Publications by authors named "Roberto Tinoco"

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The protein phosphatase 6 subunit SAPS3 modulates lifespan by regulating metabolism.
Ying Yang, Da Eun Kang, Qi Fan, Eric A Hanse, Hosung Bae, Roberto Tinoco

Sci Adv· October 2025

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Toll-like Receptor 4 Contributes to PCOS-like Metabolic and Reproductive Pathogenesis.
Kiara Wiggins, Zena Del Mundo, Julio Ayala Angulo, Nandini Naidu, Angelina Saba, Roberto Tinoco

bioRxiv· October 2025

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Spatial and Single-Cell Transcriptomics Reveal Keratinocytes as Key Players in Vulvar Lichen Sclerosus Pathogenesis.
Peng Sun, Christina N Kraus, Wei Zhao, Jiahui Xu, Susie Suh, Roberto Tinoco

J Invest Dermatol· August 2025

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Contrasting roles of PSGL-1 and PD-1 in regulating T-cell exhaustion and function during chronic viral infection.
Karla M Viramontes, Melissa N Thone, Jamie-Jean De La Torre, Emily N Neubert, Julia M DeRogatis, Roberto Tinoco

J Virol· March 2025

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UHRF1 is critical for tumor-promoting inflammation and tumorigenesis in retinoblastoma.
Yijun Gu, Marina Suarez-Pizarro, Claire C Chen, Jie Wu, Loredana Zocchi, Roberto Tinoco

bioRxiv· March 2025

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Prion protein modulation of virus-specific T cell differentiation and function during acute viral infection.
Karla M Viramontes, Melissa N Thone, Julia M DeRogatis, Emily N Neubert, Monique L Henriquez, Roberto Tinoco

Immunohorizons· January 2025

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Single-cell and spatial transcriptomics of vulvar lichen sclerosus reveal multi-compartmental alterations in gene expression and signaling cross-talk.
Peng Sun, Christina N Kraus, Wei Zhao, Jiahui Xu, Susie Suh, Roberto Tinoco

bioRxiv· August 2024

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HMGB2 regulates the differentiation and stemness of exhausted CD8 T cells during chronic viral infection and cancer.
Emily N Neubert, Julia M DeRogatis, Sloan A Lewis, Karla M Viramontes, Pedro Ortega, Roberto Tinoco

Nat Commun· September 2023

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PSGL-1 attenuates early TCR signaling to suppress CD8 T cell progenitor differentiation and elicit terminal CD8 T cell exhaustion.
Jennifer L Hope, Dennis C Otero, Eun-Ah Bae, Christopher J Stairiker, Ashley B Palete, Roberto Tinoco

Cell Rep· May 2023

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Cell-Intrinsic CD38 Expression Sustains Exhausted CD8 T Cells by Regulating Their Survival and Metabolism during Chronic Viral Infection.
Julia M DeRogatis, Emily N Neubert, Karla M Viramontes, Monique L Henriquez, Dequina A Nicholas, Roberto Tinoco

J Virol· April 2023

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PD-1 Immune Checkpoint Blockade and PSGL-1 Inhibition Synergize to Reinvigorate Exhausted T Cells.
Karla M Viramontes, Emily N Neubert, Julia M DeRogatis, Roberto Tinoco

Front Immunol· July 2022

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The cure from within? a review of the microbiome and diet in melanoma.
Priyanka Kumar, Danielle Brazel, Julia DeRogatis, Jennifer B Goldstein Valerin, Katrine Whiteson, Roberto Tinoco

Cancer Metastasis Rev· June 2022

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Targeting the PSGL-1 Immune Checkpoint Promotes Immunity to PD-1-Resistant Melanoma.
Julia M DeRogatis, Karla M Viramontes, Emily N Neubert, Monique L Henriquez, Christian F Guerrero-Juarez, Roberto Tinoco

Cancer Immunol Res· May 2022

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PSGL-1 Is a T Cell Intrinsic Inhibitor That Regulates Effector and Memory Differentiation and Responses During Viral Infection.
Roberto Tinoco, Emily N Neubert, Christopher J Stairiker, Monique L Henriquez, Linda M Bradley

Front Immunol· October 2021

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PSGL-1 Immune Checkpoint Inhibition for CD4 T Cell Cancer Immunotherapy.
Julia M DeRogatis, Karla M Viramontes, Emily N Neubert, Roberto Tinoco

Front Immunol· September 2021

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Prebiotic-Induced Anti-tumor Immunity Attenuates Tumor Growth.
Yan Li, Lisa Elmén, Igor Segota, Yibo Xian, Roberto Tinoco

Cell Rep· February 2020

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Siah2 control of T-regulatory cells limits anti-tumor immunity.
Marzia Scortegagna, Kathryn Hockemeyer, Igor Dolgalev, Joanna Poźniak, Florian Rambow, Roberto Tinoco

Nat Commun· January 2020

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Ubiquitin Ligases in Cancer Immunotherapy - Balancing Antitumor and Autoimmunity.
Yu Fujita, Roberto Tinoco, Yan Li, Daniela Senft, Ze'ev A Ronai

Trends Mol Med· May 2019

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Gut microbiota dependent anti-tumor immunity restricts melanoma growth in Rnf5 mice.
Yan Li, Roberto Tinoco, Lisa Elmén, Igor Segota, Yibo Xian

Nat Commun· April 2019

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Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis.
Yu Fujita, Ali Khateb, Yan Li, Roberto Tinoco, Tongwu Zhang

Cell Rep· September 2018

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Nuclear pore complex-mediated modulation of TCR signaling is required for naïve CD4 T cell homeostasis.
Joana Borlido, Stephen Sakuma, Marcela Raices, Florent Carrette, Roberto Tinoco

Nat Immunol· June 2018

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Fucosyltransferase Induction during Influenza Virus Infection Is Required for the Generation of Functional Memory CD4 T Cells.
Roberto Tinoco, Florent Carrette, Monique L Henriquez, Yu Fujita, Linda M Bradley

J Immunol· April 2018

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Targeting the PSGL-1 pathway for immune modulation.
Roberto Tinoco, Linda M Bradley

Immunotherapy· September 2017

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PSGL-1: A New Player in the Immune Checkpoint Landscape.
Roberto Tinoco, Dennis C Otero, Amy A Takahashi, Linda M Bradley

Trends Immunol· May 2017

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PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion.
Roberto Tinoco, Florent Carrette, Monique L Barraza, Dennis C Otero, Jonathan Magaña

Immunity· June 2016

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