Publications by authors named "Robyn A Sharples"

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Malaria parasite DNA-harbouring vesicles activate cytosolic immune sensors.
Xavier Sisquella, Yifat Ofir-Birin, Matthew A Pimentel, Lesley Cheng, Paula Abou Karam, Robyn A Sharples

Nat Commun· December 2017

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BRAF inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells.
Taral R Lunavat, Lesley Cheng, Berglind O Einarsdottir, Roger Olofsson Bagge, Somsundar Veppil Muralidharan, Robyn A Sharples

Proc Natl Acad Sci U S A· July 2017

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Defining the purity of exosomes required for diagnostic profiling of small RNA suitable for biomarker discovery.
Camelia Quek, Shayne A Bellingham, Chol-Hee Jung, Benjamin J Scicluna, Mitch C Shambrook, Robyn A Sharples

RNA Biol· February 2017

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Small RNA deep sequencing discriminates subsets of extracellular vesicles released by melanoma cells--Evidence of unique microRNA cargos.
Taral R Lunavat, Lesley Cheng, Dae-Kyum Kim, Joydeep Bhadury, Su Chul Jang, Robyn A Sharples

RNA Biol· May 2016

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Gene dysregulation is restored in the Parkinson's disease MPTP neurotoxic mice model upon treatment of the therapeutic drug Cu(II)(atsm).
Lesley Cheng, Camelia Y J Quek, Lin W Hung, Robyn A Sharples, Nicki A Sherratt

Sci Rep· March 2016

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Site of fluorescent label modifies interaction of melittin with live cells and model membranes.
Elaheh Jamasbi, Giuseppe D Ciccotosto, Julien Tailhades, Roy M Robins-Browne, Cathryn L Ugalde, Robyn A Sharples

Biochim Biophys Acta· October 2015

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Melittin peptides exhibit different activity on different cells and model membranes.
Elaheh Jamasbi, Steven Batinovic, Robyn A Sharples, Marc-Antoine Sani, Roy Michael Robins-Browne

Amino Acids· December 2014

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Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood.
Lesley Cheng, Robyn A Sharples, Benjamin J Scicluna, Andrew F Hill

J Extracell Vesicles· March 2014

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Mouse-adapted sporadic human Creutzfeldt-Jakob disease prions propagate in cell culture.
Victoria A Lawson, Laura J Vella, James D Stewart, Robyn A Sharples, Helen Klemm

Int J Biochem Cell Biol· December 2008

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Activation of epidermal growth factor receptor by metal-ligand complexes decreases levels of extracellular amyloid beta peptide.
Katherine A Price, Gulay Filiz, Aphrodite Caragounis, Tai Du, Katrina M Laughton, Robyn A Sharples

Int J Biochem Cell Biol· September 2008

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Inhibition of gamma-secretase causes increased secretion of amyloid precursor protein C-terminal fragments in association with exosomes.
Robyn A Sharples, Laura J Vella, Rebecca M Nisbet, Ryan Naylor, Keyla Perez

FASEB J· May 2008

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The role of exosomes in the processing of proteins associated with neurodegenerative diseases.
Laura J Vella, Robyn A Sharples, Rebecca M Nisbet, Roberto Cappai, Andrew F Hill

Eur Biophys J· March 2008

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Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide.
Paul S Donnelly, Aphrodite Caragounis, Tai Du, Katrina M Laughton, Irene Volitakis, Robyn A Sharples

J Biol Chem· February 2008

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Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.
Aphrodite Caragounis, Tai Du, Gulay Filiz, Katrina M Laughton, Irene Volitakis, Robyn A Sharples

Biochem J· November 2007

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Degradation of the Alzheimer disease amyloid beta-peptide by metal-dependent up-regulation of metalloprotease activity.
Anthony R White, Tai Du, Katrina M Laughton, Irene Volitakis, Robyn A Sharples

J Biol Chem· June 2006

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Dopamine promotes alpha-synuclein aggregation into SDS-resistant soluble oligomers via a distinct folding pathway.
Roberto Cappai, Su-Ling Leck, Deborah J Tew, Nicholas A Williamson, David P Smith, Robyn A Sharples

FASEB J· August 2005

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Transition-state analogue gamma-secretase inhibitors stabilize a 900 kDa presenilin/nicastrin complex.
Geneviève Evin, Louise D Canterford, David E Hoke, Robyn A Sharples, Janetta G Culvenor

Biochemistry· March 2005

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Expression of truncated presenilin 2 splice variant in Alzheimer's disease, bipolar disorder, and schizophrenia brain cortex.
Margaret J Smith, Robyn A Sharples, Geneviève Evin, Catriona A McLean, Brian Dean

Brain Res Mol Brain Res· August 2004

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Alternative transcripts of presenilin-1 associated with frontotemporal dementia.
Geneviève Evin, Margaret J Smith, Angela Tziotis, Catriona McLean, Louise Canterford, Robyn A Sharples

Neuroreport· May 2002

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Alternative transcripts of presenilin-1 associated with frontotemporal dementia.
Geneviève Evin, Margaret J Smith, Angela Tziotis, Catriona McLean, Louise Canterford, Robyn A Sharples

Neuroreport· April 2002

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