Publications by authors named "Rodney Lea"

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Regional autozygosity association with albumin-to-creatinine ratio reveals a novel FTO region in an Indigenous Australian population.
Vignesh Arunachalam, Kim N Tran, Wendy Hoy, Rodney A Lea, Shivashankar H Nagaraj

Eur J Hum Genet· December 2025

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Brain Age.
Rodney Lea, Stasson Lea, Gavin Giovannoni, Chris Hawkes, Michael Levy

Mult Scler Relat Disord· December 2025

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Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Roelof A J Smit, Kaitlin H Wade, Qin Hui, Joshua D Arias, Xianyong Yin, Ghislain Rocheleau, Rodney Lea, Maria Sabater-Lleal, Eleanor M Simonsick

Nat Med· September 2025

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A longitudinal investigation of the cerebral venous hemodynamics in multiple sclerosis using computational fluid dynamics.
Alexander Robert Bateman, Jeannette Lechner-Scott, Tracie Barber, Grant Alexander Bateman, Saadallah Ramadan, Rodney Lea

Mult Scler Relat Disord· August 2025

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Gene-Based Burden Testing of Rare Variants in Hemiplegic Migraine: A Computational Approach to Uncover the Genetic Architecture of a Rare Brain Disorder.
Mohammed M Alfayyadh, Neven Maksemous, Heidi G Sutherland, Rodney A Lea, Lyn R Griffiths

Genes (Basel)· July 2025

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New composite phenotypes enhance chronic kidney disease classification and genetic associations.
Kim Ngan Tran, Heidi G Sutherland, Andrew J Mallett, Lyn R Griffiths, Rodney A Lea

PLoS Genet· May 2025

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PathVar: A Customisable NGS Variant Calling Algorithm Implicates Novel Candidate Genes and Pathways in Hemiplegic Migraine.
Mohammed M Alfayyadh, Neven Maksemous, Heidi G Sutherland, Rodney A Lea, Lyn R Griffiths

Clin Genet· February 2025

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Longitudinal epidemiology of multiple sclerosis over 60 years in Newcastle, Australia: 1961 to 2021.
Steve Simpson-Yap, Vicki E Maltby, Stacey Hall, Sophia Ward, Rodney Lea

Mult Scler Relat Disord· October 2024

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Improvement of the thalamocortical white matter network in people with stable treated relapsing-remitting multiple sclerosis over time.
Abdulaziz Alshehri, Nikitas Koussis, Oun Al-Iedani, Ibrahim Khormi, Rodney Lea

NMR Biomed· June 2024

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The immune cell transcriptome is modulated by vitamin D supplementation in people with a first demyelinating event participating in a randomized placebo-controlled trial.
Wei Zhen Yeh, Melissa Gresle, Rodney Lea, Bruce Taylor, Robyn M Lucas

Clin Immunol· May 2024

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HLA-DRB1*15:01 and the Gene Interact to Selectively Influence the Profile of MERTK-Expressing Monocytes in Both Health and MS.
Michele D Binder, Eze C Nwoke, Ellen Morwitch, Chris Dwyer, Vivien Li, Rodney A Lea

Neurol Neuroimmunol Neuroinflamm· March 2024

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Novel genetic markers for chronic kidney disease in a geographically isolated population of Indigenous Australians: Individual and multiple phenotype genome-wide association study.
Vignesh Arunachalam, Rodney Lea, Wendy Hoy, Simon Lee, Susan Mott

Genome Med· February 2024

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Diffusion tensor imaging changes of the cortico-thalamic-striatal tracts correlate with fatigue and disability in people with relapsing-remitting MS.
Abdulaziz Alshehri, Nikitas Koussis, Oun Al-Iedani, Jameen Arm, Ibrahim Khormi, Stasson Lea, Rodney Lea

Eur J Radiol· January 2024

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A longitudinal analysis of brain volume changes in myelin oligodendrocyte glycoprotein antibody-associated disease.
Mohammad Amin, Oun Al-Iedani, Rodney A Lea, Fabienne Brilot, Vicki E Maltby

J Neuroimaging· January 2024

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Multi-modal neuroimaging signatures predict cognitive decline in multiple sclerosis: A 5-year longitudinal study.
Oun Al-Iedani, Stasson Lea, A Alshehri, Vicki E Maltby, Bente Saugbjerg, Rodney Lea

Mult Scler Relat Disord· January 2024

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Transcriptomics identifies blunted immunomodulatory effects of vitamin D in people with multiple sclerosis.
Wei Z Yeh, Rodney Lea, Jim Stankovich, Sandeep Sampangi, Louise Laverick

Sci Rep· January 2024

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Dairy and gluten in disease activity in multiple sclerosis.
Isabel A Temperley, Alexandra N Seldon, Madeline Aw Reckord, Claudia A Yarad, Farihah T Islam, Rodney A Lea

Mult Scler J Exp Transl Clin· December 2023

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CEST 2022 - Differences in APT-weighted signal in T1 weighted isointense lesions, black holes and normal-appearing white matter in people with relapsing-remitting multiple sclerosis.
Ibrahim Khormi, Oun Al-Iedani, Stefano Casagranda, Christos Papageorgakis, Abdulaziz Alshehri, Rodney Lea

Magn Reson Imaging· October 2023

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Conceiving complexity: Biological mechanisms underpinning the lasting effect of pregnancy on multiple sclerosis outcomes.
Maria Pia Campagna, Jeannette Lechner-Scott, Vicki E Maltby, Rodney A Lea, Helmut Butzkueven

Autoimmun Rev· September 2023

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Exonic mutations in cell-cell adhesion may contribute to CADASIL-related CSVD pathology.
Paul J Dunn, Rodney A Lea, Neven Maksemous, Robert A Smith, Heidi G Sutherland

Hum Genet· September 2023

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Exploring the Functional Basis of Epigenetic Aging in Relation to Body Fat Phenotypes in the Norfolk Island Cohort.
Thao Van Cao, Heidi G Sutherland, Miles C Benton, Larisa M Haupt, Rodney A Lea

Curr Issues Mol Biol· September 2023

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Evaluation of Cell-Specific Epigenetic Age Acceleration in People With Multiple Sclerosis.
Vicki Maltby, Alexandre Xavier, Ewoud Ewing, Maria-Pia Campagna, Sandeep Sampangi, Rodney Lea

Neurology· August 2023

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DNA Methylation Signatures of Multiple Sclerosis Occur Independently of Known Genetic Risk and Are Primarily Attributed to B Cells and Monocytes.
Alexandre Xavier, Vicki E Maltby, Ewoud Ewing, Maria Pia Campagna, Sean M Burnard, Rodney A Lea

Int J Mol Sci· August 2023

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Genetic Characterization of Blood Group Antigens for Polynesian Heritage Norfolk Island Residents.
Stacie O'Brien, Rodney A Lea, Sudhir Jadhao, Simon Lee, Shrey Sukhadia

Genes (Basel)· August 2023

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Interferon beta treatment is a potent and targeted epigenetic modifier in multiple sclerosis.
Alexandre Xavier, Maria Pia Campagna, Vicki E Maltby, Trevor Kilpatrick, Bruce V Taylor, Rodney A Lea

Front Immunol· June 2023

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