Publications by authors named "Rodrigo Somoza"

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CRISPRa genome-wide screen identifies novel gene targets for osteogenic cell engineering.
Jacob D Weston, Hunter Levis, Brandon Lawrence, Rodrigo Somoza, Robby D Bowles

J Tissue Eng· November 2025

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Amino Acid Uptake Limitations during Human Mesenchymal Stem Cell-Based Chondrogenesis.
Yi Zhong, Bo Zhang, Rodrigo Somoza, Arnold I Caplan, Jean F Welter

Tissue Eng Part A· January 2025

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Synergistic effects of biological stimuli and flexion induce microcavities promote hypertrophy and inhibit chondrogenesis during in vitro culture of human mesenchymal stem cell aggregates.
Bo Zhang, Jim Berilla, Sungwoo Cho, Rodrigo A Somoza, Jean F Welter

Biotechnol J· September 2024

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MSCs mediate long-term efficacy in a Crohn's disease model by sustained anti-inflammatory macrophage programming via efferocytosis.
Maneesh Dave, Atul Dev, Rodrigo A Somoza, Nan Zhao, Satish Viswanath

NPJ Regen Med· January 2024

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Mesenchymal stem cells ameliorate inflammation in an experimental model of Crohn's disease via the mesentery.
Maneesh Dave, Atul Dev, Rodrigo A Somoza, Nan Zhao, Satish Viswanath

bioRxiv· May 2023

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Multiplexed microfluidic chip for cell co-culture.
Craig Watson, Chao Liu, Ali Ansari, Helen C Miranda, Rodrigo A Somoza

Analyst· November 2022

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MicroRNA Regulation of Bone Marrow Mesenchymal Stem Cell Chondrogenesis: Toward Articular Cartilage.
Daniel J Vail, Rodrigo A Somoza, Arnold I Caplan

Tissue Eng Part A· March 2022

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The Releasate of Avascular Cartilage Demonstrates Inherent Pro-Angiogenic Properties and .
Yannick Nossin, Eric Farrell, Wendy J L M Koevoet, Frank Datema, Rodrigo A Somoza

Cartilage· December 2021

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Donor-defined mesenchymal stem cell antimicrobial potency against nontuberculous mycobacterium.
Tracey L Bonfield, Morgan T Sutton, David R Fletcher, Michael A Folz, Vaishnavi Ragavapuram, Rodrigo A Somoza

Stem Cells Transl Med· August 2021

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Isolation of Chondrocytes from Human Cartilage and Cultures in Monolayer and 3D.
Rodrigo A Somoza, Jean F Welter

Methods Mol Biol· March 2021

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The Habitat Assay, a Platform to Study Properties of Human Mesenchymal Stem Cells.
Donald P Lennon, Rodrigo A Somoza, Mark A Schluchter, Arnold I Caplan

Tissue Eng Part A· December 2020

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An Integrated Multi-Function Heterogeneous Biochemical Circuit for High-Resolution Electrochemistry-Based Genetic Analysis.
Yifan Dai, Wei Xu, Rodrigo A Somoza, Jean F Welter, Arnold I Caplan

Angew Chem Int Ed Engl· November 2020

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Enhanced Chondrogenic Capacity of Mesenchymal Stem Cells After TNFα Pre-treatment.
Chantal Voskamp, Wendy J L M Koevoet, Rodrigo A Somoza, Arnold I Caplan, Véronique Lefebvre

Front Bioeng Biotechnol· June 2020

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Angiogenic Potential of Tissue Engineered Cartilage From Human Mesenchymal Stem Cells Is Modulated by Indian Hedgehog and Serpin E1.
Yannick Nossin, Eric Farrell, Wendy J L M Koevoet, Rodrigo A Somoza, Arnold I Caplan

Front Bioeng Biotechnol· April 2020

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Transcriptome dynamics of long noncoding RNAs and transcription factors demarcate human neonatal, adult, and human mesenchymal stem cell-derived engineered cartilage.
Daniel J Vail, Rodrigo A Somoza, Arnold I Caplan, Ahmad M Khalil

J Tissue Eng Regen Med· January 2020

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Exploring the Trans-Cleavage Activity of CRISPR-Cas12a (cpf1) for the Development of a Universal Electrochemical Biosensor.
Yifan Dai, Rodrigo A Somoza, Liu Wang, Jean F Welter, Yan Li

Angew Chem Int Ed Engl· November 2019

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Analysis of -5p and -3p Strands of miR-145 and miR-140 During Mesenchymal Stem Cell Chondrogenic Differentiation.
Jonathan D Kenyon, Olga Sergeeva, Rodrigo A Somoza, Ming Li, Arnold I Caplan

Tissue Eng Part A· January 2019

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Human and Rat Bone Marrow-Derived Mesenchymal Stem Cells Differ in Their Response to Fibroblast Growth Factor and Platelet-Derived Growth Factor.
Donald Lennon, Luis A Solchaga, Rodrigo A Somoza, Mark D Schluchter, Seunghee Margevicius

Tissue Eng Part A· December 2018

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Human mesenchymal stem cells induced to differentiate as chondrocytes follow a biphasic pattern of extracellular matrix production.
J Michael Sorrell, Rodrigo A Somoza, Arnold I Caplan

J Orthop Res· June 2018

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Nondestructive/Noninvasive Imaging Evaluation of Cellular Differentiation Progression During In Vitro Mesenchymal Stem Cell-Derived Chondrogenesis.
Diego Correa, Rodrigo A Somoza, Arnold I Caplan

Tissue Eng Part A· April 2018

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Transcriptome-Wide Analyses of Human Neonatal Articular Cartilage and Human Mesenchymal Stem Cell-Derived Cartilage Provide a New Molecular Target for Evaluating Engineered Cartilage.
Rodrigo A Somoza, Diego Correa, Ivan Labat, Hal Sternberg, Megan E Forrest

Tissue Eng Part A· February 2018

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Ultrasound-guided Intracardiac Injection of Human Mesenchymal Stem Cells to Increase Homing to the Intestine for Use in Murine Models of Experimental Inflammatory Bowel Diseases.
Maneesh Dave, Paola Menghini, Keiki Sugi, Rodrigo A Somoza, Zhenghong Lee

J Vis Exp· September 2017

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TGFβ3 secretion by three-dimensional cultures of human dental apical papilla mesenchymal stem cells.
Rodrigo A Somoza, Cristian A Acevedo, Fernando Albornoz, Patricia Luz-Crawford, Flavio Carrión

J Tissue Eng Regen Med· April 2017

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Mesenchymal stem cells regulate melanoma cancer cells extravasation to bone and liver at their perivascular niche.
Diego Correa, Rodrigo A Somoza, Paul Lin, William P Schiemann, Arnold I Caplan

Int J Cancer· January 2016

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Chondrogenic differentiation of mesenchymal stem cells: challenges and unfulfilled expectations.
Rodrigo A Somoza, Jean F Welter, Diego Correa, Arnold I Caplan

Tissue Eng Part B Rev· December 2014

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