Publications by authors named "Roger Brookes"

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Formulation development of a stable influenza recombinant neuraminidase vaccine candidate.
Bing Li, Irina V Ustyugova, Lisa Szymkowicz, Shaolong Zhu, Marin Ming, Roger H Brookes

Hum Vaccin Immunother· December 2024

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Aluminum hydroxide adjuvant diverts the uptake and trafficking of genetically detoxified pertussis toxin to lysosomes in macrophages.
Javier Jaldin-Fincati, Serene Moussaoui, Maria Cecilia Gimenez, Cheuk Y Ho, Charlene E Lancaster, Roger Brookes

Mol Microbiol· May 2022

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Immunocartography: Charting vaccine-driven immunity by applying single cell proteomics to an in vitro human model.
Jessica S Duprez, Michael Cohen, Stephen Li, Derek Wilson, Roger H Brookes

J Immunol Methods· August 2021

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Genetically detoxified pertussis toxin displays near identical structure to its wild-type and exhibits robust immunogenicity.
Salvador F Ausar, Shaolong Zhu, Jessica Duprez, Michael Cohen, Thomas Bertrand, Roger H Brookes

Commun Biol· August 2020

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Screening Vaccine Formulations in Fresh Human Whole Blood.
Jalil Hakimi, Sepideh Aboutorabian, Frederick To, Salvador F Ausar, Nausheen Rahman, Roger H Brookes

Methods Mol Biol· January 2018

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An adjuvant-modulated vaccine response in human whole blood.
Jalil Hakimi, Ali Azizi, Salvador F Ausar, Stephen M Todryk, Nausheen Rahman, Roger H Brookes

Hum Vaccin Immunother· September 2017

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Infection in Close Childhood Contacts of Adults with Pulmonary Tuberculosis is Increased by Secondhand Exposure to Tobacco.
Ifedayo M O Adetifa, Lindsay Kendall, Simon Donkor, Moses D Lugos, Abdulrahman S Hammond, Roger H Brookes

Am J Trop Med Hyg· August 2017

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A bivalent pneumococcal histidine triad protein D-choline-binding protein A vaccine elicits functional antibodies that passively protect mice from Streptococcus pneumoniae challenge.
Martina M Ochs, Kimberley Williams, Anthony Sheung, Philippe Lheritier, Lucian Visan, Roger H Brookes

Hum Vaccin Immunother· November 2016

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Screening vaccine formulations for biological activity using fresh human whole blood.
Roger H Brookes, Jalil Hakimi, Yukyung Ha, Sepideh Aboutorabian, Salvador F Ausar

Hum Vaccin Immunother· April 2016

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Passive protection of mice against Streptococcus pneumoniae challenge by naturally occurring and vaccine-induced human anti-PhtD antibodies.
Roger H Brookes, Marin Ming, Kimberley Williams, Robert Hopfer, Sanjay Gurunathan

Hum Vaccin Immunother· April 2016

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A high ratio of IC31(®) adjuvant to antigen is necessary for H4 TB vaccine immunomodulation.
Sepideh Aboutorabian, Jalil Hakimi, Florence Boudet, Sandrine Montano, Annie Dookie, Roger H Brookes

Hum Vaccin Immunother· March 2016

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Elevated inflammatory markers combined with positive pneumococcal urinary antigen are a good predictor of pneumococcal community-acquired pneumonia in children.
Annick Galetto-Lacour, Gabriel Alcoba, Klara M Posfay-Barbe, Manon Cevey-Macherel, Mario Gehri, Roger H Brookes

Pediatr Infect Dis J· November 2013

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Interferon-γ ELISPOT as a biomarker of treatment efficacy in latent tuberculosis infection: a clinical trial.
Ifedayo M Adetifa, Martin O C Ota, David J Jeffries, Moses D Lugos, Abdulrahman S Hammond, Roger H Brookes

Am J Respir Crit Care Med· February 2013

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Safety and immunogenicity of a pneumococcal histidine triad protein D vaccine candidate in adults.
Michael Seiberling, Monica Bologa, Roger Brookes, Martina Ochs, Kerry Go

Vaccine· December 2012

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Characterization of Melan-A reactive memory CD8+ T cells in a healthy donor.
Verena Voelter, Nathalie Rufer, Severine Reynard, Gilbert Greub, Roger Brookes

Int Immunol· August 2008

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Safety and immunogenicity of the candidate tuberculosis vaccine MVA85A in West Africa.
Roger H Brookes, Philip C Hill, Patrick K Owiafe, Hannah B Ibanga, David J Jeffries

PLoS One· August 2008

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Incidence of tuberculosis and the predictive value of ELISPOT and Mantoux tests in Gambian case contacts.
Philip C Hill, Dolly J Jackson-Sillah, Annette Fox, Roger H Brookes, Bouke C de Jong

PLoS One· January 2008

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Mycobacterial T cell responses in HIV-infected patients with advanced immunosuppression.
Abdulrahman S Hammond, Samuel J McConkey, Philip C Hill, Sarah Crozier, Michèl R Klein, Roger H Brookes

J Infect Dis· January 2008

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The effect of tuberculin skin test and BCG vaccination on the expansion of PPD-specific IFN-gamma producing cells ex vivo.
Martin O C Ota, Roger H Brookes, Philip C Hill, Patrick K Owiafe, Hannah B Ibanga

Vaccine· December 2007

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ESAT-6 and CFP-10 can be combined to reduce the cost of testing for Mycobacterium tuberculosis infection, but CFP-10 responses associate with active disease.
Annette Fox, David J Jeffries, Philip C Hill, Abdulrahman S Hammond, Moses D Lugos, Roger H Brookes

Trans R Soc Trop Med Hyg· July 2007

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Screening for tuberculosis among 2381 household contacts of sputum-smear-positive cases in The Gambia.
Dolly Jackson-Sillah, Philip C Hill, Annette Fox, Roger H Brookes, Simon A Donkor

Trans R Soc Trop Med Hyg· June 2007

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Extended culture enhances sensitivity of a gamma interferon assay for latent Mycobacterium tuberculosis infection.
Ana Cehovin, Jacqueline M Cliff, Philip C Hill, Roger H Brookes, Hazel M Dockrell

Clin Vaccine Immunol· June 2007

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Longitudinal assessment of an ELISPOT test for Mycobacterium tuberculosis infection.
Philip C Hill, Roger H Brookes, Annette Fox, Dolly Jackson-Sillah, David J Jeffries

PLoS Med· June 2007

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Using ELISPOT to expose false positive skin test conversion in tuberculosis contacts.
Philip C Hill, David J Jeffries, Roger H Brookes, Annette Fox, Dolly Jackson-Sillah

PLoS One· January 2007

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Surprisingly high specificity of the PPD skin test for M. tuberculosis infection from recent exposure in The Gambia.
Philip C Hill, Roger H Brookes, Annette Fox, Dolly Jackson-Sillah, Moses D Lugos

PLoS One· December 2006

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