Publications by authors named "Robin Polt"

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The angiotensin (1-7) glycopeptide PNA5 improves cognition in a chronic progressive mouse model of Parkinson's disease through modulation of neuroinflammation.
Kelsey Bernard, Jesus A Mota, Paige Wene, Mandi J Corenblum, Juben L Saez, Robin Polt

Exp Neurol· November 2024

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Cyclic Glycopeptide Analogs of Endomorphin-1 Provide Highly Effective Antinociception in Male and Female Mice.
James E Zadina, Lajos Z Szabo, Fahad Al-Obeidi, Xing Zhang, Leticia Ferreira Nakatani, Robin Polt

ACS Med Chem Lett· October 2024

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PNA5, A Novel Mas Receptor Agonist, Improves Neurovascular and Blood-Brain-Barrier Function in a Mouse Model of Vascular Cognitive Impairment and Dementia.
Christina Hoyer-Kimura, Meredith Hay, John P Konhilas, Helena W Morrison, Methawasin Methajit, Robin Polt

Aging Dis· August 2024

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PACAP glycosides promote cell outgrowth in vitro and reduce infarct size after stroke in a preclinical model.
Kelsey Bernard, Denali Dickson, Bobbi L Anglin, M Leandro Heien, Robin Polt

Neurosci Lett· July 2024

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Design and synthesis of oxytocin glycosides for the treatment of pain and substance use disorder.
Hannah J Goodman, Lajos Z Szabò, Samuel M Sugerman, Andriy Myloserdnyy, Robin Polt

Methods Enzymol· June 2024

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PNA6, a Lactosyl Analogue of Angiotensin-(1-7), Reverses Pain Induced in Murine Models of Inflammation, Chemotherapy-Induced Peripheral Neuropathy, and Metastatic Bone Disease.
Maha I Sulaiman, Wafaa Alabsi, Lajos Szabo, Meredith Hay, Robin Polt

Int J Mol Sci· October 2023

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Structure-Based Design of Glycosylated Oxytocin Analogues with Improved Selectivity and Antinociceptive Activity.
Lajos Z Szabó, Parthasaradhireddy Tanguturi, Hannah J Goodman, Sára Sprőber, Chenxi Liu, Robin Polt

ACS Med Chem Lett· February 2023

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Nose-to-Brain Delivery of Therapeutic Peptides as Nasal Aerosols.
Wafaa Alabsi, Basanth Babu Eedara, David Encinas-Basurto, Robin Polt, Heidi M Mansour

Pharmaceutics· September 2022

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Glycosylated Ang-(1-7) MasR Agonist Peptide Poly Lactic-co-Glycolic Acid (PLGA) Nanoparticles and Microparticles in Cognitive Impairment: Design, Particle Preparation, Physicochemical Characterization, and In Vitro Release.
David Encinas-Basurto, John P Konhilas, Robin Polt, Meredith Hay, Heidi M Mansour

Pharmaceutics· March 2022

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Design and Synthesis of Brain Penetrant Glycopeptide Analogues of PACAP With Neuroprotective Potential for Traumatic Brain Injury and Parkinsonism.
Christopher R Apostol, Kelsey Bernard, Parthasaradhireddy Tanguturi, Gabriella Molnar, Mitchell J Bartlett, Robin Polt

Front Drug Discov (Lausanne)· January 2022

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Neurofilament light: a possible prognostic biomarker for treatment of vascular contributions to cognitive impairment and dementia.
Christina Hoyer-Kimura, John P Konhilas, Heidi M Mansour, Robin Polt, Kristian P Doyle

J Neuroinflammation· October 2021

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Angiotensin-(1-7) Peptide Hormone Reduces Inflammation and Pathogen Burden during Infection in Mice.
Katie L Collins, Usir S Younis, Sasipa Tanyaratsrisakul, Robin Polt, Meredith Hay

Pharmaceutics· October 2021

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Synthesis and In Vitro Characterization of Glycopeptide Drug Candidates Related to PACAP.
Christopher R Apostol, Parthasaradhireddy Tanguturi, Lajos Z Szabò, Daniel Varela, Thiago Gilmartin, Robin Polt

Molecules· August 2021

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Synthesis, Physicochemical Characterization, In Vitro 2D/3D Human Cell Culture, and In Vitro Aerosol Dispersion Performance of Advanced Spray Dried and Co-Spray Dried Angiotensin (1-7) Peptide and PNA5 with Trehalose as Microparticles/Nanoparticles for Targeted Respiratory Delivery as Dry Powder Inhalers.
Wafaa Alabsi, Maria F Acosta, Fahad A Al-Obeidi, Meredith Hay, Robin Polt

Pharmaceutics· August 2021

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Inhalation Delivery for the Treatment and Prevention of COVID-19 Infection.
Basanth Babu Eedara, Wafaa Alabsi, David Encinas-Basurto, Robin Polt, Julie G Ledford

Pharmaceutics· July 2021

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Spray-Dried Inhalable Powder Formulations of Therapeutic Proteins and Peptides.
Basanth Babu Eedara, Wafaa Alabsi, David Encinas-Basurto, Robin Polt, Heidi M Mansour

AAPS PharmSciTech· June 2021

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The Delta-Specific Opioid Glycopeptide BBI-11008: CNS Penetration and Behavioral Analysis in a Preclinical Model of Levodopa-Induced Dyskinesia.
Mitchell J Bartlett, Omar S Mabrouk, Lajos Szabò, Andrew J Flores, Kate L Parent, Robin Polt

Int J Mol Sci· December 2020

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Organic Solution Advanced Spray-Dried Microparticulate/Nanoparticulate Dry Powders of Lactomorphin for Respiratory Delivery: Physicochemical Characterization, In Vitro Aerosol Dispersion, and Cellular Studies.
Wafaa Alabsi, Fahad A Al-Obeidi, Robin Polt, Heidi M Mansour

Pharmaceutics· December 2020

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Glycopeptide drugs: A pharmacological dimension between "Small Molecules" and "Biologics".
Christopher R Apostol, Meredith Hay, Robin Polt

Peptides· September 2020

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Biodegradability and Toxicity of Cellobiosides and Melibiosides.
David E Hogan, Fei Tian, Scott W Malm, Laurel L Kegel, Lajos Z Szabo, Robin Polt

J Surfactants Deterg· July 2020

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Behavioral pharmacology of the mixed-action delta-selective opioid receptor agonist BBI-11008: studies on acute, inflammatory and neuropathic pain, respiration, and drug self-administration.
Glenn W Stevenson, Denise Giuvelis, James Cormier, Katherine Cone, Phillip Atherton, Robin Polt

Psychopharmacology (Berl)· April 2020

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Highly-selective µ-opioid receptor antagonism does not block L-DOPA-induced dyskinesia in a rodent model.
Mitchell J Bartlett, Lisa Y So, Lajos Szabò, David P Skinner, Kate L Parent, Robin Polt

BMC Res Notes· March 2020

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Docking Studies of Fingolimod and S1P Agonists.
Alexander Marciniak, Sara M Camp, Joe G N Garcia, Robin Polt

Front Pharmacol· March 2020

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Sphingosine-1-phosphate receptor-independent lung endothelial cell barrier disruption induced by FTY720 regioisomers.
Sara M Camp, Alexander Marciniak, Eddie T Chiang, Alexander N Garcia, Robert Bittman, Robin Polt

Pulm Circ· February 2020

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A Novel Angiotensin-(1-7) Glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation-Related Memory Dysfunction.
Meredith Hay, Robin Polt, Michael L Heien, Todd W Vanderah, Tally M Largent-Milnes

J Pharmacol Exp Ther· April 2019

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