Publications by authors named "Roger D Cox"

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IRX3 controls a SUMOylation-dependent differentiation switch in adipocyte precursor cells.
Jan-Inge Bjune, Samantha Laber, Laurence Lawrence-Archer, Patrizia M C Nothnagel, Shuntaro Yamada, Roger D Cox

Nat Commun· August 2025

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Loss of reduces adipogenesis and improves insulin sensitivity in mouse and human adipocytes.
Grace Z Yu, Nicole A J Krentz, Liz Bentley, Meng Zhao, Keanu Paphiti, Roger D Cox

bioRxiv· July 2024

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The genetics of adipose tissue metabolism.
Rebecca Dumbell, Roger D Cox

R Soc Open Sci· February 2024

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Cysteine-lowering treatment with mesna against obesity: Proof of concept and results from a human phase I, dose-finding study.
Kathrine J Vinknes, Thomas Olsen, Hasse Khiabani Zaré, Nasser E Bastani, Emma Stolt, Roger D Cox

Diabetes Obes Metab· November 2023

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Cleft palate and minor metabolic disturbances in a mouse global Arl15 gene knockout.
Ying Bai, Liz Bentley, Chao Ma, Navaratnam Naveenan, James Cleak, Roger D Cox

FASEB J· November 2023

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A Mouse Model with a Frameshift Mutation in the Nuclear Factor I/X () Gene Has Phenotypic Features of Marshall-Smith Syndrome.
Kreepa G Kooblall, Mark Stevenson, Michelle Stewart, Lachlan Harris, Oressia Zalucki, Roger D Cox

JBMR Plus· June 2023

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A mutant mouse shows a sex and diet specific change in fat distribution, reduced food intake and depot-specific upregulation of WAT browning.
Milan Mušo, Liz Bentley, Lucie Vizor, Marianne Yon, Keith Burling, Roger D Cox

Front Physiol· August 2022

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AKR1D1 knockout mice develop a sex-dependent metabolic phenotype.
Laura L Gathercole, Nikolaos Nikolaou, Shelley E Harris, Anastasia Arvaniti, Toryn M Poolman, Roger D Cox

J Endocrinol· April 2022

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Palmitoylated small GTPase ARL15 is translocated within Golgi network during adipogenesis.
Yixing Wu, Ying Bai, David G McEwan, Liz Bentley, Dimitra Aravani, Roger D Cox

Biol Open· December 2021

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Linking the obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo.
Samantha Laber, Sara Forcisi, Liz Bentley, Julia Petzold, Franco Moritz, Roger D Cox

Sci Adv· July 2021

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The Gene Variant Hastens Diabetes Progression by Impairing Glucose-Induced Insulin Secretion.
Gregor Sachse, Elizabeth Haythorne, Thomas Hill, Peter Proks, Russell Joynson, Roger D Cox

Diabetes· May 2021

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A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density.
Nasa Sinnott-Armstrong, Isabel S Sousa, Samantha Laber, Elizabeth Rendina-Ruedy, Simon E Nitter Dankel, Roger D Cox

Cell Metab· March 2021

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Maternal and offspring high-fat diet leads to platelet hyperactivation in male mice offspring.
Renato S Gaspar, Amanda J Unsworth, Alaa Al-Dibouni, Alexander P Bye, Tanya Sage, Roger D Cox

Sci Rep· January 2021

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A lead candidate functional single nucleotide polymorphism within the WARS2 gene associated with waist-hip-ratio does not alter RNA stability.
Milan Mušo, Rebecca Dumbell, Sara Pulit, Nasa Sinnott-Armstrong, Samantha Laber, Roger D Cox

Biochim Biophys Acta Gene Regul Mech· November 2020

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Calcilytic NPSP795 Increases Plasma Calcium and PTH in an Autosomal Dominant Hypocalcemia Type 1 Mouse Model.
Fadil M Hannan, Caroline M Gorvin, Valerie N Babinsky, Mie K Olesen, Michelle Stewart, Roger D Cox

JBMR Plus· October 2020

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The American lifestyle-induced obesity syndrome diet in male and female rodents recapitulates the clinical and transcriptomic features of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.
Shelley E Harris, Toryn M Poolman, Anastasia Arvaniti, Roger D Cox, Laura L Gathercole

Am J Physiol Gastrointest Liver Physiol· September 2020

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null C57BL/6N mice develop cardiomyopathy, whereas null C57BL/6J mice do not.
Jack L Williams, Anju Paudyal, Sherine Awad, James Nicholson, Dominika Grzesik, Roger D Cox

Life Sci Alliance· April 2020

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A novel mutation in the mouse Pcsk1 gene showing obesity and diabetes.
Nor I A Muhsin, Liz Bentley, Ying Bai, Michelle Goldsworthy, Roger D Cox

Mamm Genome· February 2020

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The development of a high throughput drug-responsive model of white adipose tissue comprising adipogenic 3T3-L1 cells in a 3D matrix.
Alexander D Graham, Rajesh Pandey, Viktoriya S Tsancheva, Alessia Candeo, Stanley W Botchway, Roger D Cox

Biofabrication· December 2019

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Monitoring type 2 diabetes from volatile faecal metabolome in Cushing's syndrome and single Afmid mouse models via a longitudinal study.
Célia Lourenço, Darren Kelly, Jack Cantillon, Michael Cauchi, Marianne A Yon, Roger D Cox

Sci Rep· December 2019

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Abcc5 Knockout Mice Have Lower Fat Mass and Increased Levels of Circulating GLP-1.
Malgorzata Cyranka, Anna Veprik, Eleanor J McKay, Nienke van Loon, Amber Thijsse, Roger D Cox

Obesity (Silver Spring)· August 2019

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Mice with a Brd4 Mutation Represent a New Model of Nephrocalcinosis.
Caroline M Gorvin, Nellie Y Loh, Michael J Stechman, Sara Falcone, Fadil M Hannan, Roger D Cox

J Bone Miner Res· July 2019

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An N-Ethyl-N-Nitrosourea (ENU)-Induced Tyr265Stop Mutation of the DNA Polymerase Accessory Subunit Gamma 2 (Polg2) Is Associated With Renal Calcification in Mice.
Caroline M Gorvin, Bushra N Ahmad, Michael J Stechman, Nellie Y Loh, Tertius A Hough, Roger D Cox

J Bone Miner Res· March 2019

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A Wars2 Mutant Mouse Model Displays OXPHOS Deficiencies and Activation of Tissue-Specific Stress Response Pathways.
Thomas Agnew, Michelle Goldsworthy, Carlos Aguilar, Anna Morgan, Michelle Simon, Roger D Cox

Cell Rep· December 2018

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An -Ethyl--Nitrosourea (ENU) Mutagenized Mouse Model for Autosomal Dominant Nonsyndromic Kyphoscoliosis Due to Vertebral Fusion.
Christopher T Esapa, Sian E Piret, M Andrew Nesbit, Gethin P Thomas, Leslie A Coulton, Roger D Cox

JBMR Plus· May 2018

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