Publications by authors named "Robert D Combes"

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How viable are alternatives to animal testing in determining the toxicities of therapeutic drugs?
Michael Balls, Jarrod Bailey, Robert D Combes

Expert Opin Drug Metab Toxicol· December 2019

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Electronic cigarettes: can dependable public health policies be developed and applied without relevant and reliable risk assessments?
Michael Balls, Robert D Combes

Altern Lab Anim· November 2018

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Questionable progress in the application of the Three Rs to improve science, human well-being and animal welfare.
Michael Balls, Robert D Combes

Altern Lab Anim· May 2018

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The replacement of animal tests.
Robert D Combes

Altern Lab Anim· May 2018

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The use of in vivo, ex vivo, in vitro, computational models and volunteer studies in vision research and therapy, and their contribution to the Three Rs.
Robert D Combes, Atul B Shah

Altern Lab Anim· July 2016

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On the safety of e-cigarettes: "I can resist anything except temptation".
Robert D Combes, Michael Balls

Altern Lab Anim· December 2015

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A critical assessment of the scientific basis, and implementation, of regulations for the safety assessment and marketing of innovative tobacco-related products.
Robert D Combes, Michael Balls

Altern Lab Anim· September 2015

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Missing, presumed killed in action (or the report that never was).
Robert D Combes

Altern Lab Anim· November 2014

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The Three Rs--opportunities for improving animal welfare and the quality of scientific research.
Robert D Combes, Michael Balls

Altern Lab Anim· September 2014

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Every silver lining has a cloud: the scientific and animal welfare issues surrounding a new approach to the production of transgenic animals.
Robert D Combes, Michael Balls

Altern Lab Anim· May 2014

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A critical review of anaesthetised animal models and alternatives for military research, testing and training, with a focus on blast damage, haemorrhage and resuscitation.
Robert D Combes

Altern Lab Anim· November 2013

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Is phenylbutazone a genotoxic carcinogen? A weight-of-evidence assessment.
Robert D Combes

Altern Lab Anim· July 2013

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The potency testing of botulinum neurotoxin products.
Robert D Combes

Altern Lab Anim· December 2012

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In silico methods for toxicity prediction.
Robert D Combes

Adv Exp Med Biol· May 2012

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The use of integrated and intelligent testing strategies in the prediction of toxic hazard and in risk assessment.
Michael Balls, Robert D Combes, Nirmala Bhogal

Adv Exp Med Biol· May 2012

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New technology for toxicity testing.
Robert D Combes, Michael Balls, Nirmala Bhogal

Adv Exp Med Biol· May 2012

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Cell transformation assays: are we barking up the wrong tree?
Robert D Combes

Altern Lab Anim· May 2012

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Challenges for computational structure-activity modelling for predicting chemical toxicity: future improvements?
Robert D Combes

Expert Opin Drug Metab Toxicol· September 2011

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Integrated testing strategies for toxicity employing new and existing technologies.
Robert D Combes, Michael Balls

Altern Lab Anim· July 2011

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The 'microEST' in vitro test for embryotoxicity - validated and endorsed or not?
Robert David Combes

Toxicol In Vitro· March 2009

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Some thoughts on the use of replacement alternatives for toxicity testing and risk assessment.
Robert D Combes

Arch Toxicol· March 2009

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Applications of 2D descriptors in drug design: a DRAGON tale.
Aliuska Morales Helguera, Robert D Combes, Maykel Pérez González, M Natália D S Cordeiro

Curr Top Med Chem· February 2009

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Quantitative structure carcinogenicity relationship for detecting structural alerts in nitroso-compounds: species: rat; sex: male; route of administration: water.
Aliuska Morales Helguera, M Natália D S Cordeiro, Miguel Angel Cabrera Pérez, Robert D Combes, Maykel Pérez González

Toxicol Appl Pharmacol· September 2008

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QSAR modeling of the rodent carcinogenicity of nitrocompounds.
Aliuska Morales Helguera, M Natália D S Cordeiro, Miguel Angel Cabrera Pérez, Robert D Combes, Maykel Pérez González

Bioorg Med Chem· March 2008

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The FRAME Research Programme under the direction of Dr Richard Clothier.
Robert D Combes

Altern Lab Anim· October 2007

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