Publications by authors named "Robin Parks"

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Two randomised controlled phase 2 studies of the oral neutrophil elastase inhibitor alvelestat in alpha-1 antitrypsin deficiency.
J Michael Wells, Ingrid L Titlestad, Hanan Tanash, Alice M Turner, Kenneth R Chapman, Robin Parks

Eur Respir J· December 2025

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Extracellular vesicles efficiently deliver survival motor neuron protein to cells in culture.
Charlotte A René, Robin J Parks

Sci Rep· February 2025

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Report on the 6th Ottawa International Conference on Neuromuscular Disease & Biology - September 7-9, 2023, Ottawa, Canada.
Jodi Warman-Chardon, Bernard J Jasmin, Rashmi Kothary, Robin J Parks

J Neuromuscul Dis· February 2025

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Liver SMN restoration rescues the Smn mouse model of spinal muscular atrophy.
Emma R Sutton, Ariane Beauvais, Rebecca Yaworski, Yves De Repentigny, Aoife Reilly, Robin J Parks

EBioMedicine· December 2024

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Development and Characterization of an Oncolytic Human Adenovirus-Based Vector Co-Expressing the Adenovirus Death Protein and p14 Fusion-Associated Small Transmembrane Fusogenic Protein.
Kathy L Poulin, Ryan G Clarkin, Joshua Del Papa, Robin J Parks

Int J Mol Sci· November 2024

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Bioengineering extracellular vesicle cargo for optimal therapeutic efficiency.
Charlotte A René, Robin J Parks

Mol Ther Methods Clin Dev· June 2024

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Emerging and established biomarkers of oculopharyngeal muscular dystrophy.
Ian C Smith, Shaoni Chakraborty, Pierre R Bourque, Marcos L Sampaio, Gerd Melkus, Robin J Parks

Neuromuscul Disord· November 2023

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Inhibition of exchange proteins directly activated by cAMP as a strategy for broad-spectrum antiviral development.
Stephen Boulton, Mathieu J F Crupi, Siddharth Singh, Madalina E Carter-Timofte, Taha Azad, Robin J Parks

J Biol Chem· June 2023

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Expanding the Availability of Onasemnogene Abeparvovec to Older Patients: The Evolving Treatment Landscape for Spinal Muscular Atrophy.
Charlotte A René, Robin J Parks

Pharmaceutics· June 2023

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Human Adenovirus Gene Expression and Replication Is Regulated through Dynamic Changes in Nucleoprotein Structure throughout Infection.
Morgan R Jennings, Robin J Parks

Viruses· January 2023

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Report on the 5th Ottawa International Conference on Neuromuscular Disease & Biology -October 17-19, 2019, Ottawa, Canada.
Jodi Warman-Chardon, Bernard J Jasmin, Rashmi Kothary, Robin J Parks

J Neuromuscul Dis· October 2021

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The genome position of a therapeutic transgene strongly influences the level of expression in an armed oncolytic human adenovirus vector.
Ryan G Clarkin, Joshua Del Papa, Kathy L Poulin, Robin J Parks

Virology· September 2021

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Use of cell fusion proteins to enhance adenoviral vector efficacy as an anti-cancer therapeutic.
Joshua Del Papa, Ryan G Clarkin, Robin J Parks

Cancer Gene Ther· August 2021

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PKCα-mediated phosphorylation of the diacylglycerol kinase ζ MARCKS domain switches cell migration modes by regulating interactions with Rac1 and RhoA.
Ryan Ard, Jean-Christian Maillet, Elias Daher, Michael Phan, Radoslav Zinoviev, Robin J Parks

J Biol Chem· August 2021

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Label-free quantitative proteomic analysis of extracellular vesicles released from fibroblasts derived from patients with spinal muscular atrophy.
Justin Roberto, Kathy L Poulin, Robin J Parks, Panayiotis O Vacratsis

Proteomics· July 2021

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Nuclear HKII-P-p53 (Ser15) Interaction is a Prognostic Biomarker for Chemoresponsiveness and Glycolytic Regulation in Epithelial Ovarian Cancer.
Chae Young Han, David A Patten, Se Ik Kim, Jung Jin Lim, David W Chan, Robin J Parks

Cancers (Basel)· July 2021

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Delivery of Therapeutic Agents to the Central Nervous System and the Promise of Extracellular Vesicles.
Charlotte A René, Robin J Parks

Pharmaceutics· April 2021

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Identification of human adenovirus replication inhibitors from a library of small molecules targeting cellular epigenetic regulators.
Bratati Saha, Robin J Parks

Virology· March 2021

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Oncolytic Rhabdovirus Vaccine Boosts Chimeric Anti-DEC205 Priming for Effective Cancer Immunotherapy.
Fanny Tzelepis, Harsimrat Kaur Birdi, Anna Jirovec, Silvia Boscardin, Christiano Tanese de Souza, Robin J Parks

Mol Ther Oncolytics· December 2020

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Antiviral Effects of Curcumin on Adenovirus Replication.
Morgan R Jennings, Robin J Parks

Microorganisms· October 2020

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Curcumin as an Antiviral Agent.
Morgan R Jennings, Robin J Parks

Viruses· October 2020

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Fusion of Large Polypeptides to Human Adenovirus Type 5 Capsid Protein IX Can Compromise Virion Stability and DNA Packaging Capacity.
Kathy L Poulin, Emily R McFall, Grace Chan, Natacha B Provost, Carin Christou, Robin J Parks

J Virol· August 2020

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Recent Advances in Novel Antiviral Therapies against Human Adenovirus.
Bratati Saha, Robin J Parks

Microorganisms· August 2020

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Development of a novel screening platform for the identification of small molecule inhibitors of human adenovirus.
Bratati Saha, Oliver Varette, William L Stanford, Jean-Simon Diallo, Robin J Parks

Virology· December 2019

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p53 Promotes chemoresponsiveness by regulating hexokinase II gene transcription and metabolic reprogramming in epithelial ovarian cancer.
Chae Young Han, David A Patten, Seung Gee Lee, Robin J Parks, David W Chan

Mol Carcinog· November 2019

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