Publications by authors named "Robert D M Davies"

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Cubanes in medicinal chemistry: synthesis of functionalized building blocks.
Joanna Wlochal, Robert D M Davies, Jonathan Burton

August 2014

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Tricyclic Indazoles-A Novel Class of Selective Estrogen Receptor Degrader Antagonists.
James S Scott, Andrew Bailey, David Buttar, Rodrigo J Carbajo, Jon Curwen, Robert D M Davies

J Med Chem· February 2019

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Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin-1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88 Diffuse Large B-Cell Lymphoma.
James S Scott, Sébastien L Degorce, Rana Anjum, Janet Culshaw, Robert D M Davies, Nichola L Davies

J Med Chem· December 2017

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Tetrahydroisoquinoline Phenols: Selective Estrogen Receptor Downregulator Antagonists with Oral Bioavailability in Rat.
James S Scott, Andrew Bailey, Robert D M Davies, Sébastien L Degorce, Philip A MacFaul

ACS Med Chem Lett· January 2016

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Identification, optimization, and pharmacology of acylurea GHS-R1a inverse agonists.
William McCoull, Peter Barton, Alastair J H Brown, Suzanne S Bowker, Jennifer Cameron, Robert D M Davies

J Med Chem· July 2014

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The first intramolecular silene Diels-Alder reactions.
Michal Czyzewski, Jonathan D Sellars, Tamaz Guliashvili, Julius Tibbelin, Lisa Johnstone, Robert D M Davies

Chem Commun (Camb)· March 2014

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Design and optimization of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase 1 (DGAT1) leading to a clinical candidate dimethylpyrazinecarboxamide phenylcyclohexylacetic acid (AZD7687).
Jonas G Barlind, Udo A Bauer, Alan M Birch, Susan Birtles, Linda K Buckett, Robert D M Davies

J Med Chem· December 2012

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Formal synthesis of merrilactone A using a domino cyanide 1,4-addition-aldol cyclization.
Naim Nazef, Robert D M Davies, Michael F Greaney

Org Lett· July 2012

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Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes.
William McCoull, Matthew S Addie, Alan M Birch, Susan Birtles, Linda K Buckett, Robert D M Davies

Bioorg Med Chem Lett· June 2012

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Stereocontrolled total synthesis of (-)-callipeltoside A.
Ian Paterson, Robert D M Davies, Annekatrin C Heimann, Rodolfo Marquez, Arndt Meyer

Org Lett· November 2003

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Total Synthesis of the Callipeltoside Aglycon.
Ian Paterson, Robert D M Davies, Rodolfo Marquez

Angew Chem Int Ed Engl· February 2001

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Total Synthesis of the Callipeltoside Aglycon We thank the EPSRC (R.D.M.D; GR/N08520), Girton College, Cambridge (R.M.), and Merck for support, and Setu P. Roday (Cambridge) for kindly assisting with the molecular modeling studies.
Ian Paterson, Robert D. M. Davies, Rodolfo Marquez

Angew Chem Int Ed Engl· February 2001

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