Publications by authors named "Robert Speth"

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Paradoxical sex differences in a hamster model of angiotensin II-dependent hypertension and associated renal injury.
Hong Ji, Laura German do Nascimento, Jungeun Ahn, Dong Hyang Kwon, Gabrielle Williams, Robert C Speth

Biol Sex Differ· November 2025

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Cerebral amyloid angiopathy: a narrative review.
Natalia Motzko Noto, Robert C Speth, Lisa S Robison

Front Aging Neurosci· October 2025

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Epigenetic regulation by ketone bodies in cardiac diseases and repair.
Narasimman Gurusamy, Bandar Muteb H Almalki, Sai Katragadda, James Murray, Robert C Speth

Can J Physiol Pharmacol· August 2025

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Assessment of the therapeutic potential of salubrinal for ME/CFS and long-COVID.
Aseel Warrayat, Ayah Ali, Joulin Waked, Darcy Tocci, Robert C Speth

Trends Mol Med· May 2025

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Concerns About Data and Analyses Used in Assessing Fluoride Exposure and Children's IQ Scores.
Robert C Speth

JAMA Pediatr· May 2025

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Chronic Treatment of a Mouse Model of Cerebral Amyloid Angiopathy and Brain AT Receptor Expression.
Natalia Motzko Noto, Lisa S Robison, Robert C Speth

bioRxiv· May 2025

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N-Branched Tricyclic Guanidines as Novel Melanocortin-3 Receptor Agonists and Melanocortin-4 Receptor Antagonists.
Nicholas A Weirath, Jonathan W P Zajac, Haley M Donow, Travis M Lavoi, Clemencia Pinilla, Robert Speth

J Med Chem· February 2025

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Is chymase 1 a therapeutic target in cardiovascular disease?
Carlos M Ferrario, Sarfaraz Ahmad, Robert Speth, Louis J Dell'Italia

Expert Opin Ther Targets· November 2023

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Nanoparticle approaches for the renin-angiotensin system.
Sajini D Hettiarachchi, Young M Kwon, Yadollah Omidi, Robert C Speth

Heliyon· June 2023

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Hippocampal versus cortical deletion of cholinergic receptor muscarinic 1 in mice differentially affects post-translational modifications and supramolecular assembly of respiratory chain-associated proteins, mitochondrial ultrastructure, and respiration: implications in Alzheimer's disease.
Mohammad Golam Sabbir, Mamiko Swanson, Robert C Speth, Benedict C Albensi

Front Cell Dev Biol· May 2023

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Renin-Angiotensin System Inhibition in Advanced CKD.
Robert C Speth

N Engl J Med· April 2023

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Comparative evaluation of biased agonists Sarcosine , d-Alanine -Angiotensin (Ang) II (SD Ang II) and Sarcosine , Isoleucine -Ang II (SI Ang II) and their radioiodinated congeners binding to rat liver membrane AT receptors.
Natalia M Noto, Yazmin M Restrepo, Hong W Pang, Filipe Stoyell-Conti, Crystal A West, Robert C Speth

Pharmacol Res Perspect· February 2023

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Loss of Cholinergic Receptor Muscarinic 1 (CHRM1) Protein in the Hippocampus and Temporal Cortex of a Subset of Individuals with Alzheimer's Disease, Parkinson's Disease, or Frontotemporal Dementia: Implications for Patient Survival.
Mohammad Golam Sabbir, Robert C Speth, Benedict C Albensi

J Alzheimers Dis· November 2022

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CGP42112: the full AT2 receptor agonist and its role in the renin-angiotensin-aldosterone system: no longer misunderstood.
Yazmin M Restrepo, Natalia M Noto, Robert C Speth

Clin Sci (Lond)· November 2022

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Educational initiative in an NCATS TL1 training program to address the impact of systemic racism on human health, biomedical research, and the translational scientist.
Martha D Gay, Kimberly A Bell, Emily A Bujold, Marilla Geraci, Dexter L Lee, Robert C Speth

J Clin Transl Sci· November 2022

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Why Angiotensin II is a Poor Choice for Circulatory Support of Ventilated COVID-19 Patients Compared to Vasopressin.
Robert C Speth, Michael Bader

Med Res Arch· September 2022

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An opinion on the impacts of COVID-19 worldwide.
Robert C Speth

Bioimpacts· May 2022

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Alterations in Gene Expression of Renin-Angiotensin System Components and Related Proteins in Colorectal Cancer.
Danial Mehranfard, Gabriela Perez, Andres Rodriguez, Julia M Ladna, Christopher T Neagra, Robert C Speth

J Renin Angiotensin Aldosterone Syst· January 2022

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Cholinergic anti-inflammatory pathway and COVID-19.
Danial Mehranfard, Robert C Speth

Bioimpacts· January 2022

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Countering the classical renin-angiotensin system.
Natalia M Noto, Yazmin M Restrepo, Robert C Speth

Clin Sci (Lond)· December 2021

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Preliminary study of ovariectomy and chronic losartan-induced alterations in brain AT receptors.
Danial Mehranfard, Andrea Linares, Alesa Chabbra, Glenda Campos, Aline M A de Souza, Robert C Speth

Brain Res· September 2021

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Modulation of the rat angiotensin type 1a receptor by an upstream short open reading frame.
Parnika S Kadam, Susette C Mueller, Hong Ji, Jun Liu, Amrita V Pai, Robert C Speth

Peptides· June 2021

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Male bias in ACE2 basic science research: missed opportunity for discovery in the time of COVID-19.
Branka Miličić Stanić, Sydney Maddox, Aline M A de Souza, Xie Wu, Danial Mehranfard, Robert C Speth

Am J Physiol Regul Integr Comp Physiol· June 2021

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Chronic administration of pharmacological doses of angiotensin 1-7 and iodoangiotensin 1-7 has minimal effects on blood pressure, heart rate, and cognitive function of spontaneously hypertensive rats.
Filipe F Stoyell-Conti, Alesa Chabbra, Joseph Puthentharayil, Katya Rigatto, Robert C Speth

Physiol Rep· April 2021

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Discovery of Molecular Interactions of the Human Melanocortin-4 Receptor (hMC4R) Asp189 (D189) Amino Acid with the Endogenous G-Protein-Coupled Receptor (GPCR) Antagonist Agouti-Related Protein (AGRP) Provides Insights to AGRP's Inverse Agonist Pharmacology at the hMC4R.
Mark D Ericson, Erica M Haslach, Sathya M Schnell, Katie T Freeman, Zhimin M Xiang, Robert Speth

ACS Chem Neurosci· February 2021

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