Publications by authors named "Robin B Chan"

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Machine learning identifies a 5-serum cytokine panel for the early detection of chronic atrophy gastritis patients.
Fangmei An, Yan Ge, Wei Ye, Lin Ji, Ke Chen, Robin Barry Chan

Cancer Biomark· September 2024

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GV-971 attenuates α-Synuclein aggregation and related pathology.
Zhenwei Yu, Ying Yang, Robin Barry Chan, Min Shi, Tessandra Stewart

CNS Neurosci Ther· February 2024

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Utilizing machine learning and lipidomics to distinguish primary lateral sclerosis from amyotrophic lateral sclerosis.
Ikjae Lee, Jeanette A Stingone, Robin Barry Chan, Hiroshi Mitsumoto

Muscle Nerve· April 2023

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Lysosomal phospholipase A2 contributes to the biosynthesis of the atypical late endosome lipid bis(monoacylglycero)phosphate.
Jacinda Chen, Amaury Cazenave-Gassiot, Yimeng Xu, Paola Piroli, Robert Hwang, Robin Barry Chan

Commun Biol· February 2023

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Effects of APOE4 allelic dosage on lipidomic signatures in the entorhinal cortex of aged mice.
André Miguel Miranda, Archana Ashok, Robin Barry Chan, Bowen Zhou, Yimeng Xu

Transl Psychiatry· March 2022

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Astrocytic VEGFA: An essential mediator in blood-brain-barrier disruption in Parkinson's disease.
Guoyu Lan, Pan Wang, Robin Barry Chan, Zongran Liu, Zhenwei Yu

Glia· February 2022

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α-Synuclein-containing erythrocytic extracellular vesicles: essential contributors to hyperactivation of monocytes in Parkinson's disease.
Zongran Liu, Robin Barry Chan, Zhijian Cai, Xiaodan Liu, Yufeng Wu

J Neuroinflammation· February 2022

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Stable reduction of STARD4 alters cholesterol regulation and lipid homeostasis.
David B Iaea, Zachary R Spahr, Rajesh K Singh, Robin B Chan, Bowen Zhou

Biochim Biophys Acta Mol Cell Biol Lipids· April 2020

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Phospholipase D1 Ablation Disrupts Mouse Longitudinal Hippocampal Axis Organization and Functioning.
Luísa Santa-Marinha, Isabel Castanho, Rita Ribeiro Silva, Francisca Vaz Bravo, André Miguel Miranda, Robin Barry Chan

Cell Rep· March 2020

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Differential lipid composition and regulation along the hippocampal longitudinal axis.
André Miguel Miranda, Francisca Vaz Bravo, Robin B Chan, Nuno Sousa, Gilbert Di Paolo

Transl Psychiatry· April 2019

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Endoplasmic reticulum-plasma membrane contact sites integrate sterol and phospholipid regulation.
Evan Quon, Yves Y Sere, Neha Chauhan, Jesper Johansen, David P Sullivan, Robin B Chan

PLoS Biol· May 2018

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Phospholipase D functional ablation has a protective effect in an Alzheimer's disease Caenorhabditis elegans model.
Francisca Vaz Bravo, Jorge Da Silva, Robin Barry Chan, Gilbert Di Paolo, Andreia Teixeira-Castro

Sci Rep· February 2018

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Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures.
André M Miranda, Zofia M Lasiecka, Yimeng Xu, Jessi Neufeld, Sanjid Shahriar, Robin B Chan

Nat Commun· January 2018

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Metabolic activity induces membrane phase separation in endoplasmic reticulum.
Yihui Shen, Zhilun Zhao, Luyuan Zhang, Lingyan Shi, Sanjid Shahriar, Robin B Chan

Proc Natl Acad Sci U S A· December 2017

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Serum lipid alterations in GBA-associated Parkinson's disease.
Leonor Correia Guedes, Robin Barry Chan, Marcos António Gomes, Vasco A Conceição, Raquel Bouça Machado

Parkinsonism Relat Disord· November 2017

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Increased localization of APP-C99 in mitochondria-associated ER membranes causes mitochondrial dysfunction in Alzheimer disease.
Marta Pera, Delfina Larrea, Cristina Guardia-Laguarta, Jorge Montesinos, Kevin R Velasco, Robin B Chan

EMBO J· November 2017

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Elevated GM3 plasma concentration in idiopathic Parkinson's disease: A lipidomic analysis.
Robin B Chan, Adler J Perotte, Bowen Zhou, Christopher Liong, Evan J Shorr

PLoS One· August 2017

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ablation prevents Western diet-induced weight gain and hepatic steatosis because of impaired fat absorption.
Enrico Bertaggia, Kristian K Jensen, Jose Castro-Perez, Yimeng Xu, Gilbert Di Paolo, Robin B Chan

Am J Physiol Endocrinol Metab· August 2017

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HS1BP3 negatively regulates autophagy by modulation of phosphatidic acid levels.
Petter Holland, Helene Knævelsrud, Kristiane Søreng, Benan J Mathai, Alf Håkon Lystad, Robin B Chan

Nat Commun· December 2016

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Remodeling of the postsynaptic plasma membrane during neural development.
Karolina Tulodziecka, Barbara B Diaz-Rohrer, Madeline M Farley, Robin B Chan, Gilbert Di Paolo

Mol Biol Cell· November 2016

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Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis.
Donna M Conlon, Tiffany Thomas, Tatyana Fedotova, Antonio Hernandez-Ono, Gilbert Di Paolo, Robin B Chan

J Clin Invest· October 2016

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TTC39B deficiency stabilizes LXR reducing both atherosclerosis and steatohepatitis.
Joanne Hsieh, Masahiro Koseki, Matthew M Molusky, Emi Yakushiji, Ikuyo Ichi, Robin B Chan

Nature· July 2016

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Arf6 controls retromer traffic and intracellular cholesterol distribution via a phosphoinositide-based mechanism.
Catherine Marquer, Huasong Tian, Julie Yi, Jayson Bastien, Claudia Dall'Armi, Robin Barry Chan

Nat Commun· June 2016

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Behavioural traits propagate across generations via segregated iterative-somatic and gametic epigenetic mechanisms.
Emma Mitchell, Shifra L Klein, Kimon V Argyropoulos, Ali Sharma, Robin B Chan

Nat Commun· May 2016

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Role for Lipid Droplet Biogenesis and Microlipophagy in Adaptation to Lipid Imbalance in Yeast.
Jason D Vevea, Enrique J Garcia, Robin B Chan, Bowen Zhou, Mei Schultz

Dev Cell· December 2015

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