Publications by authors named "Robert Maile"

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DAMP-driven trained immunity: metabolic and epigenetic reprogramming in critical illness and chronic inflammation.
Han G Kim, Jaimar C Rincon, Philip A Efron, Robert Maile

Front Immunol· December 2025

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Prolonged Loss of Oxidative Phosphorylation and Mitochondrial Mass Characterize CD66b Leukocytes from Patients with Sepsis.
Christine Rodhouse, Evan L Barrios, Leilani Zeumer-Spataro, Leandro Balzano-Nogueira, Ruoxuan Wu, Robert Maile

bioRxiv· December 2025

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Optimization of Pre-Clinical Rodent Research Models of Human Shock: Part 1 Intra-abdominal Sepsis.
Christine Rodhouse, Zoe Michael, Alexandria Byskosh, Franccesco P Boeno, Miguel Hernandez-Rios, Robert Maile

Shock· November 2025

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Trauma-induced alterations in bone marrow exosome microRNA profiles.
Athina L Yoham, Agneta Peethala, Letitia E Bible, Kolenkode B Kannan, Casey Wheeler, Robert Maile

J Trauma Acute Care Surg· November 2025

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Macrophages Polarization as a Potential Driver and a Therapeutic Target for Sepsis-induced Cognitive Impairment in Older Adults.
Rola S Zeidan, Simon Reinhard, Shannon Sykes, Catherine Price, Shannon Wallet, Robert Maile

Shock· October 2025

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Indoleamine 2,3-dioxygenase-galectin-3 fusion protein remodels inflammatory and fibrotic programs, ameliorating imiquimod-induced psoriasis.
Jennifer A Simonovich, Sabrina L Macias, Mingqi Zhou, Marija Portelli, Isha Verma, Robert Maile

NPJ Biomed Innov· October 2025

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Chromatin Remodeling and Transcriptional Silencing Define the Dynamic Innate Immune Response of Tissue Resident Macrophages After Burn Injury.
Han G Kim, Marie-Pierre L Gauthier, Aidan Higgs, Denise A Hernandez, Mingqi Zhou, Robert Maile

Shock· October 2025

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Quantifying Nuance within Sepsis-Associated Immune Suppression toward Diagnostic Certainty.
Charles C Caldwell, Robert Maile, Monty B Mazer, Patrick W McGonagill, Christian B Bergmann

Shock· October 2025

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Age- and Sex- Driven Transcriptional and Metabolic Diversity in Myeloid-Derived Suppressor Cells After Mouse Sepsis.
Christine Rodhouse, Dayuan Wang, Hongru Tang, Valerie E Polcz, Miguel Hernández-Ríos, Robert Maile

bioRxiv· October 2025

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Sepsis Induces Age- and Sex-Specific Chromatin Remodeling in Myeloid-Derived Suppressor Cells.
Angel M Charles, Christine E Rodhouse, Dijoia B Darden, Marie-Pierre L Gauthier, Mingqi Zhou, Robert Maile

bioRxiv· October 2025

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Nitric Oxide-Releasing, Hyaluronic Acid-Coated Electrospun Fibers as Dual-Action Wound Dressings.
Margery E Purvis, Samantha L Picciotti, Anna L Lynch, Taron M Bradshaw, Darci E Anderson, Robert Maile

ACS Appl Bio Mater· September 2025

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Monocyte Anisocytosis Can Discriminate Between Sepsis and Sterile Inflammation, but not Mortality, in Critically Ill Surgical/Trauma Patients: A Secondary Prospective Analysis.
Miguel Hernández-Ríos, Ruoxuan Wu, Valerie A Polcz, Rachel D Burnside, Lael M Yonker, Robert Maile

Crit Care Explor· September 2025

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Temporal changes in the protein cargo of extracellular vesicles and resultant immune reprogramming after severe burn injury in humans and mice.
Micah L Willis, Roland F Seim, Laura E Herring, Angie L Mordant, Thomas S Webb, Robert Maile

Front Immunol· June 2025

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Chromatin Remodeling and Transcriptional Silencing Define the Dynamic Innate Immune Response of Tissue Resident Macrophages After Burn Injury.
Han G Kim, Marie-Pierre L Gauthier, Aidan Higgs, Denise A Hernandez, Mingqi Zhou, Robert Maile

bioRxiv· May 2025

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Temporal changes in the protein cargo of extracellular vesicles and resultant immune reprogramming after severe burn injury in humans and mice.
Micah L Willis, Roland Seim, Laura E Herring, Angie L Mordant, Thomas S Webb, Robert Maile

bioRxiv· March 2025

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MULTIMODAL NUCLEAR FACTOR-ERYTHROID-2-RELATED FACTOR (NRF2) THERAPY IN THE CONTEXT OF MAMMALIAN TARGET OF RAPAMYCIN (MTOR) INHIBITION REPROGRAMS THE ACUTE SYSTEMIC AND PULMONARY IMMUNE RESPONSE AFTER COMBINED BURN AND INHALATION INJURY.
Matthew D Alves, Ryan A Clark, Denise A Hernandez, Madelyn P Bucci, Duo Chen, Robert Maile

Shock· December 2024

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Unique lymphocyte transcriptomic profiles in septic patients with chronic critical illness.
Evan L Barrios, Leandro Balzano-Nogueira, Valerie E Polcz, Christine Rodhouse, Jack R Leary, Robert Maile

Front Immunol· December 2024

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Persistence and Sexual Dimorphism of Gut Dysbiosis and Pathobiome after Sepsis and Trauma.
Jennifer A Munley, Gwoncheol Park, Lauren S Kelly, Kolenkode B Kannan, Robert T Mankowski, Robert Maile

Ann Surg· September 2024

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Resolvin D2/GPR18 signaling enhances monocytic myeloid-derived suppressor cell function to mitigate abdominal aortic aneurysm formation.
Paolo Bellotti, Zachary Ladd, Victoria Leroy, Gang Su, Shiven Sharma, Robert Maile

FASEB J· September 2024

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TRANSCRIPTOMIC DIFFERENCES IN PERIPHERAL MONOCYTE POPULATIONS IN SEPTIC PATIENTS BASED ON OUTCOME.
Evan L Barrios, Jaimar C Rincon, Micah Willis, Valerie E Polcz, Jack R Leary, Robert Maile

Shock· August 2024

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Current updates in precision and personalized medicine in sepsis and trauma.
Stacey K Drury, Shannon M Wallet, Robert Maile, Philip A Efron, Alicia M Mohr

Surgery· August 2024

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Instantly adhesive and ultra-elastic patches for dynamic organ and wound repair.
Parth Chansoria, Ameya Chaudhari, Emma L Etter, Emily E Bonacquisti, Mairead K Heavey, Robert Maile

Nat Commun· June 2024

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The post-septic peripheral myeloid compartment reveals unexpected diversity in myeloid-derived suppressor cells.
Evan L Barrios, Jack R Leary, Dijoia B Darden, Jaimar C Rincon, Micah Willis, Robert Maile

Front Immunol· May 2024

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Resolvin D2/GPR18 signaling enhances monocytic myeloid-derived suppressor cell function to mitigate abdominal aortic aneurysm formation.
Paolo Bellotti, Zachary Ladd, Victoria Leroy, Gang Su, Shiven Sharma, Robert Maile

bioRxiv· February 2024

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Gut mycobiome dysbiosis after sepsis and trauma.
Gwoncheol Park, Jennifer A Munley, Lauren S Kelly, Kolenkode B Kannan, Robert T Mankowski, Robert Maile

Crit Care· January 2024

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