Publications by authors named "Roderick MacKinnon"

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T
The configurational length scale in the self-assembly and modulation of higher-order transient protein structures.
Christoph A Haselwandter, Roderick MacKinnon

Proc Natl Acad Sci U S A· November 2025

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Molecular contacts in self-assembling clusters of membrane proteins.
Venkata Shiva Mandala, Ziao Fu, Roderick MacKinnon

Proc Natl Acad Sci U S A· July 2025

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Electric field-induced pore constriction in the human K2.1 channel.
Venkata Shiva Mandala, Roderick MacKinnon

Proc Natl Acad Sci U S A· May 2025

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Higher-order transient structures and the principle of dynamic connectivity in membrane signaling.
Yuxi Zhang, Roderick MacKinnon

Proc Natl Acad Sci U S A· January 2025

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Higher-order transient membrane protein structures.
Yuxi Zhang, Hisham Mazal, Venkata Shiva Mandala, Gonzalo Pérez-Mitta, Vahid Sondoghdar, Roderick MacKinnon

Proc Natl Acad Sci U S A· January 2025

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Structure of the flotillin complex in a native membrane environment.
Ziao Fu, Roderick MacKinnon

Proc Natl Acad Sci U S A· July 2024

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Freestanding bilayer microscope for single-molecule imaging of membrane proteins.
Gonzalo Pérez-Mitta, Yeliz Sezgin, Weiwei Wang, Roderick MacKinnon

Sci Adv· June 2024

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The mechanism of regulation of -catalyzed hydrolysis.
Maria E Falzone, Roderick MacKinnon

Proc Natl Acad Sci U S A· November 2023

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The mechanism of regulation of -catalyzed hydrolysis.
Maria E Falzone, Roderick MacKinnon

bioRxiv· August 2023

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Membrane protein isolation and structure determination in cell-derived membrane vesicles.
Xiao Tao, Chen Zhao, Roderick MacKinnon

Proc Natl Acad Sci U S A· May 2023

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activates hydrolysis by recruiting and orienting on the membrane surface.
Maria E Falzone, Roderick MacKinnon

Proc Natl Acad Sci U S A· May 2023

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The membrane electric field regulates the PIP-binding site to gate the KCNQ1 channel.
Venkata Shiva Mandala, Roderick MacKinnon

Proc Natl Acad Sci U S A· May 2023

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Freestanding lipid bilayer tensiometer for the study of mechanosensitive ion channels.
Gonzalo Pérez-Mitta, Roderick MacKinnon

Proc Natl Acad Sci U S A· March 2023

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Structural and functional analyses of a GPCR-inhibited ion channel TRPM3.
Chen Zhao, Roderick MacKinnon

Neuron· January 2023

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Piezo1 as a force-through-membrane sensor in red blood cells.
George Vaisey, Priyam Banerjee, Alison J North, Christoph A Haselwandter, Roderick MacKinnon

Elife· December 2022

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Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Venkata Shiva Mandala, Roderick MacKinnon

Proc Natl Acad Sci U S A· November 2022

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Quantitative prediction and measurement of Piezo's membrane footprint.
Christoph A Haselwandter, Yusong R Guo, Ziao Fu, Roderick MacKinnon

Proc Natl Acad Sci U S A· October 2022

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Elastic properties and shape of the Piezo dome underlying its mechanosensory function.
Christoph A Haselwandter, Yusong R Guo, Ziao Fu, Roderick MacKinnon

Proc Natl Acad Sci U S A· October 2022

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Correlation between structure and function in phosphatidylinositol lipid-dependent Kir2.2 gating.
Yuxi Zhang, Xiao Tao, Roderick MacKinnon

Proc Natl Acad Sci U S A· March 2022

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Molecular structure of an open human K channel.
Chen Zhao, Roderick MacKinnon

Proc Natl Acad Sci U S A· November 2021

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Analysis of the mechanosensor channel functionality of TACAN.
Yiming Niu, Xiao Tao, George Vaisey, Paul Dominic B Olinares, Hanan Alwaseem, Roderick MacKinnon

Elife· August 2021

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Cryo-EM analysis of PIP regulation in mammalian GIRK channels.
Yiming Niu, Xiao Tao, Kouki K Touhara, Roderick MacKinnon

Elife· August 2020

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Structural Basis of Human KCNQ1 Modulation and Gating.
Ji Sun, Roderick MacKinnon

Cell· January 2020

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Voltage Sensor Movements during Hyperpolarization in the HCN Channel.
Chia-Hsueh Lee, Roderick MacKinnon

Cell· December 2019

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Molecular structures of the human Slo1 K channel in complex with β4.
Xiao Tao, Roderick MacKinnon

Elife· December 2019

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