Publications by authors named "Robert Roeder"

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H4K16 acylations destabilize chromatin architecture and facilitate transcriptional response during metabolic perturbations.
Sandra Nitsch, Aria E Coraor, Tamas Schauer, Yiheng Wu, Jianfeng Sun, Robert G Roeder

Mol Cell· December 2025

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MED1 IDR deacetylation controls stress responsive genes through RNA Pol II recruitment.
Ran Lin, Yan Mo, Douglas Barrows, Wenbin Mei, Takashi Onikubo, Robert G Roeder

Nat Chem Biol· October 2025

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JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells.
Qian Chen, Saisai Wang, Juqing Zhang, Min Xie, Bin Lu, Robert G Roeder

Protein Cell· May 2025

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Resistance of estrogen receptor function to BET bromodomain inhibition is mediated by transcriptional coactivator cooperativity.
Sicong Zhang, Robert G Roeder

Nat Struct Mol Biol· January 2025

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The BAF complex enhances transcription through interaction with H3K56ac in the histone globular domain.
Kwangbeom Hyun, Jihye Ahn, Hyoungmin Kim, Jihyun Kim, Yong-In Kim, Robert G Roeder

Nat Commun· November 2024

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MLL-AF9 regulates transcriptional initiation in mixed lineage leukemic cells.
Zimei Yang, Ge Zhang, Ruoyu Zhao, Tian Tian, Junhong Zhi, Robert G Roeder

J Biol Chem· August 2024

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An IDR-dependent mechanism for nuclear receptor control of Mediator interaction with RNA polymerase II.
Haiyan Zhao, Jiaqin Li, Yufei Xiang, Sohail Malik, Supriya V Vartak, Robert G Roeder

Mol Cell· July 2024

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Resistance of estrogen receptor function to BET bromodomain inhibition is mediated by transcriptional coactivator cooperativity.
Sicong Zhang, Robert G Roeder

bioRxiv· July 2024

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TAF2, within the TFIID complex, regulates the expression of a subset of protein-coding genes.
I-Hsin Cheng, Wen-Chieh Pi, Chung-Hao Hsu, Yiran Guo, Jun-Lin Lai, Robert G Roeder

Cell Death Discov· May 2024

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Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment.
Jie Li, Christopher R Chin, Hsia-Yuan Ying, Cem Meydan, Matthew R Teater, Robert G Roeder

Nat Commun· April 2024

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MED1 IDR acetylation reorganizes the transcription preinitiation complex, rewires 3D chromatin interactions and reprograms gene expression.
Ran Lin, Douglas Barrows, Yan Mo, Takashi Onikubo, Zhiguo Zhang, Robert G Roeder

bioRxiv· March 2024

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Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.
Jie Gao, Miki Jishage, Yuzhu Wang, Rui Wang, Meng Chen, Robert G Roeder

Int J Biol Macromol· December 2023

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Regulation of the RNA polymerase II pre-initiation complex by its associated coactivators.
Sohail Malik, Robert G Roeder

Nat Rev Genet· November 2023

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SETD1A function in leukemia is mediated through interaction with mitotic regulators BuGZ/BUB3.
Sarah Perlee, Sota Kikuchi, Tomoyoshi Nakadai, Takeshi Masuda, Sumio Ohtsuki, Robert G Roeder

EMBO Rep· October 2023

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Cooperation between IRTKS and deubiquitinase OTUD4 enhances the SETDB1-mediated H3K9 trimethylation that promotes tumor metastasis via suppressing E-cadherin expression.
Xiaofang Cui, Xueying Shang, Jia Xie, Chenyi Xie, Zhanyun Tang, Robert G Roeder

Cancer Lett· October 2023

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MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.
Nicholas T Crump, Alastair L Smith, Laura Godfrey, Ana M Dopico-Fernandez, Nicholas Denny, Robert G Roeder

Nat Commun· August 2023

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Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin.
Nan Liu, Tsuyoshi Konuma, Rajal Sharma, Deyu Wang, Nan Zhao, Robert G Roeder

Mol Cell· July 2023

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SET1 and p300 Act Synergistically, through Coupled Histone Modifications, in Transcriptional Activation by p53.
Zhanyun Tang, Wei-Yi Chen, Miho Shimada, Uyen T T Nguyen, Jaehoon Kim, Robert G Roeder

Cell· May 2023

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Two target gene activation pathways for orphan ERR nuclear receptors.
Tomoyoshi Nakadai, Miho Shimada, Keiichi Ito, Murat Alper Cevher, Chi-Shuen Chu, Robert G Roeder

Cell Res· February 2023

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Cooperative super-enhancer inactivation caused by heterozygous loss of CREBBP and KMT2D skews B cell fate decisions and yields T cell-depleted lymphomas.
Jie Li, Christopher R Chin, Hsia-Yuan Ying, Cem Meydan, Matthew R Teater, Robert G Roeder

bioRxiv· February 2023

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Functional partitioning of transcriptional regulators by patterned charge blocks.
Heankel Lyons, Reshma T Veettil, Prashant Pradhan, Christy Fornero, Nancy De La Cruz, Robert G Roeder

Cell· January 2023

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Correction for Malik et al., "Structural and Functional Organization of TRAP220, the TRAP/Mediator Subunit That Is Targeted by Nuclear Receptors".
Sohail Malik, Mohamed Guermah, Chao-Xing Yuan, Weizhen Wu, Soichiro Yamamura, Robert G Roeder

Mol Cell Biol· November 2022

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Structural basis of human SNAPc recognizing proximal sequence element of snRNA promoter.
Jianfeng Sun, Xue Li, Xuben Hou, Sujian Cao, Wenjin Cao, Robert G Roeder

Nat Commun· November 2022

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LYL1 facilitates AETFC assembly and gene activation by recruiting CARM1 in t(8;21) AML.
Qian Chen, Murat A Cevher, Qi Jiang, Saisai Wang, Xiaojian Sun, Robert G Roeder

Proc Natl Acad Sci U S A· October 2022

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A direct comparison between AML1-ETO and ETO2-GLIS2 leukemia fusion proteins reveals context-dependent binding and regulation of target genes and opposite functions in cell differentiation.
Yi-Fan Zhang, Xiao-Lin Wang, Chun-Hui Xu, Na Liu, Ling Zhang, Robert G Roeder

Front Cell Dev Biol· September 2022

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