Publications by authors named "Robert Oldham"

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A "Function-First" Approach to Identify Regulatory T cell-Targeting Antibodies for Immunotherapy.
Kirstie L S Cleary, Monika Semmrich, Linda Martensson, Ulla-Carin Tornberg, David Ermert, Robert J Oldham

Cancer Immunol Res· December 2025

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A First-in-Class mAb (BI-1607) Targeting FcγRIIB: Preclinical Data and First-in-Human Studies in Patients with HER2-Positive Advanced Solid Tumors.
Javier Cortés, Araceli Priego, Elena Garralda, Katerin Rojas, Simon R Lord, Robert Oldham

Clin Cancer Res· December 2025

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CD40L and IL-4 suppress NK cell-mediated antibody-dependent cellular cytotoxicity through the HLA-E:NKG2A axis.
Lara V Graham, Ludmila Horehajova, Marco V Haselager, Jack G Fisher, Jamie Lee Roos, Robert J Oldham

Immunother Adv· September 2025

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FcγRIIB (CD32B) antibodies enhance immune responses through activating FcγRs.
Alexander P Simpson, Robert J Oldham, Kerry L Cox, Martin C Taylor, Sonya James

Clin Exp Immunol· January 2025

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FcγRIIB controls antibody-mediated target cell depletion by ITIM-independent mechanisms.
Alexander P Simpson, Ali Roghanian, Robert J Oldham, H T Claude Chan, Christine A Penfold

Cell Rep· July 2022

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HIF activation enhances FcγRIIb expression on mononuclear phagocytes impeding tumor targeting antibody immunotherapy.
Khiyam Hussain, Rena Liu, Rosanna C G Smith, Kri T J Müller, Mohammadmersad Ghorbani, Robert J Oldham

J Exp Clin Cancer Res· April 2022

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On-target IgG hexamerisation driven by a C-terminal IgM tail-piece fusion variant confers augmented complement activation.
Joshua M Sopp, Shirley J Peters, Tania F Rowley, Robert J Oldham, Sonya James

Commun Biol· September 2021

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Fc-Engineering for Modulated Effector Functions-Improving Antibodies for Cancer Treatment.
Rena Liu, Robert J Oldham, Emma Teal, Stephen A Beers, Mark S Cragg

Antibodies (Basel)· November 2020

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FcγRII (CD32) modulates antibody clearance in NOD SCID mice leading to impaired antibody-mediated tumor cell deletion.
Robert J Oldham, C Ian Mockridge, Sonya James, Patrick J Duriez, H T Claude Chan

J Immunother Cancer· June 2020

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The PI3Kδ-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo.
Adam Palazzo, Sylvia Herter, Laura Grosmaire, Randy Jones, Christian R Frey, Robert J Oldham

J Immunol· April 2018

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Detection of Experimental and Clinical Immune Complexes by Measuring SHIP-1 Recruitment to the Inhibitory FcγRIIB.
Richard J Stopforth, Robert J Oldham, Alison L Tutt, Patrick Duriez, H T Claude Chan

J Immunol· March 2018

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Cancer Biotherapy: More Than Immunotherapy.
Robert K Oldham

Cancer Biother Radiopharm· May 2017

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Development and Characterization of Monoclonal Antibodies Specific for Mouse and Human Fcγ Receptors.
Alison L Tutt, Sonya James, Stéphanie A Laversin, Thomas R W Tipton, Margaret Ashton-Key, Robert J Oldham

J Immunol· December 2015

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NAD⁺-Metabolizing Ectoenzymes in Remodeling Tumor-Host Interactions: The Human Myeloma Model.
Alberto L Horenstein, Antonella Chillemi, Valeria Quarona, Andrea Zito, Ilaria Roato, Robert J Oldham

Cells· September 2015

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Antagonistic human FcγRIIB (CD32B) antibodies have anti-tumor activity and overcome resistance to antibody therapy in vivo.
Ali Roghanian, Ingrid Teige, Linda Mårtensson, Kerry L Cox, Mathilda Kovacek, Robert J Oldham

Cancer Cell· April 2015

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Antigenic modulation limits the effector cell mechanisms employed by type I anti-CD20 monoclonal antibodies.
Thomas R W Tipton, Ali Roghanian, Robert J Oldham, Matthew J Carter, Kerry L Cox

Blood· March 2015

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Upregulation of FcγRIIb on monocytes is necessary to promote the superagonist activity of TGN1412.
Khiyam Hussain, Chantal E Hargreaves, Ali Roghanian, Robert J Oldham, H T Claude Chan

Blood· January 2015

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Mental health aspects of disasters.
Robert L Oldham

South Med J· January 2013

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A pharmacodynamic study of the P-glycoprotein antagonist CBT-1® in combination with paclitaxel in solid tumors.
Ronan J Kelly, Robert W Robey, Clara C Chen, Deborah Draper, Victoria Luchenko, Robert K Oldham

Oncologist· October 2012

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Commentary on "intimate partner violence education for medical students: toward a comprehensive curriculum revision".
Robert Oldham

South Med J· April 2012

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Attachment styles of Oregonians who request physician-assisted death.
Robert L Oldham, Steven K Dobscha, Elizabeth R Goy, Linda Ganzini

Palliat Support Care· June 2011

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Systematic review of prevalence, correlates, and treatment outcomes for chronic non-cancer pain in patients with comorbid substance use disorder.
Benjamin J Morasco, Susan Gritzner, Lynsey Lewis, Robert Oldham, Dennis C Turk

Pain· March 2011

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Monoclonal antibodies in cancer therapy: 25 years of progress.
Robert K Oldham, Robert O Dillman

J Clin Oncol· April 2008

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Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)).
Robert W Robey, Suneet Shukla, Elizabeth M Finley, Robert K Oldham, Daryl Barnett

Biochem Pharmacol· March 2008

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Body mass index relates to males with posttraumatic stress disorder.
W Victor R Vieweg, Antony Fernandez, Demetrios A Julius, Lynn Satterwhite, John Benesek, Robert Oldham

J Natl Med Assoc· April 2006

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