin J Voorbach, David R Reuter, Robert A Comley

Mol Imaging Biol· October 2022

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Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease.
Ashwin V Venkataraman, Ayla Mansur, Gaia Rizzo, Courtney Bishop, Yvonne Lewis, Robert A Comley

Sci Transl Med· August 2022

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A Comparison of Magnetic Resonance Imaging Methods to Assess Multiple Sclerosis Lesions: Implications for Patient Characterization and Clinical Trial Design.
Ewart Mark Haacke, Evanthia Bernitsas, Karthik Subramanian, David Utriainen, Vinay Kumar Palutla, Robert A Comley

Diagnostics (Basel)· December 2021

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Test-retest variability and reference region-based quantification of F-BCPP-EF for imaging mitochondrial complex I in the human brain.
Ayla Mansur, Eugenii A Rabiner, Hideo Tsukada, Robert A Comley, Yvonne Lewis

J Cereb Blood Flow Metab· April 2021

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Basmisanil, a highly selective GABA-α5 negative allosteric modulator: preclinical pharmacology and demonstration of functional target engagement in man.
Joerg F Hipp, Frederic Knoflach, Robert Comley, Theresa M Ballard, Michael Honer

Sci Rep· April 2021

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Synaptic Changes in Parkinson Disease Assessed with in vivo Imaging.
David Matuskey, Sule Tinaz, Kyle C Wilcox, Mika Naganawa, Takuya Toyonaga, Robert A Comley

Ann Neurol· March 2020

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Characterization of 3 PET Tracers for Quantification of Mitochondrial and Synaptic Function in Healthy Human Brain: F-BCPP-EF, C-SA-4503, and C-UCB-J.
Ayla Mansur, Eugenii A Rabiner, Robert A Comley, Yvonne Lewis, Lefkos T Middleton

J Nucl Med· January 2020

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The application of positron emission tomography (PET) imaging in CNS drug development.
Ivonne Suridjan, Robert A Comley, Eugenii A Rabiner

Brain Imaging Behav· April 2019

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Characterization of 3 Novel Tau Radiopharmaceuticals, C-RO-963, C-RO-643, and F-RO-948, in Healthy Controls and in Alzheimer Subjects.
Dean F Wong, Robert A Comley, Hiroto Kuwabara, Paul B Rosenberg, Susan M Resnick

J Nucl Med· December 2018

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Evaluation of F-RO-948 PET for Quantitative Assessment of Tau Accumulation in the Human Brain.
Hiroto Kuwabara, Robert A Comley, Edilio Borroni, Michael Honer, Kelly Kitmiller

J Nucl Med· December 2018

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Kinetic Modeling of the Tau PET Tracer F-AV-1451 in Human Healthy Volunteers and Alzheimer Disease Subjects.
Olivier Barret, David Alagille, Sandra Sanabria, Robert A Comley, Robby M Weimer

J Nucl Med· July 2017

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Quantification of [C]Ro15-4513 GABAα5 specific binding and regional selectivity in humans.
Jim Fm Myers, Robert A Comley, Roger N Gunn

J Cereb Blood Flow Metab· June 2017

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Positron emission tomography measurement of brain MAO-B inhibition in patients with Alzheimer's disease and elderly controls after oral administration of sembragiline.
Stefan Sturm, Anton Forsberg, Stephane Nave, Per Stenkrona, Nicholas Seneca, Robert A Comley

Eur J Nucl Med Mol Imaging· March 2017

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Monoamine oxidase B inhibitor, selegiline, reduces F-THK5351 uptake in the human brain.
Kok Pin Ng, Tharick A Pascoal, Sulantha Mathotaarachchi, Joseph Therriault, Min Su Kang, Robert A Comley

Alzheimers Res Ther· March 2017

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Molecular imaging in oncology drug development.
Sarah R Mudd, Robert A Comley, Mats Bergstrom, Kyle D Holen, Yanping Luo

Drug Discov Today· January 2017

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Early and protective microglial activation in Alzheimer's disease: a prospective study using 18F-DPA-714 PET imaging.
Lorraine Hamelin, Julien Lagarde, Guillaume Dorothée, Claire Leroy, Mickael Labit, Robert A Comley

Brain· April 2016

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Increased arterial inflammation in individuals with stage 3 chronic kidney disease.
Richard A P Takx, Megan H MacNabb, Hamed Emami, Amr Abdelbaky, Parmanand Singh, Robert A Comley

Eur J Nucl Med Mol Imaging· February 2016

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