Publications by authors named "Robert L Matts"

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Structural basis of the key residue W320 responsible for Hsp90 conformational change.
Shuxia Peng, Robert L Matts, Junpeng Deng

J Biomol Struct Dyn· November 2023

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Elucidation of novel TRAP1-Selective inhibitors that regulate mitochondrial processes.
Taylor Merfeld, Shuxia Peng, Bradley M Keegan, Vincent M Crowley, Christopher M Brackett, Robert L Matts

Eur J Med Chem· October 2023

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Crystal structure of the middle and C-terminal domains of Hsp90α labeled with a coumarin derivative reveals a potential allosteric binding site as a drug target.
Shuxia Peng, Jeff Woodruff, Prabhat Kumar Pathak, Robert L Matts, Junpeng Deng

Acta Crystallogr D Struct Biol· May 2022

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Selective Inhibition of the Hsp90α Isoform.
Sanket J Mishra, Anuj Khandelwal, Monimoy Banerjee, Maurie Balch, Shuxia Peng, Robert L Matts

Angew Chem Int Ed Engl· May 2021

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A High-Throughput Screen for Inhibitors of the Hsp90-Chaperone Machine.
Jason Davenport, Lakshmi Galam, Robert L Matts

Methods Mol Biol· July 2018

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Proteomic Profiling of Hsp90 Inhibitors.
Sudhakar Voruganti, Jake T Kline, Maurie J Balch, Janet Rogers, Robert L Matts

Methods Mol Biol· July 2018

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Identification of proteins associated with Aha1 in HeLa cells by quantitative proteomics.
Liang Sun, Steven D Hartson, Robert L Matts

Biochim Biophys Acta· May 2015

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Hsp90-dependent assembly of the DBC2/RhoBTB2-Cullin3 E3-ligase complex.
Jacob R Manjarrez, Liang Sun, Thomas Prince, Robert L Matts

PLoS One· December 2014

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High-throughput screen of natural product libraries for hsp90 inhibitors.
Jason Davenport, Maurie Balch, Lakshmi Galam, Antwan Girgis, Jessica Hall, Robert L Matts

Biology (Basel)· February 2014

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Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors.
Takrima Sadikot, Megan Swink, Jeffery D Eskew, Douglas Brown, Huiping Zhao, Robert L Matts

Assay Drug Dev Technol· October 2013

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The anticancer drug AUY922 generates a proteomics fingerprint that is highly conserved among structurally diverse Hsp90 inhibitors.
Sudhakar Voruganti, Jeff C Lacroix, Chelsea N Rogers, Janet Rogers, Robert L Matts

J Proteome Res· August 2013

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Characterization of the interaction of Aha1 with components of the Hsp90 chaperone machine and client proteins.
Liang Sun, Thomas Prince, Jacob R Manjarrez, Bradley T Scroggins, Robert L Matts

Biochim Biophys Acta· June 2012

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Approaches for defining the Hsp90-dependent proteome.
Steven D Hartson, Robert L Matts

Biochim Biophys Acta· March 2012

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Development and characterization of a novel C-terminal inhibitor of Hsp90 in androgen dependent and independent prostate cancer cells.
Jeffery D Eskew, Takrima Sadikot, Pedro Morales, Alicia Duren, Irene Dunwiddie, Robert L Matts

BMC Cancer· October 2011

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Elucidation of the Hsp90 C-terminal inhibitor binding site.
Robert L Matts, Anshuman Dixit, Laura B Peterson, Liang Sun, Sudhakar Voruganti

ACS Chem Biol· August 2011

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Identification and initial SAR of silybin: an Hsp90 inhibitor.
Huiping Zhao, Gary E Brandt, Lakshmi Galam, Robert L Matts, Brian S J Blagg

Bioorg Med Chem Lett· May 2011

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Gambogic acid, a natural product inhibitor of Hsp90.
Jason Davenport, Jacob R Manjarrez, Laura Peterson, Brian Krumm, Brian S J Blagg, Robert L Matts

J Nat Prod· May 2011

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A systematic protocol for the characterization of Hsp90 modulators.
Robert L Matts, Gary E L Brandt, Yuanming Lu, Anshuman Dixit, Mehdi Mollapour

Bioorg Med Chem· January 2011

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Assays for identification of Hsp90 inhibitors and biochemical methods for discriminating their mechanism of action.
Robert L Matts, Jacob R Manjarrez

Curr Top Med Chem· February 2010

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Characterization of a novel novobiocin analogue as a putative C-terminal inhibitor of heat shock protein 90 in prostate cancer cells.
Shawna B Matthews, George A Vielhauer, Craig A Manthe, Vamsee K Chaguturu, Kristen Szabla, Robert L Matts

Prostate· January 2010

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KU135, a novel novobiocin-derived C-terminal inhibitor of the 90-kDa heat shock protein, exerts potent antiproliferative effects in human leukemic cells.
Shary N Shelton, Mary E Shawgo, Shawna B Matthews, Yuanming Lu, Alison C Donnelly, Robert L Matts

Mol Pharmacol· December 2009

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Synthesis and evaluation of Hsp90 inhibitors that contain the 1,4-naphthoquinone scaffold.
M Kyle Hadden, Stephanie A Hill, Jason Davenport, Robert L Matts, Brian S J Blagg

Bioorg Med Chem· January 2009

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Derrubone, an inhibitor of the Hsp90 protein folding machinery.
M Kyle Hadden, Lakshmi Galam, Jason E Gestwicki, Robert L Matts, Brian S J Blagg

J Nat Prod· December 2007

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High-throughput assay for the identification of Hsp90 inhibitors based on Hsp90-dependent refolding of firefly luciferase.
Lakshmi Galam, M Kyle Hadden, Zeqiang Ma, Qi-Zhuang Ye, Bo-Geon Yun, Robert L Matts

Bioorg Med Chem· March 2007

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Direct interaction of the cell division cycle 37 homolog inhibits endothelial nitric oxide synthase activity.
M Brennan Harris, Manuela Bartoli, Sarika G Sood, Robert L Matts, Richard C Venema

Circ Res· February 2006

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