Publications by authors named "Robert Letienne"

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F 16915 prevents heart failure-induced atrial fibrillation: a promising new drug as upstream therapy.
Bruno Le Grand, Robert Letienne, Elisabeth Dupont-Passelaigue, Frédérique Lantoine-Adam, Frédéric Longo

Naunyn Schmiedebergs Arch Pharmacol· July 2014

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Protease-activated receptor-1 antagonist F 16618 reduces arterial restenosis by down-regulation of tumor necrosis factor α and matrix metalloproteinase 7 expression, migration, and proliferation of vascular smooth muscle cells.
Pauline Chieng-Yane, Arnaud Bocquet, Robert Létienne, Thierry Bourbon, Sylvie Sablayrolles

J Pharmacol Exp Ther· March 2011

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Protease-activated receptor 1 antagonists prevent platelet aggregation and adhesion without affecting thrombin time.
Florence Nadal-Wollbold, Arnaud Bocquet, Thierry Bourbon, Robert Létienne, Bruno Le Grand

Eur J Pharmacol· October 2010

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Antithrombotic activity of F 16618, a new PAR1 antagonist evaluated in extracorporeal arterio-venous shunt in the rat.
Robert Létienne, Anne Leparq-Panissié, Yannick Calmettes, Florence Nadal-Wollbold, Michel Perez

Biochem Pharmacol· June 2010

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PAR1 antagonist mediated antithrombotic activity in extracorporeal arterio-venous shunt in the rat.
Robert Létienne, Anne Leparq-Panissié, Arnaud Bocquet, Yannick Calmettes, Charlène Culié

Thromb Res· March 2010

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Myocardial protection by F 15845, a persistent sodium current blocker, in an ischemia-reperfusion model in the pig.
Robert Létienne, Lydia Bel, Anne-Marie Bessac, Bernard Vacher, Bruno Le Grand

Eur J Pharmacol· December 2009

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Discovery of novel protease activated receptors 1 antagonists with potent antithrombotic activity in vivo.
Michel Perez, Marie Lamothe, Catherine Maraval, Etienne Mirabel, Chantal Loubat, Robert Letienne

J Med Chem· October 2009

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3-(R)-[3-(2-methoxyphenylthio-2-(S)-methylpropyl]amino-3,4-dihydro-2H-1,5-benzoxathiepine bromhydrate (F 15845) prevents ischemia-induced heart remodeling by reduction of the intracellular Na+ overload.
Bruno Vié, Sylvie Sablayrolles, Robert Létienne, Bernard Vacher, Amaria Darmellah

J Pharmacol Exp Ther· September 2009

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Na+ currents in cardioprotection: better to be late.
Bruno Le Grand, Christophe Pignier, Robert Létienne, Francis Colpaert, Florence Cuisiat

J Med Chem· July 2009

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Effects of a new PAR1 antagonist, F 16618, on smooth muscle cell contraction.
Arnaud Bocquet, Robert Létienne, Sylvie Sablayrolles, Luc De Vries, Michel Perez

Eur J Pharmacol· June 2009

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Sodium late current blockers in ischemia reperfusion: is the bullet magic?
Bruno Le Grand, Christophe Pignier, Robert Létienne, Florence Cuisiat, Françoise Rolland

J Med Chem· July 2008

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Effects of SM-20550 against myocardial infarction-induced arrhythmias, late infarct expansion, and left ventricular dysfunction.
Noëlle Grosjean, Bruno Vié, Robert Létienne, Bruno Le Grand

J Cardiovasc Pharmacol· November 2007

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Cardioprotection of cariporide evaluated by plasma myoglobin and troponin I in myocardial infarction in pigs.
Robert Létienne, Lydia Bel, Anne-Marie Bessac, Delphine Denais, Anne-Dominique Degryse

Fundam Clin Pharmacol· April 2006

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Pharmacological characterisation of sodium channels in sinoatrial node pacemaking in the rat heart.
Robert Létienne, Bruno Vié, Bruno Le Grand

Eur J Pharmacol· January 2006

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Donitriptan decreases jugular venous oxygen saturation in rats in the absence of cranial vasoconstriction: an overlooked mechanism of antimigraine action?
Robert Létienne, Jean-Christophe Blanchet, Estelle Sole, Gareth W John, Bruno Le Grand

J Pharmacol Exp Ther· November 2005

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KC 12291: an atypical sodium channel blocker with myocardial antiischemic properties.
Gareth W John, Robert Létienne, Bruno Le Grand, Christophe Pignier, Bernard Vacher

Cardiovasc Drug Rev· July 2004

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Investigation of the effects of naratriptan, rizatriptan, and sumatriptan on jugular venous oxygen saturation in anesthetized pigs: implications for their mechanism of acute antimigraine action.
Robert Létienne, Yvan Verscheure, Gareth W John

J Pharmacol Exp Ther· October 2003

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Donitriptan selectively decreases jugular venous oxygen saturation in the anesthetized pig: further insights into its mechanism of action relevant to headache relief.
Robert Letienne, Yvan Verscheure, Michel Perez, Bruno Le Grand, Francis C Colpaert

J Pharmacol Exp Ther· May 2003

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