Publications by authors named "Roderick C Slieker"

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Cell Type-Specific Expression of Long Noncoding RNAs in Human Diabetic Kidneys Identifies TARID as a Key Regulator of Podocyte Function.
Juliette A de Klerk, Roderick C Slieker, Wilson C Parker, Haojia Wu, Yoshiharu Muto

Diabetes· November 2025

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Pyroglutamation of cell surface proteins CD47 and TRP1 by glutaminyl cyclase modulates therapeutic antibody binding.
Anneloes van der Plas-van Duijn, Levi M T Winkelman, Claire Lensen, Maaike van Duivendijk, Ian Derksen, Roderick C Slieker

Commun Biol· November 2025

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Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, Roderick C Slieker

Nat Med· September 2025

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Targeting long non-coding RNA preserves endothelial cell integrity and protects against kidney fibrosis.
Qiao Zhao, Loïs A K van der Pluijm, Morgane Gourvest, Atefeh Lafzi, Daniel Peled, Roderick C Slieker

Mol Ther Nucleic Acids· September 2025

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The influence of metformin treatment on the circulating proteome.
Ben Connolly, Laura McCreight, Roderick C Slieker, Khaled F Bedair, Louise Donnelly

EBioMedicine· August 2025

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Single-cell spatial transcriptomics unravels cell states and ecosystems associated with clinical response to immunotherapy.
Ziena Abdulrahman, Roderick C Slieker, Daniel McGuire, Marij J P Welters, Mariette I E van Poelgeest

J Immunother Cancer· March 2025

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Trajectories of clinical characteristics, complications and treatment choices in data-driven subgroups of type 2 diabetes.
Xinyu Li, Louise A Donnelly, Roderick C Slieker, Joline W J Beulens, Leen M 't Hart

Diabetologia· July 2024

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Branched-chain amino acid levels are inversely associated with incident and prevalent chronic kidney disease in people with type 2 diabetes.
Juliette A de Klerk, Roel Bijkerk, Joline W J Beulens, Anton Jan van Zonneveld, Mirte Muilwijk, Roderick C Slieker

Diabetes Obes Metab· May 2024

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An omics-based machine learning approach to predict diabetes progression: a RHAPSODY study.
Roderick C Slieker, Magnus Münch, Louise A Donnelly, Gerard A Bouland, Iulian Dragan

Diabetologia· May 2024

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Apolipoprotein-CIII O-Glycosylation Is Associated with Micro- and Macrovascular Complications of Type 2 Diabetes.
Annemieke Naber, Daniel Demus, Roderick C Slieker, Simone Nicolardi, Joline W J Beulens

Int J Mol Sci· May 2024

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Reassessing human MHC-I genetic diversity in T cell studies.
Roderick C Slieker, Daniël O Warmerdam, Maarten H Vermeer, Remco van Doorn, Mirjam H M Heemskerk

Sci Rep· April 2024

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Perinatal exposure to the immune-suppressant di-n-octyltin dichloride affects brain development in rats.
Didima M G de Groot, Louisa Linders, Reinier Kayser, Rianne Nederlof, Celine de Esch, Roderick C Slieker

Toxicol Mech Methods· March 2024

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Multi-omics subgroups associated with glycaemic deterioration in type 2 diabetes: an IMI-RHAPSODY Study.
Shiying Li, Iulian Dragan, Van Du T Tran, Chun Ho Fung, Dmitry Kuznetsov, Roderick C Slieker

Front Endocrinol (Lausanne)· March 2024

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Genome-wide association study of serum magnesium in type 2 diabetes.
Lynette J Oost, Roderick C Slieker, Marieke T Blom, Leen M 't Hart, Joost G J Hoenderop

Genes Nutr· January 2024

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IgG N-glycans are associated with prevalent and incident complications of type 2 diabetes.
Elham Memarian, Ralph Heijmans, Roderick C Slieker, Adriana Sierra, Olga Gornik

Diabetes Metab Res Rev· October 2023

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The inactive X chromosome accumulates widespread epigenetic variability with age.
Yunfeng Liu, Lucy Sinke, Thomas H Jonkman, Roderick C Slieker,

Clin Epigenetics· August 2023

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Potential Value of Identifying Type 2 Diabetes Subgroups for Guiding Intensive Treatment: A Comparison of Novel Data-Driven Clustering With Risk-Driven Subgroups.
Xinyu Li, Anoukh van Giessen, James Altunkaya, Roderick C Slieker, Joline W J Beulens

Diabetes Care· July 2023

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Altered blood gene expression in the obesity-related type 2 diabetes cluster may be causally involved in lipid metabolism: a Mendelian randomisation study.
Juliette A de Klerk, Joline W J Beulens, Hailiang Mei, Roel Bijkerk, Anton Jan van Zonneveld, Roderick C Slieker

Diabetologia· June 2023

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Author Correction: The power of genetic diversity in genome-wide association studies of lipids.
Sarah E Graham, Shoa L Clarke, Kuan-Han H Wu, Stavroula Kanoni, Greg J M Zajac, Roderick C Slieker

Nature· June 2023

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Identification of biomarkers for glycaemic deterioration in type 2 diabetes.
Roderick C Slieker, Louise A Donnelly, Elina Akalestou, Livia Lopez-Noriega, Rana Melhem

Nat Commun· May 2023

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Lipid-induced transcriptomic changes in blood link to lipid metabolism and allergic response.
Koen F Dekkers, Roderick C Slieker, Andreea Ioan-Facsinay, Maarten van Iterson,

Nat Commun· February 2023

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Therapeutic Strategies for Targeting CDKN2A Loss in Melanoma.
Inger Z M Kreuger, Roderick C Slieker, Tim van Groningen, Remco van Doorn

J Invest Dermatol· January 2023

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Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis.
Stavroula Kanoni, Sarah E Graham, Yuxuan Wang, Ida Surakka, Shweta Ramdas, Roderick C Slieker

Genome Biol· December 2022

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A saturated map of common genetic variants associated with human height.
Loïc Yengo, Sailaja Vedantam, Eirini Marouli, Julia Sidorenko, Eric Bartell, Roderick C Slieker

Nature· October 2022

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A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids.
Shweta Ramdas, Jonathan Judd, Sarah E Graham, Stavroula Kanoni, Yuxuan Wang, Roderick C Slieker

Am J Hum Genet· August 2022

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