Publications by authors named "Rodney L Johnson"

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Ligand-induced expansion of the S1' site in the anthrax toxin lethal factor.
Kimberly M Maize, Elbek K Kurbanov, Rodney L Johnson, Elizabeth Ambrose Amin, Barry C Finzel

FEBS Lett· December 2015

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Probing the S2' Subsite of the Anthrax Toxin Lethal Factor Using Novel N-Alkylated Hydroxamates.
Elbek K Kurbanov, Ting-Lan Chiu, Jonathan Solberg, Subhashree Francis, Kimberly M Maize, Rodney L Johnson

J Med Chem· November 2015

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Change in expression of vesicular protein synapsin II by chronic treatment with D2 allosteric modulator PAOPA.
Dipannita Basu, Yuxin Tian, Patricia Hui, Jayant Bhandari, Rodney L Johnson

Peptides· April 2015

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Anthrax toxin lethal factor domain 3 is highly mobile and responsive to ligand binding.
Kimberly M Maize, Elbek K Kurbanov, Teresa De La Mora-Rey, Todd W Geders, Dong Jin Hwang, Rodney L Johnson

Acta Crystallogr D Biol Crystallogr· November 2014

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Effects of the dopamine D2 allosteric modulator, PAOPA, on the expression of GRK2, arrestin-3, ERK1/2, and on receptor internalization.
Dipannita Basu, Yuxin Tian, Jayant Bhandari, Jian Ru Jiang, Patricia Hui, Rodney L Johnson

PLoS One· April 2014

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Preclinical pharmacokinetic and toxicological evaluation of MIF-1 peptidomimetic, PAOPA: examining the pharmacology of a selective dopamine D2 receptor allosteric modulator for the treatment of schizophrenia.
Mattea L Tan, Dipannita Basu, Jacek M Kwiecien, Rodney L Johnson, Ram K Mishra

Peptides· April 2013

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PAOPA, a potent dopamine D2 receptor allosteric modulator, prevents and reverses behavioral and biochemical abnormalities in an amphetamine-sensitized preclinical animal model of schizophrenia.
Michael G R Beyaert, Ritesh P Daya, Bailey A Dyck, Rodney L Johnson, Ram K Mishra

Eur Neuropsychopharmacol· March 2013

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Development of peptidomimetic ligands of Pro-Leu-Gly-NH(2) as allosteric modulators of the dopamine D(2) receptor.
Swapna Bhagwanth, Ram K Mishra, Rodney L Johnson

Beilstein J Org Chem· February 2013

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Transformation of Pro-Leu-Gly-NH2 peptidomimetic positive allosteric modulators of the dopamine D2 receptor into negative modulators.
Swapna Bhagwanth, Satyendra Mishra, Ritesh Daya, Jordan Mah, Ram K Mishra, Rodney L Johnson

ACS Chem Neurosci· April 2012

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Specific binding of photoaffinity-labeling peptidomimetics of Pro-Leu-Gly-NH2 to the dopamine D2L receptor: evidence for the allosteric modulation of the dopamine receptor.
Amandeep Mann, Vaneeta Verma, Dipannita Basu, Kevin J Skoblenick, Michael G R Beyaert, Rodney L Johnson

Eur J Pharmacol· September 2010

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Evaluation of Density Functionals, SCC-DFTB, Neglect of Diatomic Differential Overlap (NDDO) Models and Molecular Mechanics Methods for Prolyl-Leucyl-Glycinamide (PLG) and Structural Derivatives.
Richard L Wood, Brendan J Young-Dixon, Abhrajeet Roy, Bryant C Gay, Rodney L Johnson

Theochem· March 2010

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Allosteric modulation of the dopamine D2 receptor by Pro-Leu-Gly-NH2 peptidomimetics constrained in either a polyproline II helix or a type II beta-turn conformation.
Bhooma Raghavan, Kevin J Skoblenick, Swapna Bhagwanth, Niran Argintaru, Ram K Mishra, Rodney L Johnson

J Med Chem· April 2009

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Heterogeneity of reproductive aging in free-ranging female rhesus macaques.
Rodney L Johnson, Ellen Kapsalis

Interdiscip Top Gerontol· September 2008

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Allosteric modulation of the dopamine receptor by conformationally constrained type VI beta-turn peptidomimetics of Pro-Leu-Gly-NH2.
Ashish P Vartak, Kevin Skoblenick, Nancy Thomas, Ram K Mishra, Rodney L Johnson

J Med Chem· December 2007

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MIF-1 and its peptidomimetic analogs attenuate haloperidol-induced vacuous chewing movements and modulate apomorphine-induced rotational behavior in 6-hydroxydopamine-lesioned rats.
Jessica M Castellano, Jody Batrynchuk, Kristine Dolbeare, Vaneeta Verma, Amandeep Mann, Rodney L Johnson

Peptides· October 2007

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Concerted synthesis of a spirobicyclic type-VI beta-turn mimic of Pro-Pro-Pro-NH2.
Ashish P Vartak, Rodney L Johnson

Org Lett· March 2006

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Short stereoselective synthesis of alpha-substituted gamma-lactams.
Bhooma Raghavan, Rodney L Johnson

J Org Chem· March 2006

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Design and synthesis of photoaffinity-labeling ligands of the L-prolyl-L-leucylglycinamide binding site involved in the allosteric modulation of the dopamine receptor.
Abigail Fisher, Amandeep Mann, Vaneeta Verma, Nancy Thomas, Ram K Mishra, Rodney L Johnson

J Med Chem· January 2006

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Modulation of agonist binding to human dopamine receptor subtypes by L-prolyl-L-leucyl-glycinamide and a peptidomimetic analog.
Vaneeta Verma, Amandeep Mann, Willard Costain, Giuseppe Pontoriero, Jessica M Castellano, Rodney L Johnson

J Pharmacol Exp Ther· December 2005

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Synthesis of pipecolic acid-based spiro bicyclic lactam scaffolds as beta-turn mimics.
Ravindranadh V Somu, Rodney L Johnson

J Org Chem· July 2005

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2,3-Ethylene- and 2,3-trimethylene-bridged analogues of the group III metabotropic glutamate receptor ligand 2-amino-4-phosphonobutanoic acid.
Rodney L Johnson, Kolluri S S P Rao

Bioorg Med Chem Lett· January 2005

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Stereoselective synthesis of alpha,alpha'-biprolines.
Ashish P Vartak, Victor G Young, Rodney L Johnson

Org Lett· January 2005

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Iso-lactam and reduced amide analogues of the peptidomimetic dopamine receptor modulator 3(R)-[(2(S)-pyrrolidinylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide.
Kristine Dolbeare, Giuseppe F Pontoriero, Suresh K Gupta, Ram K Mishra, Rodney L Johnson

Bioorg Med Chem· September 2003

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Synthesis and dopamine receptor modulating activity of 3-substituted gamma-lactam peptidomimetics of L-prolyl-L-leucyl-glycinamide.
Kristine Dolbeare, Giuseppe F Pontoriero, Suresh K Gupta, Ram K Mishra, Rodney L Johnson

J Med Chem· February 2003

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Control of postpartum mating behavior in free-ranging rhesus monkeys.
Iqbal Malik, Rodney L Johnson, Carol M Berman

Am J Primatol· January 1992

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