Publications by authors named "Robin Offord"

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Establishing a service to tackle problematic polypharmacy.
Frances Bennett, Neha Shah, Robin Offord, Robin Ferner, Reecha Sofat

Future Healthc J· October 2020

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Development and pharmacokinetics of a combination vaginal ring for sustained release of dapivirine and the protein microbicide 5P12-RANTES.
John W McBride, R Karl Malcolm, Nicola Dias, David Cameron, Robin E Offord

Int J Pharm· June 2019

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Vaginal rings with exposed cores for sustained delivery of the HIV CCR5 inhibitor 5P12-RANTES.
John W McBride, Peter Boyd, Nicola Dias, David Cameron, Robin E Offord

J Control Release· March 2019

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Pharmacokinetics of the Protein Microbicide 5P12-RANTES in Sheep following Single-Dose Vaginal Gel Administration.
John W McBride, Nicola Dias, David Cameron, Robin E Offord, Oliver Hartley

Antimicrob Agents Chemother· October 2017

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A scalable low-cost cGMP process for clinical grade production of the HIV inhibitor 5P12-RANTES in Pichia pastoris.
Fabrice Cerini, Hubert Gaertner, Knut Madden, Ilya Tolstorukov, Scott Brown, Robin Offord

Protein Expr Purif· March 2016

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Heat-Stable Dry Powder Oxytocin Formulations for Delivery by Oral Inhalation.
Karine Fabio, Kieran Curley, Joseph Guarneri, Benoit Adamo, Brendan Laurenzi, Robin Offord

AAPS PharmSciTech· December 2015

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The next lease of life.
Robin Offord

Health Serv J· September 2014

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Using glycosaminoglycan/chemokine interactions for the long-term delivery of 5P12-RANTES in HIV prevention.
Nick X Wang, Scott F Sieg, Michael M Lederman, Robin E Offord, Oliver Hartley

Mol Pharm· October 2013

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CCR5 mutations distinguish N-terminal modifications of RANTES (CCL5) with agonist versus antagonist activity.
Won-Tak Choi, Rebecca Nedellec, Mia Coetzer, Philippe Colin, Bernard Lagane, Robin E Offord

J Virol· September 2012

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Lifeblood responds to criticisms in Welfare's personal view article.
Annya Stephens-Boal, Shelley Webster, Kim Carter, Ian M Franklin, Brian Gardner, Robin Offord

BMJ· January 2012

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Resistance to the CCR5 inhibitor 5P12-RANTES requires a difficult evolution from CCR5 to CXCR4 coreceptor use.
Rebecca Nedellec, Mia Coetzer, Michael M Lederman, Robin E Offord, Oliver Hartley

PLoS One· October 2011

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Circulating human CD4 and CD8 T cells do not have large intracellular pools of CCR5.
Heather A Pilch-Cooper, Scott F Sieg, Thomas J Hope, Ann Koons, Jean-Michel Escola, Robin Offord

Blood· July 2011

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"Resistance" to PSC-RANTES revisited: two mutations in human immunodeficiency virus type 1 HIV-1 SF162 or simian-human immunodeficiency virus SHIV SF162-p3 do not confer resistance.
Rebecca Nedellec, Mia Coetzer, Michael M Lederman, Robin E Offord, Oliver Hartley

J Virol· June 2010

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Topically applied recombinant chemokine analogues fully protect macaques from vaginal simian-human immunodeficiency virus challenge.
Ronald S Veazey, Binhua Ling, Linda C Green, Erin P Ribka, Jeffrey D Lifson, Robin Offord

J Infect Dis· May 2009

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Comparative proteomic study of the venom of the piscivorous cone snail Conus consors.
Daniel Biass, Sébastien Dutertre, Alain Gerbault, Jean-Louis Menou, Robin Offord

J Proteomics· March 2009

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Chemokine analogues show suitable stability for development as microbicides.
Fabrice Cerini, Alan Landay, Carolyne Gichinga, Michael M Lederman, Rebecca Flyckt, Robin E Offord

J Acquir Immune Defic Syndr· December 2008

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Highly potent, fully recombinant anti-HIV chemokines: reengineering a low-cost microbicide.
Hubert Gaertner, Fabrice Cerini, Jean-Michel Escola, Gabriel Kuenzi, Astrid Melotti, Robin Offord

Proc Natl Acad Sci U S A· November 2008

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Highly potent HIV inhibition: engineering a key anti-HIV structure from PSC-RANTES into MIP-1 beta/CCL4.
Hubert Gaertner, Olivier Lebeau, Irène Borlat, Fabrice Cerini, Brigitte Dufour, Robin Offord

Protein Eng Des Sel· February 2008

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Semisynthetic analogues of PSC-RANTES, a potent anti-HIV protein.
Hubert Gaertner, Robin Offord, Paolo Botti, Gabriel Kuenzi, Oliver Hartley

Bioconjug Chem· February 2008

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Microbicides and other topical strategies to prevent vaginal transmission of HIV.
Michael M Lederman, Robin E Offord, Oliver Hartley

Nat Rev Immunol· May 2006

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Engineering chemokines to develop optimized HIV inhibitors.
Oliver Hartley, Robin E Offord

Curr Protein Pept Sci· June 2005

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Medicinal chemistry applied to a synthetic protein: development of highly potent HIV entry inhibitors.
Oliver Hartley, Hubert Gaertner, Jill Wilken, Darren Thompson, Richard Fish, Robin Offord

Proc Natl Acad Sci U S A· November 2004

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Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5.
Michael M Lederman, Ronald S Veazey, Robin Offord, Donald E Mosier, Jason Dufour

Science· October 2004

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Economic evaluation of enoxaparin for the prevention of venous thromboembolism in acutely ill medical patients.
Robin Offord, Adam C Lloyd, Pippa Anderson, Andy Bearne

Pharm World Sci· August 2004

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