Publications by authors named "Robert Root-Bernstein"

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Capsaicin (But Not Other Vanillins) Enhances Estrogen Binding to Its Receptor: Implications for Power Sports and Cancers.
Maja Pietrowicz, Robert Root-Bernstein

Life (Basel)· January 2025

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'Evolutionary poker': an agent-based model of interactome emergence and epistasis tested against Lenski's long-term E. coli experiments.
Robert S Root-Bernstein, Morton I Bernstein

J Physiol· June 2024

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Integrate chaos theory with Epoker and leave God out of it!
Robert Root-Bernstein

J Physiol· June 2024

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T-Cell Receptor Sequences Identify Combined Coxsackievirus- Infections as Triggers for Autoimmune Myocarditis and Coxsackievirus- Infections for Type 1 Diabetes.
Robert Root-Bernstein

Int J Mol Sci· February 2024

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SARS-CoV-2 and Its Bacterial Co- or Super-Infections Synergize to Trigger COVID-19 Autoimmune Cardiopathies.
Robert Root-Bernstein, Jack Huber, Alison Ziehl, Maja Pietrowicz

Int J Mol Sci· July 2023

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Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection.
Sunil K Ahuja, Muthu Saravanan Manoharan, Grace C Lee, Lyle R McKinnon, Justin A Meunier, Robert Root-Bernstein

Nat Commun· June 2023

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and Enteroviruses as Synergistic Triggers of Type 1 Diabetes Mellitus.
Robert Root-Bernstein, Kaylie Chiles, Jack Huber, Alison Ziehl, Miah Turke

Int J Mol Sci· May 2023

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From Co-Infections to Autoimmune Disease via Hyperactivated Innate Immunity: COVID-19 Autoimmune Coagulopathies, Autoimmune Myocarditis and Multisystem Inflammatory Syndrome in Children.
Robert Root-Bernstein

Int J Mol Sci· February 2023

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T Cell Receptor Sequences Amplified during Severe COVID-19 and Multisystem Inflammatory Syndrome in Children Mimic SARS-CoV-2, Its Bacterial Co-Infections and Host Autoantigens.
Robert Root-Bernstein, Elizabeth Churchill, Shelby Oliverio

Int J Mol Sci· January 2023

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"Sea Water" Supplemented with Calcium Phosphate and Magnesium Sulfate in a Long-Term Miller-Type Experiment Yields Sugars, Nucleic Acids Bases, Nucleosides, Lipids, Amino Acids, and Oligopeptides.
Robert Root-Bernstein, Andrew G Baker, Tyler Rhinesmith, Miah Turke, Jack Huber

Life (Basel)· January 2023

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Complementary Sets of Autoantibodies Induced by SARS-CoV-2, Adenovirus and Bacterial Antigens Cross-React with Human Blood Protein Antigens in COVID-19 Coagulopathies.
Robert Root-Bernstein, Jack Huber, Alison Ziehl

Int J Mol Sci· September 2022

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Novel Apparatuses for Incorporating Natural Selection Processes into Origins-of-Life Experiments to Produce Adaptively Evolving Chemical Ecosystems.
Robert Root-Bernstein, Adam W Brown

Life (Basel)· September 2022

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Biased, Bitopic, Opioid-Adrenergic Tethered Compounds May Improve Specificity, Lower Dosage and Enhance Agonist or Antagonist Function with Reduced Risk of Tolerance and Addiction.
Robert Root-Bernstein

Pharmaceuticals (Basel)· February 2022

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COVID-19 coagulopathies: Human blood proteins mimic SARS-CoV-2 virus, vaccine proteins and bacterial co-infections inducing autoimmunity: Combinations of bacteria and SARS-CoV-2 synergize to induce autoantibodies targeting cardiolipin, cardiolipin-binding proteins, platelet factor 4, prothrombin, and coagulation factors.
Robert Root-Bernstein

Bioessays· December 2021

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Co-Evolution of Opioid and Adrenergic Ligands and Receptors: Shared, Complementary Modules Explain Evolution of Functional Interactions and Suggest Novel Engineering Possibilities.
Robert Root-Bernstein, Beth Churchill

Life (Basel)· November 2021

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Pneumococcal and Influenza Vaccination Rates and Pneumococcal Invasive Disease Rates Set Geographical and Ethnic Population Susceptibility to Serious COVID-19 Cases and Deaths.
Robert Root-Bernstein

Vaccines (Basel)· May 2021

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Innate Receptor Activation Patterns Involving TLR and NLR Synergisms in COVID-19, ALI/ARDS and Sepsis Cytokine Storms: A Review and Model Making Novel Predictions and Therapeutic Suggestions.
Robert Root-Bernstein

Int J Mol Sci· February 2021

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Age and Location in Severity of COVID-19 Pathology: Do Lactoferrin and Pneumococcal Vaccination Explain Low Infant Mortality and Regional Differences?
Robert Root-Bernstein

Bioessays· November 2020

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Possible Cross-Reactivity between SARS-CoV-2 Proteins, CRM197 and Proteins in Pneumococcal Vaccines May Protect Against Symptomatic SARS-CoV-2 Disease and Death.
Robert Root-Bernstein

Vaccines (Basel)· September 2020

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Glutathione and Glutathione-Like Sequences of Opioid and Aminergic Receptors Bind Ascorbic Acid, Adrenergic and Opioid Drugs Mediating Antioxidant Function: Relevance for Anesthesia and Abuse.
Robert Root-Bernstein, Beth Churchill, Miah Turke

Int J Mol Sci· August 2020

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Synergistic Activation of Toll-Like and NOD Receptors by Complementary Antigens as Facilitators of Autoimmune Disease: Review, Model and Novel Predictions.
Robert Root-Bernstein

Int J Mol Sci· June 2020

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Mutual Enhancement of Opioid and Adrenergic Receptors by Combinations of Opioids and Adrenergic Ligands Is Reflected in Molecular Complementarity of Ligands: Drug Development Possibilities.
Robert Root-Bernstein, Beth Churchill, Miah Turke, Udaya K Tiruttani Subhramanyam, Joerg Labahn

Int J Mol Sci· August 2019

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The Ribosome as a Missing Link in Prebiotic Evolution III: Over-Representation of tRNA- and rRNA-Like Sequences and Plieofunctionality of Ribosome-Related Molecules Argues for the Evolution of Primitive Genomes from Ribosomal RNA Modules.
Robert Root-Bernstein, Meredith Root-Bernstein

Int J Mol Sci· January 2019

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Adrenergic Agonists Bind to Adrenergic-Receptor-Like Regions of the Mu Opioid Receptor, Enhancing Morphine and Methionine-Enkephalin Binding: A New Approach to "Biased Opioids"?
Robert Root-Bernstein, Miah Turke, Udaya K Tiruttani Subhramanyam, Beth Churchill, Joerg Labahn

Int J Mol Sci· January 2018

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Rapid Non-Enzymatic Glycation of the Insulin Receptor under Hyperglycemic Conditions Inhibits Insulin Binding In Vitro: Implications for Insulin Resistance.
Tyler Rhinesmith, Thomas Turkette, Robert Root-Bernstein

Int J Mol Sci· December 2017

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