Publications by authors named "Roderick J Flower"

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Loss of hypothermic and anti-pyretic action of paracetamol in cyclooxygenase-1 knockout mice is indicative of inhibition of cyclooxygenase-1 variant enzymes.
Samir S Ayoub, Roderick J Flower

Eur J Pharmacol· October 2019

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Oiling the wheels of discovery.
Roderick J Flower

Br J Pharmacol· April 2019

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The Anti-allergic Cromones: Past, Present, and Future.
Ajantha Sinniah, Samia Yazid, Roderick J Flower

Front Pharmacol· November 2017

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Mast cells mediate early neutrophil recruitment and exhibit anti-inflammatory properties via the formyl peptide receptor 2/lipoxin A receptor.
Ellen L Hughes, Felix Becker, Roderick J Flower, Julia C Buckingham, Felicity N E Gavins

Br J Pharmacol· July 2017

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Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen.
Anne L Robertson, Nikolay V Ogryzko, Katherine M Henry, Catherine A Loynes, Matthew J Foulkes, Roderick J Flower

Dis Model Mech· June 2016

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Definition of a Novel Pathway Centered on Lysophosphatidic Acid To Recruit Monocytes during the Resolution Phase of Tissue Inflammation.
Simon McArthur, Thomas Gobbetti, Dennis H M Kusters, Christopher P Reutelingsperger, Roderick J Flower

J Immunol· August 2015

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Annexin-A1 restricts Th17 cells and attenuates the severity of autoimmune disease.
Samia Yazid, Peter J Gardner, Livia Carvalho, Colin J Chu, Roderick J Flower

J Autoimmun· April 2015

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Identification of a novel recycling sequence in the C-tail of FPR2/ALX receptor: association with cell protection from apoptosis.
Dawn Thompson, Simon McArthur, James N Hislop, Roderick J Flower, Mauro Perretti

J Biol Chem· December 2014

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Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis.
Thomas Gobbetti, Sina M Coldewey, Jianmin Chen, Simon McArthur, Pauline le Faouder, Roderick J Flower

Proc Natl Acad Sci U S A· December 2014

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Annexin A1 mediates hydrogen sulfide properties in the control of inflammation.
Vincenzo Brancaleone, Emma Mitidieri, Roderick J Flower, Giuseppe Cirino, Mauro Perretti

J Pharmacol Exp Ther· October 2014

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The outsider: the rogue scientist as terrorist.
Roderick John Flower

J Med Ethics· April 2014

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Pharmacology 2.0.
Roderick J Flower

Br J Clin Pharmacol· November 2013

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Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses.
Sadani N Cooray, Thomas Gobbetti, Trinidad Montero-Melendez, Simon McArthur, Dawn Thompson, Roderick J Flower

Proc Natl Acad Sci U S A· November 2013

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A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation.
Vincenzo Brancaleone, Thomas Gobbetti, Nicolas Cenac, Pauline le Faouder, Bartomeu Colom, Roderick J Flower

Blood· July 2013

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Attenuation of plasma annexin A1 in human obesity.
Anna Kosicka, Adam D Cunliffe, Richard Mackenzie, M Gulrez Zariwala, Mauro Perretti, Roderick J Flower

FASEB J· January 2013

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Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: receptor-dependent actions.
Lucy V Norling, Jesmond Dalli, Roderick J Flower, Charles N Serhan, Mauro Perretti

Arterioscler Thromb Vasc Biol· August 2012

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Annexin A1 interaction with the FPR2/ALX receptor: identification of distinct domains and downstream associated signaling.
Stefania Bena, Vincenzo Brancaleone, Ji Ming Wang, Mauro Perretti, Roderick J Flower

J Biol Chem· July 2012

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Endogenous annexin A1 counter-regulates bleomycin-induced lung fibrosis.
Amílcar S Damazo, André Lf Sampaio, Cintia Mag Nakata, Roderick J Flower, Mauro Perretti

BMC Immunol· October 2011

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Paracetamol-induced hypothermia is independent of cannabinoids and transient receptor potential vanilloid-1 and is not mediated by AM404.
Samir S Ayoub, Gareth Pryce, Michael P Seed, Christopher Bolton, Roderick J Flower

Drug Metab Dispos· September 2011

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Cutting edge: Humanized nano-proresolving medicines mimic inflammation-resolution and enhance wound healing.
Lucy V Norling, Matthew Spite, Rong Yang, Roderick J Flower, Mauro Perretti

J Immunol· May 2011

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Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature.
Vincenzo Brancaleone, Jesmond Dalli, Stefania Bena, Roderick J Flower, Giuseppe Cirino

J Immunol· April 2011

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Targeting the melanocortin receptor system for anti-stroke therapy.
Paul M Holloway, Helen K Smith, Derek Renshaw, Roderick J Flower, Stephen J Getting

Trends Pharmacol Sci· February 2011

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Anti-allergic drugs and the Annexin-A1 system.
Samia Yazid, Samir S Ayoub, Egle Solito, Simon McArthur, Phuong Vo, Roderick J Flower

Pharmacol Rep· November 2010

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In vitro cyclo-oxygenase expression and activity protocols: Introduction to Part I.
Roderick J Flower

Methods Mol Biol· October 2010

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Antiallergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization.
Samia Yazid, Giovanna Leoni, Stephen J Getting, Dianne Cooper, Egle Solito, Roderick J Flower

Arterioscler Thromb Vasc Biol· September 2010

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