Publications by authors named "Robert W Simms"

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Combining Pirfenidone With Mycophenolate Mofetil for Systemic Sclerosis-Related Interstitial Lung Disease (Scleroderma Lung Study III): An Investigator-Initiated, Multicenter, Randomized, Double-Blind, Placebo-Controlled Phase 2 Trial.
Dinesh Khanna, Cathie Spino, Donald P Tashkin, Elana J Bernstein, Jonathan Goldin, Robert W Simms

ACR Open Rheumatol· December 2025

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Geographic Clustering of Systemic Sclerosis in Areas of Environmental Pollution.
Noelle N Kosarek, Megan E Romano, Erika L Moen, Robert W Simms, Ashleigh Erickson

Arthritis Care Res (Hoboken)· July 2025

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Autologous Nonmyeloablative Hematopoietic Stem Cell Transplantation for Diffuse Cutaneous Systemic Sclerosis: Identifying Disease Risk Factors for Toxicity and Long-Term Outcomes in a Prospective, Single-Arm Trial.
George E Georges, Dinesh Khanna, Mark H Wener, Matthew G Mei, Maureen D Mayes, Robert W Simms

Arthritis Rheumatol· May 2025

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Efficacy and Safety of Lenabasum, a Cannabinoid Type 2 Receptor Agonist, in a Phase 3 Randomized Trial in Diffuse Cutaneous Systemic Sclerosis.
Robert Spiera, Masataka Kuwana, Dinesh Khanna, Laura Hummers, Tracy M Frech, Robert W Simms

Arthritis Rheumatol· September 2023

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Correction: Serum biomarker for diagnostic evaluation of pulmonary arterial hypertension in systemic sclerosis.
Lisa M Rice, Julio C Mantero, Eric A Stratton, Rod Warburton, Kari Roberts, Robert W Simms

Arthritis Res Ther· May 2022

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Geographic disparity in systemic sclerosis mortality in the United States: 1999-2017.
Alicia Rodriguez-Pla, Robert W Simms

J Scleroderma Relat Disord· June 2021

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Safety and efficacy of abatacept in early diffuse cutaneous systemic sclerosis (ASSET): open-label extension of a phase 2, double-blind randomised trial.
Lorinda Chung, Cathie Spino, Richard McLain, Sindhu R Johnson, Christopher P Denton, Robert W Simms

Lancet Rheumatol· December 2020

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Expert Perspectives On Clinical Challenges: Expert Perspectives: Challenges in Scleroderma.
Robert W Simms

Arthritis Rheumatol· September 2020

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Abatacept in Early Diffuse Cutaneous Systemic Sclerosis: Results of a Phase II Investigator-Initiated, Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial.
Dinesh Khanna, Cathie Spino, Sindhu Johnson, Lorinda Chung, Michael L Whitfield, Robert W Simms

Arthritis Rheumatol· January 2020

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Genetic determinants of risk in pulmonary arterial hypertension: international genome-wide association studies and meta-analysis.
Christopher J Rhodes, Ken Batai, Marta Bleda, Matthias Haimel, Laura Southgate, Robert W Simms

Lancet Respir Med· March 2019

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Microbiome dysbiosis is associated with disease duration and increased inflammatory gene expression in systemic sclerosis skin.
Michael E Johnson, Jennifer M Franks, Guoshuai Cai, Bhaven K Mehta, Tammara A Wood, Robert W Simms

Arthritis Res Ther· February 2019

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Randomised, double-blind, placebo-controlled trial of IL1-trap, rilonacept, in systemic sclerosis. A phase I/II biomarker trial.
Julio C Mantero, Nina Kishore, Jessica Ziemek, Giuseppina Stifano, Christopher Zammitti, Robert W Simms

Clin Exp Rheumatol· January 2019

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Serum biomarker for diagnostic evaluation of pulmonary arterial hypertension in systemic sclerosis.
Lisa M Rice, Julio C Mantero, Eric A Stratton, Rod Warburton, Kari Roberts, Robert W Simms

Arthritis Res Ther· August 2018

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Antisense Long Non-Coding RNAs Are Deregulated in Skin Tissue of Patients with Systemic Sclerosis.
Tobias C Messemaker, Loubna Chadli, Guoshuai Cai, Varshna S Goelela, Maaike Boonstra, Robert W Simms

J Invest Dermatol· April 2018

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Increased Expression and Modulated Regulatory Activity of Coinhibitory Receptors PD-1, TIGIT, and TIM-3 in Lymphocytes From Patients With Systemic Sclerosis.
Michelle Fleury, Anna C Belkina, Elizabeth A Proctor, Christopher Zammitti, Robert W Simms

Arthritis Rheumatol· April 2018

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Gene-level association analysis of systemic sclerosis: A comparison of African-Americans and White populations.
Olga Y Gorlova, Yafang Li, Ivan Gorlov, Jun Ying, Wei V Chen, Robert W Simms

PLoS One· February 2018

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Myeloablative Autologous Stem-Cell Transplantation for Severe Scleroderma.
Keith M Sullivan, Ellen A Goldmuntz, Lynette Keyes-Elstein, Peter A McSweeney, Ashley Pinckney, Robert W Simms

N Engl J Med· January 2018

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Inhibition of β-Catenin Signaling in the Skin Rescues Cutaneous Adipogenesis in Systemic Sclerosis: A Randomized, Double-Blind, Placebo-Controlled Trial of C-82.
Robert Lafyatis, Julio C Mantero, Jessica Gordon, Nina Kishore, Mary Carns, Robert W Simms

J Invest Dermatol· December 2017

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Development and validation of a patient-reported outcome instrument for skin involvement in patients with systemic sclerosis.
Ada Man, Jeannette K Correa, Jessica Ziemek, Robert W Simms, David T Felson

Ann Rheum Dis· August 2017

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A Proteome-Derived Longitudinal Pharmacodynamic Biomarker for Diffuse Systemic Sclerosis Skin.
Lisa M Rice, Julio C Mantero, Giuseppina Stifano, Jessica Ziemek, Robert W Simms

J Invest Dermatol· January 2017

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miR-155 in the progression of lung fibrosis in systemic sclerosis.
Romy B Christmann, Alicia Wooten, Percival Sampaio-Barros, Claudia L Borges, Carlos R R Carvalho, Robert W Simms

Arthritis Res Ther· July 2016

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The relationship between skin symptoms and the scleroderma modification of the health assessment questionnaire, the modified Rodnan skin score, and skin pathology in patients with systemic sclerosis.
Jessica Ziemek, Ada Man, Monique Hinchcliff, John Varga, Robert W Simms

Rheumatology (Oxford)· May 2016

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The American College of Rheumatology Provisional Composite Response Index for Clinical Trials in Early Diffuse Cutaneous Systemic Sclerosis.
Dinesh Khanna, Veronica J Berrocal, Edward H Giannini, James R Seibold, Peter A Merkel, Robert W Simms

Arthritis Care Res (Hoboken)· February 2016

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The American College of Rheumatology Provisional Composite Response Index for Clinical Trials in Early Diffuse Cutaneous Systemic Sclerosis.
Dinesh Khanna, Veronica J Berrocal, Edward H Giannini, James R Seibold, Peter A Merkel, Robert W Simms

Arthritis Rheumatol· February 2016

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Genetic susceptibility loci of idiopathic interstitial pneumonia do not represent risk for systemic sclerosis: a case control study in Caucasian patients.
Minghua Wu, Shervin Assassi, Gloria A Salazar, Claudia Pedroza, Olga Y Gorlova, Robert W Simms

Arthritis Res Ther· January 2016

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